7PK5

Phosphodiesterase PdeL (EAL domain of crystals comprising full-length protein)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0003677	molecular_function	DNA binding
A	0006355	biological_process	regulation of DNA-templated transcription
A	0016787	molecular_function	hydrolase activity
A	0042803	molecular_function	protein homodimerization activity
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0046872	molecular_function	metal ion binding
A	0071111	molecular_function	cyclic-guanylate-specific phosphodiesterase activity
B	0000976	molecular_function	transcription cis-regulatory region binding
B	0003677	molecular_function	DNA binding
B	0006355	biological_process	regulation of DNA-templated transcription
B	0016787	molecular_function	hydrolase activity
B	0042803	molecular_function	protein homodimerization activity
B	0045893	biological_process	positive regulation of DNA-templated transcription
B	0046872	molecular_function	metal ion binding
B	0071111	molecular_function	cyclic-guanylate-specific phosphodiesterase activity
C	0000976	molecular_function	transcription cis-regulatory region binding
C	0003677	molecular_function	DNA binding
C	0006355	biological_process	regulation of DNA-templated transcription
C	0016787	molecular_function	hydrolase activity
C	0042803	molecular_function	protein homodimerization activity
C	0045893	biological_process	positive regulation of DNA-templated transcription
C	0046872	molecular_function	metal ion binding
C	0071111	molecular_function	cyclic-guanylate-specific phosphodiesterase activity
D	0000976	molecular_function	transcription cis-regulatory region binding
D	0003677	molecular_function	DNA binding
D	0006355	biological_process	regulation of DNA-templated transcription
D	0016787	molecular_function	hydrolase activity
D	0042803	molecular_function	protein homodimerization activity
D	0045893	biological_process	positive regulation of DNA-templated transcription
D	0046872	molecular_function	metal ion binding
D	0071111	molecular_function	cyclic-guanylate-specific phosphodiesterase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	76
Details	DNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00411

Chain	Residue	Details
A	VAL42-LYS61
D	VAL42-LYS61
B	VAL42-LYS61
C	VAL42-LYS61

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site_id	SWS_FT_FI2
Number of Residues	28
Details	BINDING: BINDING => ECO:0000269|PubMed:24451384, ECO:0007744|PDB:4LJ3

Chain	Residue	Details
A	GLN127
D	ASN200
D	ASP262
D	LYS286
D	GLU319
D	TYR341
B	GLN127
B	VAL144
B	ASN200
B	ASP262
B	LYS286
A	VAL144
B	GLU319
B	TYR341
C	GLN127
C	VAL144
C	ASN200
C	ASP262
C	LYS286
C	GLU319
C	TYR341
A	ASN200
A	ASP262
A	LYS286
A	GLU319
A	TYR341
D	GLN127
D	VAL144

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site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:24451384, ECO:0007744|PDB:4LYK

Chain	Residue	Details
A	GLU141
A	GLU232
D	GLU141
D	GLU232
B	GLU141
B	GLU232
C	GLU141
C	GLU232

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