Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7PEQ

Model of the outer rings of the human nuclear pore complex

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AC	0000776	cellular_component	kinetochore
AC	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
AC	0005515	molecular_function	protein binding
AC	0005635	cellular_component	nuclear envelope
AC	0005643	cellular_component	nuclear pore
AC	0005829	cellular_component	cytosol
AC	0006406	biological_process	mRNA export from nucleus
AC	0006606	biological_process	protein import into nucleus
AC	0006913	biological_process	nucleocytoplasmic transport
AC	0006999	biological_process	nuclear pore organization
AC	0015031	biological_process	protein transport
AC	0016020	cellular_component	membrane
AC	0016973	biological_process	poly(A)+ mRNA export from nucleus
AC	0017056	molecular_function	structural constituent of nuclear pore
AC	0031080	cellular_component	nuclear pore outer ring
AC	0031965	cellular_component	nuclear membrane
AC	0048513	biological_process	animal organ development
AC	0048731	biological_process	system development
AC	0051028	biological_process	mRNA transport
AC	0072006	biological_process	nephron development
AD	0000776	cellular_component	kinetochore
AD	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
AD	0005515	molecular_function	protein binding
AD	0005635	cellular_component	nuclear envelope
AD	0005643	cellular_component	nuclear pore
AD	0005829	cellular_component	cytosol
AD	0006406	biological_process	mRNA export from nucleus
AD	0006606	biological_process	protein import into nucleus
AD	0006913	biological_process	nucleocytoplasmic transport
AD	0008585	biological_process	female gonad development
AD	0015031	biological_process	protein transport
AD	0016020	cellular_component	membrane
AD	0017056	molecular_function	structural constituent of nuclear pore
AD	0031080	cellular_component	nuclear pore outer ring
AD	0031965	cellular_component	nuclear membrane
AD	0034399	cellular_component	nuclear periphery
AD	0051028	biological_process	mRNA transport
AD	0051292	biological_process	nuclear pore complex assembly
AD	0072006	biological_process	nephron development
AF	0000776	cellular_component	kinetochore
AF	0005198	molecular_function	structural molecule activity
AF	0005515	molecular_function	protein binding
AF	0005635	cellular_component	nuclear envelope
AF	0005643	cellular_component	nuclear pore
AF	0005654	cellular_component	nucleoplasm
AF	0005765	cellular_component	lysosomal membrane
AF	0005783	cellular_component	endoplasmic reticulum
AF	0005789	cellular_component	endoplasmic reticulum membrane
AF	0005829	cellular_component	cytosol
AF	0006606	biological_process	protein import into nucleus
AF	0006886	biological_process	intracellular protein transport
AF	0006913	biological_process	nucleocytoplasmic transport
AF	0012507	cellular_component	ER to Golgi transport vesicle membrane
AF	0015031	biological_process	protein transport
AF	0016192	biological_process	vesicle-mediated transport
AF	0030127	cellular_component	COPII vesicle coat
AF	0031080	cellular_component	nuclear pore outer ring
AF	0031410	cellular_component	cytoplasmic vesicle
AF	0031669	biological_process	cellular response to nutrient levels
AF	0032008	biological_process	positive regulation of TOR signaling
AF	0032527	biological_process	protein exit from endoplasmic reticulum
AF	0042802	molecular_function	identical protein binding
AF	0051028	biological_process	mRNA transport
AF	0061700	cellular_component	GATOR2 complex
AF	0070062	cellular_component	extracellular exosome
AF	0070863	biological_process	positive regulation of protein exit from endoplasmic reticulum
AF	0090110	biological_process	COPII-coated vesicle cargo loading
AF	0090114	biological_process	COPII-coated vesicle budding
AF	1902953	biological_process	positive regulation of ER to Golgi vesicle-mediated transport
AF	1904262	biological_process	negative regulation of TORC1 signaling
AF	1904263	biological_process	positive regulation of TORC1 signaling
AG	0000776	cellular_component	kinetochore
AG	0005198	molecular_function	structural molecule activity
