7PMW
HsPepT1 bound to Ala-Phe in the outward facing occluded conformation
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005427 | molecular_function | proton-dependent oligopeptide secondary active transmembrane transporter activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0005903 | cellular_component | brush border |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0006857 | biological_process | oligopeptide transport |
| A | 0015031 | biological_process | protein transport |
| A | 0015293 | molecular_function | symporter activity |
| A | 0015333 | molecular_function | peptide:proton symporter activity |
| A | 0015833 | biological_process | peptide transport |
| A | 0016020 | cellular_component | membrane |
| A | 0016324 | cellular_component | apical plasma membrane |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0035673 | molecular_function | oligopeptide transmembrane transporter activity |
| A | 0042937 | molecular_function | tripeptide transmembrane transporter activity |
| A | 0055085 | biological_process | transmembrane transport |
| A | 0071916 | molecular_function | dipeptide transmembrane transporter activity |
| A | 0140206 | biological_process | dipeptide import across plasma membrane |
| A | 0140207 | biological_process | tripeptide import across plasma membrane |
| A | 1902600 | biological_process | proton transmembrane transport |
Functional Information from PROSITE/UniProt
| site_id | PS01022 |
| Number of Residues | 25 |
| Details | PTR2_1 PTR2 family proton/oligopeptide symporters signature 1. GALIADsWLGkfkTIvslSiVytiG |
| Chain | Residue | Details |
| A | GLY70-GLY94 |
| site_id | PS01023 |
| Number of Residues | 13 |
| Details | PTR2_2 PTR2 family proton/oligopeptide symporters signature 2. FsiFYLaINAGSL |
| Chain | Residue | Details |
| A | PHE163-LEU175 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 200 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 109 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 234 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 201 |
| Details | Region: {"description":"Extracellular domain (ECD)","evidences":[{"source":"UniProtKB","id":"Q9JIP7","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 7 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
