Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7PEQ

Model of the outer rings of the human nuclear pore complex

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AC	0000775	cellular_component	chromosome, centromeric region
AC	0000776	cellular_component	kinetochore
AC	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
AC	0005515	molecular_function	protein binding
AC	0005634	cellular_component	nucleus
AC	0005635	cellular_component	nuclear envelope
AC	0005643	cellular_component	nuclear pore
AC	0005694	cellular_component	chromosome
AC	0005829	cellular_component	cytosol
AC	0006406	biological_process	mRNA export from nucleus
AC	0006606	biological_process	protein import into nucleus
AC	0006913	biological_process	nucleocytoplasmic transport
AC	0006999	biological_process	nuclear pore organization
AC	0015031	biological_process	protein transport
AC	0016020	cellular_component	membrane
AC	0016973	biological_process	poly(A)+ mRNA export from nucleus
AC	0017056	molecular_function	structural constituent of nuclear pore
AC	0021915	biological_process	neural tube development
AC	0022008	biological_process	neurogenesis
AC	0031080	cellular_component	nuclear pore outer ring
AC	0031965	cellular_component	nuclear membrane
AC	0048339	biological_process	paraxial mesoderm development
AC	0051028	biological_process	mRNA transport
AC	0061053	biological_process	somite development
AC	0072006	biological_process	nephron development
AD	0000775	cellular_component	chromosome, centromeric region
AD	0000776	cellular_component	kinetochore
AD	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
AD	0005515	molecular_function	protein binding
AD	0005634	cellular_component	nucleus
AD	0005635	cellular_component	nuclear envelope
AD	0005643	cellular_component	nuclear pore
AD	0005694	cellular_component	chromosome
AD	0005829	cellular_component	cytosol
AD	0006406	biological_process	mRNA export from nucleus
AD	0006606	biological_process	protein import into nucleus
AD	0006913	biological_process	nucleocytoplasmic transport
AD	0008585	biological_process	female gonad development
AD	0015031	biological_process	protein transport
AD	0016020	cellular_component	membrane
AD	0017056	molecular_function	structural constituent of nuclear pore
AD	0031080	cellular_component	nuclear pore outer ring
AD	0031965	cellular_component	nuclear membrane
AD	0034399	cellular_component	nuclear periphery
AD	0051028	biological_process	mRNA transport
AD	0051292	biological_process	nuclear pore complex assembly
AD	0072006	biological_process	nephron development
AF	0000776	cellular_component	kinetochore
AF	0005198	molecular_function	structural molecule activity
AF	0005515	molecular_function	protein binding
AF	0005634	cellular_component	nucleus
AF	0005635	cellular_component	nuclear envelope
AF	0005643	cellular_component	nuclear pore
AF	0005654	cellular_component	nucleoplasm
AF	0005764	cellular_component	lysosome
AF	0005765	cellular_component	lysosomal membrane
AF	0005783	cellular_component	endoplasmic reticulum
AF	0005789	cellular_component	endoplasmic reticulum membrane
AF	0005829	cellular_component	cytosol
AF	0006606	biological_process	protein import into nucleus
AF	0006886	biological_process	intracellular protein transport
AF	0006913	biological_process	nucleocytoplasmic transport
AF	0012507	cellular_component	ER to Golgi transport vesicle membrane
AF	0015031	biological_process	protein transport
AF	0016020	cellular_component	membrane
AF	0016192	biological_process	vesicle-mediated transport
AF	0030127	cellular_component	COPII vesicle coat
AF	0031080	cellular_component	nuclear pore outer ring
AF	0031410	cellular_component	cytoplasmic vesicle
AF	0031669	biological_process	cellular response to nutrient levels
AF	0032008	biological_process	positive regulation of TOR signaling
AF	0032527	biological_process	protein exit from endoplasmic reticulum
AF	0042802	molecular_function	identical protein binding
AF	0043231	cellular_component	intracellular membrane-bounded organelle
AF	0051028	biological_process	mRNA transport
AF	0061700	cellular_component	GATOR2 complex
AF	0070062	cellular_component	extracellular exosome
AF	0090110	biological_process	COPII-coated vesicle cargo loading
AF	0090114	biological_process	COPII-coated vesicle budding
AF	1904262	biological_process	negative regulation of TORC1 signaling
AF	1904263	biological_process	positive regulation of TORC1 signaling
AG	0000775	cellular_component	chromosome, centromeric region
AG	0000776	cellular_component	kinetochore
AG	0005198	molecular_function	structural molecule activity
AG	0005515	molecular_function	protein binding
AG	0005634	cellular_component	nucleus
AG	0005635	cellular_component	nuclear envelope
AG	0005643	cellular_component	nuclear pore
AG	0005694	cellular_component	chromosome
AG	0005764	cellular_component	lysosome
AG	0005765	cellular_component	lysosomal membrane
AG	0005829	cellular_component	cytosol
AG	0006913	biological_process	nucleocytoplasmic transport
AG	0006999	biological_process	nuclear pore organization
AG	0007059	biological_process	chromosome segregation
AG	0007080	biological_process	mitotic metaphase chromosome alignment
AG	0015031	biological_process	protein transport
AG	0016020	cellular_component	membrane
AG	0031080	cellular_component	nuclear pore outer ring
AG	0031503	biological_process	protein-containing complex localization
AG	0031669	biological_process	cellular response to nutrient levels
AG	0034198	biological_process	cellular response to amino acid starvation
AG	0035859	cellular_component	Seh1-associated complex