AG	0005515	molecular_function	protein binding
AG	0005635	cellular_component	nuclear envelope
AG	0005643	cellular_component	nuclear pore
AG	0005765	cellular_component	lysosomal membrane
AG	0005829	cellular_component	cytosol
AG	0006913	biological_process	nucleocytoplasmic transport
AG	0006999	biological_process	nuclear pore organization
AG	0007059	biological_process	chromosome segregation
AG	0007080	biological_process	mitotic metaphase chromosome alignment
AG	0015031	biological_process	protein transport
AG	0031080	cellular_component	nuclear pore outer ring
AG	0031503	biological_process	protein-containing complex localization
AG	0031669	biological_process	cellular response to nutrient levels
AG	0034198	biological_process	cellular response to amino acid starvation
AG	0035859	cellular_component	Seh1-associated complex
AG	0051028	biological_process	mRNA transport
AG	0051301	biological_process	cell division
AG	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
AG	0061700	cellular_component	GATOR2 complex
AG	1904262	biological_process	negative regulation of TORC1 signaling
AG	1904263	biological_process	positive regulation of TORC1 signaling
AH	0000776	cellular_component	kinetochore
AH	0005515	molecular_function	protein binding
AH	0005635	cellular_component	nuclear envelope
AH	0005643	cellular_component	nuclear pore
AH	0005654	cellular_component	nucleoplasm
AH	0005737	cellular_component	cytoplasm
AH	0005819	cellular_component	spindle
AH	0005829	cellular_component	cytosol
AH	0006406	biological_process	mRNA export from nucleus
AH	0006606	biological_process	protein import into nucleus
AH	0006913	biological_process	nucleocytoplasmic transport
AH	0015031	biological_process	protein transport
AH	0016020	cellular_component	membrane
AH	0017056	molecular_function	structural constituent of nuclear pore
AH	0031080	cellular_component	nuclear pore outer ring
AH	0031965	cellular_component	nuclear membrane
AH	0045893	biological_process	positive regulation of DNA-templated transcription
AH	0051028	biological_process	mRNA transport
AH	0072006	biological_process	nephron development
AI	0000776	cellular_component	kinetochore
AI	0005515	molecular_function	protein binding
AI	0005635	cellular_component	nuclear envelope
AI	0005643	cellular_component	nuclear pore
AI	0005654	cellular_component	nucleoplasm
AI	0005829	cellular_component	cytosol
AI	0006913	biological_process	nucleocytoplasmic transport
AI	0007059	biological_process	chromosome segregation
AI	0015031	biological_process	protein transport
AI	0031080	cellular_component	nuclear pore outer ring
AI	0051028	biological_process	mRNA transport
AI	0051301	biological_process	cell division
AJ	0000776	cellular_component	kinetochore
AJ	0005515	molecular_function	protein binding
AJ	0005635	cellular_component	nuclear envelope
AJ	0005643	cellular_component	nuclear pore
AJ	0005829	cellular_component	cytosol
AJ	0006406	biological_process	mRNA export from nucleus
AJ	0006913	biological_process	nucleocytoplasmic transport
AJ	0015031	biological_process	protein transport
AJ	0017056	molecular_function	structural constituent of nuclear pore
AJ	0031080	cellular_component	nuclear pore outer ring
AJ	0051028	biological_process	mRNA transport
AJ	0072006	biological_process	nephron development
AK	0000776	cellular_component	kinetochore
AK	0005515	molecular_function	protein binding
AK	0005634	cellular_component	nucleus
AK	0005635	cellular_component	nuclear envelope
AK	0005643	cellular_component	nuclear pore
AK	0005654	cellular_component	nucleoplasm
AK	0005829	cellular_component	cytosol
AK	0006913	biological_process	nucleocytoplasmic transport
AK	0007059	biological_process	chromosome segregation
AK	0015031	biological_process	protein transport
AK	0031080	cellular_component	nuclear pore outer ring
AK	0051028	biological_process	mRNA transport
AK	0051301	biological_process	cell division
BC	0000776	cellular_component	kinetochore
BC	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
BC	0005515	molecular_function	protein binding
BC	0005635	cellular_component	nuclear envelope
BC	0005643	cellular_component	nuclear pore
