7PMY
HsPepT2 bound to Ala-Phe in the inward facing partially occluded conformation
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006857 | biological_process | oligopeptide transport |
| A | 0015333 | molecular_function | peptide:proton symporter activity |
| A | 0015835 | biological_process | peptidoglycan transport |
| A | 0016020 | cellular_component | membrane |
| A | 0016324 | cellular_component | apical plasma membrane |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0030670 | cellular_component | phagocytic vesicle membrane |
| A | 0035673 | molecular_function | oligopeptide transmembrane transporter activity |
| A | 0042908 | biological_process | xenobiotic transport |
| A | 0042937 | molecular_function | tripeptide transmembrane transporter activity |
| A | 0042938 | biological_process | dipeptide transport |
| A | 0055085 | biological_process | transmembrane transport |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0070293 | biological_process | renal absorption |
| A | 0070424 | biological_process | regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway |
| A | 0071916 | molecular_function | dipeptide transmembrane transporter activity |
| A | 0140206 | biological_process | dipeptide import across plasma membrane |
| A | 0140207 | biological_process | tripeptide import across plasma membrane |
| A | 0140367 | biological_process | antibacterial innate immune response |
| A | 0150104 | biological_process | transport across blood-brain barrier |
| A | 1902600 | biological_process | proton transmembrane transport |
| A | 1990961 | biological_process | xenobiotic detoxification by transmembrane export across the plasma membrane |
Functional Information from PROSITE/UniProt
| site_id | PS01022 |
| Number of Residues | 25 |
| Details | PTR2_1 PTR2 family proton/oligopeptide symporters signature 1. GAAIADsWLGkfkTIiylSlVyvlG |
| Chain | Residue | Details |
| A | GLY100-GLY124 |
| site_id | PS01023 |
| Number of Residues | 13 |
| Details | PTR2_2 PTR2 family proton/oligopeptide symporters signature 2. FsvFYLsINAGSL |
| Chain | Residue | Details |
| A | PHE184-LEU196 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 240 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 264 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 111 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 209 |
| Details | Region: {"description":"Extracellular domain (ECD)","evidences":[{"source":"UniProtKB","id":"Q63424","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 5 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00498","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