BC	0005829	cellular_component	cytosol
BC	0006406	biological_process	mRNA export from nucleus
BC	0006606	biological_process	protein import into nucleus
BC	0006913	biological_process	nucleocytoplasmic transport
BC	0006999	biological_process	nuclear pore organization
BC	0015031	biological_process	protein transport
BC	0016020	cellular_component	membrane
BC	0016973	biological_process	poly(A)+ mRNA export from nucleus
BC	0017056	molecular_function	structural constituent of nuclear pore
BC	0031080	cellular_component	nuclear pore outer ring
BC	0031965	cellular_component	nuclear membrane
BC	0048513	biological_process	animal organ development
BC	0048731	biological_process	system development
BC	0051028	biological_process	mRNA transport
BC	0072006	biological_process	nephron development
BD	0000776	cellular_component	kinetochore
BD	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
BD	0005515	molecular_function	protein binding
BD	0005635	cellular_component	nuclear envelope
BD	0005643	cellular_component	nuclear pore
BD	0005829	cellular_component	cytosol
BD	0006406	biological_process	mRNA export from nucleus
BD	0006606	biological_process	protein import into nucleus
BD	0006913	biological_process	nucleocytoplasmic transport
BD	0008585	biological_process	female gonad development
BD	0015031	biological_process	protein transport
BD	0016020	cellular_component	membrane
BD	0017056	molecular_function	structural constituent of nuclear pore
BD	0031080	cellular_component	nuclear pore outer ring
BD	0031965	cellular_component	nuclear membrane
BD	0034399	cellular_component	nuclear periphery
BD	0051028	biological_process	mRNA transport
BD	0051292	biological_process	nuclear pore complex assembly
BD	0072006	biological_process	nephron development
BF	0000776	cellular_component	kinetochore
BF	0005198	molecular_function	structural molecule activity
BF	0005515	molecular_function	protein binding
BF	0005635	cellular_component	nuclear envelope
BF	0005643	cellular_component	nuclear pore
BF	0005654	cellular_component	nucleoplasm
BF	0005765	cellular_component	lysosomal membrane
BF	0005783	cellular_component	endoplasmic reticulum
BF	0005789	cellular_component	endoplasmic reticulum membrane
BF	0005829	cellular_component	cytosol
BF	0006606	biological_process	protein import into nucleus
BF	0006886	biological_process	intracellular protein transport
BF	0006913	biological_process	nucleocytoplasmic transport
BF	0012507	cellular_component	ER to Golgi transport vesicle membrane
BF	0015031	biological_process	protein transport
BF	0016192	biological_process	vesicle-mediated transport
BF	0030127	cellular_component	COPII vesicle coat
BF	0031080	cellular_component	nuclear pore outer ring
BF	0031410	cellular_component	cytoplasmic vesicle
BF	0031669	biological_process	cellular response to nutrient levels
BF	0032008	biological_process	positive regulation of TOR signaling
BF	0032527	biological_process	protein exit from endoplasmic reticulum
BF	0042802	molecular_function	identical protein binding
BF	0051028	biological_process	mRNA transport
BF	0061700	cellular_component	GATOR2 complex
BF	0070062	cellular_component	extracellular exosome
BF	0070863	biological_process	positive regulation of protein exit from endoplasmic reticulum
BF	0090110	biological_process	COPII-coated vesicle cargo loading
BF	0090114	biological_process	COPII-coated vesicle budding
BF	1902953	biological_process	positive regulation of ER to Golgi vesicle-mediated transport
BF	1904262	biological_process	negative regulation of TORC1 signaling
BF	1904263	biological_process	positive regulation of TORC1 signaling
BG	0000776	cellular_component	kinetochore
BG	0005198	molecular_function	structural molecule activity
BG	0005515	molecular_function	protein binding
BG	0005635	cellular_component	nuclear envelope
BG	0005643	cellular_component	nuclear pore
BG	0005765	cellular_component	lysosomal membrane
BG	0005829	cellular_component	cytosol
BG	0006913	biological_process	nucleocytoplasmic transport
BG	0006999	biological_process	nuclear pore organization
BG	0007059	biological_process	chromosome segregation
BG	0007080	biological_process	mitotic metaphase chromosome alignment
BG	0015031	biological_process	protein transport
BG	0031080	cellular_component	nuclear pore outer ring
BG	0031503	biological_process	protein-containing complex localization
BG	0031669	biological_process	cellular response to nutrient levels
BG	0034198	biological_process	cellular response to amino acid starvation
BG	0035859	cellular_component	Seh1-associated complex
BG	0051028	biological_process	mRNA transport
BG	0051301	biological_process	cell division
BG	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
BG	0061700	cellular_component	GATOR2 complex
BG	1904262	biological_process	negative regulation of TORC1 signaling
BG	1904263	biological_process	positive regulation of TORC1 signaling
BH	0000776	cellular_component	kinetochore
BH	0005515	molecular_function	protein binding
BH	0005635	cellular_component	nuclear envelope
BH	0005643	cellular_component	nuclear pore
BH	0005654	cellular_component	nucleoplasm
BH	0005737	cellular_component	cytoplasm
BH	0005819	cellular_component	spindle
BH	0005829	cellular_component	cytosol
BH	0006406	biological_process	mRNA export from nucleus
BH	0006606	biological_process	protein import into nucleus
BH	0006913	biological_process	nucleocytoplasmic transport
BH	0015031	biological_process	protein transport
BH	0016020	cellular_component	membrane
BH	0017056	molecular_function	structural constituent of nuclear pore
BH	0031080	cellular_component	nuclear pore outer ring
BH	0031965	cellular_component	nuclear membrane
BH	0045893	biological_process	positive regulation of DNA-templated transcription
BH	0051028	biological_process	mRNA transport
BH	0072006	biological_process	nephron development
BI	0000776	cellular_component	kinetochore
BI	0005515	molecular_function	protein binding
BI	0005635	cellular_component	nuclear envelope
BI	0005643	cellular_component	nuclear pore
BI	0005654	cellular_component	nucleoplasm
BI	0005829	cellular_component	cytosol
BI	0006913	biological_process	nucleocytoplasmic transport
BI	0007059	biological_process	chromosome segregation
BI	0015031	biological_process	protein transport
BI	0031080	cellular_component	nuclear pore outer ring
BI	0051028	biological_process	mRNA transport
BI	0051301	biological_process	cell division
BJ	0000776	cellular_component	kinetochore
BJ	0005515	molecular_function	protein binding
BJ	0005635	cellular_component	nuclear envelope
BJ	0005643	cellular_component	nuclear pore
BJ	0005829	cellular_component	cytosol
BJ	0006406	biological_process	mRNA export from nucleus
BJ	0006913	biological_process	nucleocytoplasmic transport
BJ	0015031	biological_process	protein transport
BJ	0017056	molecular_function	structural constituent of nuclear pore
BJ	0031080	cellular_component	nuclear pore outer ring
BJ	0051028	biological_process	mRNA transport
BJ	0072006	biological_process	nephron development
BK	0000776	cellular_component	kinetochore
BK	0005515	molecular_function	protein binding
BK	0005634	cellular_component	nucleus
BK	0005635	cellular_component	nuclear envelope
BK	0005643	cellular_component	nuclear pore
BK	0005654	cellular_component	nucleoplasm
BK	0005829	cellular_component	cytosol
BK	0006913	biological_process	nucleocytoplasmic transport
BK	0007059	biological_process	chromosome segregation
BK	0015031	biological_process	protein transport
BK	0031080	cellular_component	nuclear pore outer ring
BK	0051028	biological_process	mRNA transport
BK	0051301	biological_process	cell division
CC	0000776	cellular_component	kinetochore
CC	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
CC	0005515	molecular_function	protein binding
CC	0005635	cellular_component	nuclear envelope
CC	0005643	cellular_component	nuclear pore
CC	0005829	cellular_component	cytosol
CC	0006406	biological_process	mRNA export from nucleus
CC	0006606	biological_process	protein import into nucleus
CC	0006913	biological_process	nucleocytoplasmic transport
CC	0006999	biological_process	nuclear pore organization
CC	0015031	biological_process	protein transport
CC	0016020	cellular_component	membrane
CC	0016973	biological_process	poly(A)+ mRNA export from nucleus
CC	0017056	molecular_function	structural constituent of nuclear pore
CC	0031080	cellular_component	nuclear pore outer ring
CC	0031965	cellular_component	nuclear membrane
CC	0048513	biological_process	animal organ development
CC	0048731	biological_process	system development
CC	0051028	biological_process	mRNA transport
CC	0072006	biological_process	nephron development
CD	0000776	cellular_component	kinetochore
CD	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
CD	0005515	molecular_function	protein binding
CD	0005635	cellular_component	nuclear envelope
CD	0005643	cellular_component	nuclear pore
CD	0005829	cellular_component	cytosol
CD	0006406	biological_process	mRNA export from nucleus
CD	0006606	biological_process	protein import into nucleus
CD	0006913	biological_process	nucleocytoplasmic transport
CD	0008585	biological_process	female gonad development
CD	0015031	biological_process	protein transport
CD	0016020	cellular_component	membrane
CD	0017056	molecular_function	structural constituent of nuclear pore
CD	0031080	cellular_component	nuclear pore outer ring
CD	0031965	cellular_component	nuclear membrane
CD	0034399	cellular_component	nuclear periphery
CD	0051028	biological_process	mRNA transport
CD	0051292	biological_process	nuclear pore complex assembly
CD	0072006	biological_process	nephron development
CF	0000776	cellular_component	kinetochore
CF	0005198	molecular_function	structural molecule activity
CF	0005515	molecular_function	protein binding
CF	0005635	cellular_component	nuclear envelope
CF	0005643	cellular_component	nuclear pore
CF	0005654	cellular_component	nucleoplasm
CF	0005765	cellular_component	lysosomal membrane
CF	0005783	cellular_component	endoplasmic reticulum
CF	0005789	cellular_component	endoplasmic reticulum membrane
CF	0005829	cellular_component	cytosol
CF	0006606	biological_process	protein import into nucleus
CF	0006886	biological_process	intracellular protein transport
CF	0006913	biological_process	nucleocytoplasmic transport
CF	0012507	cellular_component	ER to Golgi transport vesicle membrane
CF	0015031	biological_process	protein transport
CF	0016192	biological_process	vesicle-mediated transport
CF	0030127	cellular_component	COPII vesicle coat
CF	0031080	cellular_component	nuclear pore outer ring
CF	0031410	cellular_component	cytoplasmic vesicle
CF	0031669	biological_process	cellular response to nutrient levels
CF	0032008	biological_process	positive regulation of TOR signaling
CF	0032527	biological_process	protein exit from endoplasmic reticulum
CF	0042802	molecular_function	identical protein binding
CF	0051028	biological_process	mRNA transport
CF	0061700	cellular_component	GATOR2 complex
CF	0070062	cellular_component	extracellular exosome
CF	0070863	biological_process	positive regulation of protein exit from endoplasmic reticulum
CF	0090110	biological_process	COPII-coated vesicle cargo loading
CF	0090114	biological_process	COPII-coated vesicle budding
CF	1902953	biological_process	positive regulation of ER to Golgi vesicle-mediated transport
CF	1904262	biological_process	negative regulation of TORC1 signaling
CF	1904263	biological_process	positive regulation of TORC1 signaling
CG	0000776	cellular_component	kinetochore
CG	0005198	molecular_function	structural molecule activity
CG	0005515	molecular_function	protein binding
CG	0005635	cellular_component	nuclear envelope
CG	0005643	cellular_component	nuclear pore
CG	0005765	cellular_component	lysosomal membrane
CG	0005829	cellular_component	cytosol
CG	0006913	biological_process	nucleocytoplasmic transport
CG	0006999	biological_process	nuclear pore organization
CG	0007059	biological_process	chromosome segregation
CG	0007080	biological_process	mitotic metaphase chromosome alignment
CG	0015031	biological_process	protein transport
CG	0031080	cellular_component	nuclear pore outer ring
CG	0031503	biological_process	protein-containing complex localization
CG	0031669	biological_process	cellular response to nutrient levels
CG	0034198	biological_process	cellular response to amino acid starvation
CG	0035859	cellular_component	Seh1-associated complex
CG	0051028	biological_process	mRNA transport
CG	0051301	biological_process	cell division
CG	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
CG	0061700	cellular_component	GATOR2 complex
CG	1904262	biological_process	negative regulation of TORC1 signaling
CG	1904263	biological_process	positive regulation of TORC1 signaling
CH	0000776	cellular_component	kinetochore
CH	0005515	molecular_function	protein binding
CH	0005635	cellular_component	nuclear envelope
CH	0005643	cellular_component	nuclear pore
CH	0005654	cellular_component	nucleoplasm
CH	0005737	cellular_component	cytoplasm
CH	0005819	cellular_component	spindle
CH	0005829	cellular_component	cytosol
CH	0006406	biological_process	mRNA export from nucleus
CH	0006606	biological_process	protein import into nucleus
CH	0006913	biological_process	nucleocytoplasmic transport
CH	0015031	biological_process	protein transport
CH	0016020	cellular_component	membrane
CH	0017056	molecular_function	structural constituent of nuclear pore
CH	0031080	cellular_component	nuclear pore outer ring
CH	0031965	cellular_component	nuclear membrane
CH	0045893	biological_process	positive regulation of DNA-templated transcription
CH	0051028	biological_process	mRNA transport
CH	0072006	biological_process	nephron development
CI	0000776	cellular_component	kinetochore
CI	0005515	molecular_function	protein binding
CI	0005635	cellular_component	nuclear envelope
CI	0005643	cellular_component	nuclear pore
CI	0005654	cellular_component	nucleoplasm
CI	0005829	cellular_component	cytosol
CI	0006913	biological_process	nucleocytoplasmic transport
CI	0007059	biological_process	chromosome segregation
CI	0015031	biological_process	protein transport
CI	0031080	cellular_component	nuclear pore outer ring
CI	0051028	biological_process	mRNA transport
CI	0051301	biological_process	cell division
CJ	0000776	cellular_component	kinetochore
CJ	0005515	molecular_function	protein binding
CJ	0005635	cellular_component	nuclear envelope
CJ	0005643	cellular_component	nuclear pore
CJ	0005829	cellular_component	cytosol
CJ	0006406	biological_process	mRNA export from nucleus
CJ	0006913	biological_process	nucleocytoplasmic transport
CJ	0015031	biological_process	protein transport
CJ	0017056	molecular_function	structural constituent of nuclear pore
CJ	0031080	cellular_component	nuclear pore outer ring
CJ	0051028	biological_process	mRNA transport
CJ	0072006	biological_process	nephron development
CK	0000776	cellular_component	kinetochore
CK	0005515	molecular_function	protein binding
CK	0005634	cellular_component	nucleus
CK	0005635	cellular_component	nuclear envelope
CK	0005643	cellular_component	nuclear pore
CK	0005654	cellular_component	nucleoplasm
CK	0005829	cellular_component	cytosol
CK	0006913	biological_process	nucleocytoplasmic transport
CK	0007059	biological_process	chromosome segregation
CK	0015031	biological_process	protein transport
CK	0031080	cellular_component	nuclear pore outer ring
CK	0051028	biological_process	mRNA transport
CK	0051301	biological_process	cell division
DC	0000776	cellular_component	kinetochore
DC	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
DC	0005515	molecular_function	protein binding
DC	0005635	cellular_component	nuclear envelope
DC	0005643	cellular_component	nuclear pore
DC	0005829	cellular_component	cytosol
DC	0006406	biological_process	mRNA export from nucleus
DC	0006606	biological_process	protein import into nucleus
DC	0006913	biological_process	nucleocytoplasmic transport
DC	0006999	biological_process	nuclear pore organization
DC	0015031	biological_process	protein transport
DC	0016020	cellular_component	membrane
DC	0016973	biological_process	poly(A)+ mRNA export from nucleus
DC	0017056	molecular_function	structural constituent of nuclear pore
DC	0031080	cellular_component	nuclear pore outer ring
DC	0031965	cellular_component	nuclear membrane
DC	0048513	biological_process	animal organ development
DC	0048731	biological_process	system development
DC	0051028	biological_process	mRNA transport
DC	0072006	biological_process	nephron development
DD	0000776	cellular_component	kinetochore
DD	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
DD	0005515	molecular_function	protein binding
DD	0005635	cellular_component	nuclear envelope
DD	0005643	cellular_component	nuclear pore
DD	0005829	cellular_component	cytosol
DD	0006406	biological_process	mRNA export from nucleus
DD	0006606	biological_process	protein import into nucleus
DD	0006913	biological_process	nucleocytoplasmic transport
DD	0008585	biological_process	female gonad development
DD	0015031	biological_process	protein transport
DD	0016020	cellular_component	membrane
DD	0017056	molecular_function	structural constituent of nuclear pore
DD	0031080	cellular_component	nuclear pore outer ring
DD	0031965	cellular_component	nuclear membrane
DD	0034399	cellular_component	nuclear periphery
DD	0051028	biological_process	mRNA transport
DD	0051292	biological_process	nuclear pore complex assembly
DD	0072006	biological_process	nephron development
DF	0000776	cellular_component	kinetochore
DF	0005198	molecular_function	structural molecule activity
DF	0005515	molecular_function	protein binding
DF	0005635	cellular_component	nuclear envelope
DF	0005643	cellular_component	nuclear pore
DF	0005654	cellular_component	nucleoplasm
DF	0005765	cellular_component	lysosomal membrane
DF	0005783	cellular_component	endoplasmic reticulum
DF	0005789	cellular_component	endoplasmic reticulum membrane
DF	0005829	cellular_component	cytosol
DF	0006606	biological_process	protein import into nucleus
DF	0006886	biological_process	intracellular protein transport
DF	0006913	biological_process	nucleocytoplasmic transport
DF	0012507	cellular_component	ER to Golgi transport vesicle membrane
DF	0015031	biological_process	protein transport
DF	0016192	biological_process	vesicle-mediated transport
DF	0030127	cellular_component	COPII vesicle coat
DF	0031080	cellular_component	nuclear pore outer ring
DF	0031410	cellular_component	cytoplasmic vesicle
DF	0031669	biological_process	cellular response to nutrient levels
DF	0032008	biological_process	positive regulation of TOR signaling
DF	0032527	biological_process	protein exit from endoplasmic reticulum
DF	0042802	molecular_function	identical protein binding
DF	0051028	biological_process	mRNA transport
DF	0061700	cellular_component	GATOR2 complex
DF	0070062	cellular_component	extracellular exosome
DF	0070863	biological_process	positive regulation of protein exit from endoplasmic reticulum
DF	0090110	biological_process	COPII-coated vesicle cargo loading
DF	0090114	biological_process	COPII-coated vesicle budding
DF	1902953	biological_process	positive regulation of ER to Golgi vesicle-mediated transport
DF	1904262	biological_process	negative regulation of TORC1 signaling
DF	1904263	biological_process	positive regulation of TORC1 signaling
DG	0000776	cellular_component	kinetochore
DG	0005198	molecular_function	structural molecule activity
DG	0005515	molecular_function	protein binding
DG	0005635	cellular_component	nuclear envelope
DG	0005643	cellular_component	nuclear pore
DG	0005765	cellular_component	lysosomal membrane
DG	0005829	cellular_component	cytosol
DG	0006913	biological_process	nucleocytoplasmic transport
DG	0006999	biological_process	nuclear pore organization
DG	0007059	biological_process	chromosome segregation
DG	0007080	biological_process	mitotic metaphase chromosome alignment
DG	0015031	biological_process	protein transport
DG	0031080	cellular_component	nuclear pore outer ring
DG	0031503	biological_process	protein-containing complex localization
DG	0031669	biological_process	cellular response to nutrient levels
DG	0034198	biological_process	cellular response to amino acid starvation
DG	0035859	cellular_component	Seh1-associated complex
DG	0051028	biological_process	mRNA transport
DG	0051301	biological_process	cell division
DG	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
DG	0061700	cellular_component	GATOR2 complex
DG	1904262	biological_process	negative regulation of TORC1 signaling
DG	1904263	biological_process	positive regulation of TORC1 signaling
DH	0000776	cellular_component	kinetochore
DH	0005515	molecular_function	protein binding
DH	0005635	cellular_component	nuclear envelope
DH	0005643	cellular_component	nuclear pore
DH	0005654	cellular_component	nucleoplasm
DH	0005737	cellular_component	cytoplasm
DH	0005819	cellular_component	spindle
DH	0005829	cellular_component	cytosol
DH	0006406	biological_process	mRNA export from nucleus
DH	0006606	biological_process	protein import into nucleus
DH	0006913	biological_process	nucleocytoplasmic transport
DH	0015031	biological_process	protein transport
DH	0016020	cellular_component	membrane
DH	0017056	molecular_function	structural constituent of nuclear pore
DH	0031080	cellular_component	nuclear pore outer ring
DH	0031965	cellular_component	nuclear membrane
DH	0045893	biological_process	positive regulation of DNA-templated transcription
DH	0051028	biological_process	mRNA transport
DH	0072006	biological_process	nephron development
DI	0000776	cellular_component	kinetochore
DI	0005515	molecular_function	protein binding
DI	0005635	cellular_component	nuclear envelope
DI	0005643	cellular_component	nuclear pore
DI	0005654	cellular_component	nucleoplasm
DI	0005829	cellular_component	cytosol
DI	0006913	biological_process	nucleocytoplasmic transport
DI	0007059	biological_process	chromosome segregation
DI	0015031	biological_process	protein transport
DI	0031080	cellular_component	nuclear pore outer ring
DI	0051028	biological_process	mRNA transport
DI	0051301	biological_process	cell division
DJ	0000776	cellular_component	kinetochore
DJ	0005515	molecular_function	protein binding
DJ	0005635	cellular_component	nuclear envelope
DJ	0005643	cellular_component	nuclear pore
DJ	0005829	cellular_component	cytosol
DJ	0006406	biological_process	mRNA export from nucleus
DJ	0006913	biological_process	nucleocytoplasmic transport
DJ	0015031	biological_process	protein transport
DJ	0017056	molecular_function	structural constituent of nuclear pore
DJ	0031080	cellular_component	nuclear pore outer ring
DJ	0051028	biological_process	mRNA transport
DJ	0072006	biological_process	nephron development
DK	0000776	cellular_component	kinetochore
DK	0005515	molecular_function	protein binding
DK	0005634	cellular_component	nucleus
DK	0005635	cellular_component	nuclear envelope
DK	0005643	cellular_component	nuclear pore
DK	0005654	cellular_component	nucleoplasm
DK	0005829	cellular_component	cytosol
DK	0006913	biological_process	nucleocytoplasmic transport
DK	0007059	biological_process	chromosome segregation
DK	0015031	biological_process	protein transport
DK	0031080	cellular_component	nuclear pore outer ring
DK	0051028	biological_process	mRNA transport
DK	0051301	biological_process	cell division

Functional Information from PROSITE/UniProt

site_id	PS00616
Number of Residues	15
Details	HIS_ACID_PHOSPHAT_1 Histidine acid phosphatases phosphohistidine signature. LlyAfhIyRHNyRkA

Chain	Residue	Details
AJ	LEU1083-ALA1097

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. IASVsdDhTCRIWNL

Chain	Residue	Details
CK	ILE140-LEU154
AI	VAL233-VAL247

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q8R0G9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q6PFD9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q6PFD9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	672
Details	Repeat: {"description":"WD 2"}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	492
Details	Repeat: {"description":"WD 3"}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	648
Details	Repeat: {"description":"WD 5"}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	472
Details	Repeat: {"description":"WD 6"}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	20
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	156
Details	Repeat: {"description":"WD 1"}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	496
Details	Repeat: {"description":"WD 4"}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q8R480","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	148
Details	Repeat: {"description":"WD 7"}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)