AG	0050830	biological_process	defense response to Gram-positive bacterium
AG	0051028	biological_process	mRNA transport
AG	0051301	biological_process	cell division
AG	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
AG	0061700	cellular_component	GATOR2 complex
AG	1904262	biological_process	negative regulation of TORC1 signaling
AG	1904263	biological_process	positive regulation of TORC1 signaling
AH	0000775	cellular_component	chromosome, centromeric region
AH	0000776	cellular_component	kinetochore
AH	0005515	molecular_function	protein binding
AH	0005634	cellular_component	nucleus
AH	0005635	cellular_component	nuclear envelope
AH	0005643	cellular_component	nuclear pore
AH	0005654	cellular_component	nucleoplasm
AH	0005694	cellular_component	chromosome
AH	0005737	cellular_component	cytoplasm
AH	0005819	cellular_component	spindle
AH	0005829	cellular_component	cytosol
AH	0005856	cellular_component	cytoskeleton
AH	0006406	biological_process	mRNA export from nucleus
AH	0006606	biological_process	protein import into nucleus
AH	0006913	biological_process	nucleocytoplasmic transport
AH	0006935	biological_process	chemotaxis
AH	0015031	biological_process	protein transport
AH	0016020	cellular_component	membrane
AH	0017056	molecular_function	structural constituent of nuclear pore
AH	0030032	biological_process	lamellipodium assembly
AH	0031080	cellular_component	nuclear pore outer ring
AH	0031965	cellular_component	nuclear membrane
AH	0045893	biological_process	positive regulation of DNA-templated transcription
AH	0048246	biological_process	macrophage chemotaxis
AH	0051028	biological_process	mRNA transport
AH	0072006	biological_process	nephron development
AI	0000775	cellular_component	chromosome, centromeric region
AI	0000776	cellular_component	kinetochore
AI	0005515	molecular_function	protein binding
AI	0005634	cellular_component	nucleus
AI	0005635	cellular_component	nuclear envelope
AI	0005643	cellular_component	nuclear pore
AI	0005654	cellular_component	nucleoplasm
AI	0005694	cellular_component	chromosome
AI	0005829	cellular_component	cytosol
AI	0006913	biological_process	nucleocytoplasmic transport
AI	0007059	biological_process	chromosome segregation
AI	0015031	biological_process	protein transport
AI	0016607	cellular_component	nuclear speck
AI	0031080	cellular_component	nuclear pore outer ring
AI	0051028	biological_process	mRNA transport
AI	0051301	biological_process	cell division
AJ	0000776	cellular_component	kinetochore
AJ	0005515	molecular_function	protein binding
AJ	0005634	cellular_component	nucleus
AJ	0005635	cellular_component	nuclear envelope
AJ	0005643	cellular_component	nuclear pore
AJ	0005829	cellular_component	cytosol
AJ	0006406	biological_process	mRNA export from nucleus
AJ	0006913	biological_process	nucleocytoplasmic transport
AJ	0015031	biological_process	protein transport
AJ	0017056	molecular_function	structural constituent of nuclear pore
AJ	0031080	cellular_component	nuclear pore outer ring
AJ	0033036	biological_process	macromolecule localization
AJ	0051028	biological_process	mRNA transport
AJ	0071705	biological_process	nitrogen compound transport
AJ	0072006	biological_process	nephron development
AK	0000775	cellular_component	chromosome, centromeric region
AK	0000776	cellular_component	kinetochore
AK	0005515	molecular_function	protein binding
AK	0005634	cellular_component	nucleus
AK	0005635	cellular_component	nuclear envelope
AK	0005643	cellular_component	nuclear pore
AK	0005654	cellular_component	nucleoplasm
AK	0005694	cellular_component	chromosome
AK	0005829	cellular_component	cytosol
AK	0006913	biological_process	nucleocytoplasmic transport
AK	0007059	biological_process	chromosome segregation
AK	0015031	biological_process	protein transport
AK	0031080	cellular_component	nuclear pore outer ring
AK	0051028	biological_process	mRNA transport
AK	0051301	biological_process	cell division
BC	0000775	cellular_component	chromosome, centromeric region
BC	0000776	cellular_component	kinetochore
BC	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
BC	0005515	molecular_function	protein binding
BC	0005634	cellular_component	nucleus
BC	0005635	cellular_component	nuclear envelope
BC	0005643	cellular_component	nuclear pore
BC	0005694	cellular_component	chromosome
BC	0005829	cellular_component	cytosol
BC	0006406	biological_process	mRNA export from nucleus
BC	0006606	biological_process	protein import into nucleus
BC	0006913	biological_process	nucleocytoplasmic transport
BC	0006999	biological_process	nuclear pore organization
BC	0015031	biological_process	protein transport
BC	0016020	cellular_component	membrane
BC	0016973	biological_process	poly(A)+ mRNA export from nucleus
BC	0017056	molecular_function	structural constituent of nuclear pore
BC	0021915	biological_process	neural tube development
BC	0022008	biological_process	neurogenesis
BC	0031080	cellular_component	nuclear pore outer ring
BC	0031965	cellular_component	nuclear membrane
BC	0048339	biological_process	paraxial mesoderm development
BC	0051028	biological_process	mRNA transport
BC	0061053	biological_process	somite development
BC	0072006	biological_process	nephron development
BD	0000775	cellular_component	chromosome, centromeric region
BD	0000776	cellular_component	kinetochore
BD	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
BD	0005515	molecular_function	protein binding
BD	0005634	cellular_component	nucleus
BD	0005635	cellular_component	nuclear envelope
BD	0005643	cellular_component	nuclear pore
BD	0005694	cellular_component	chromosome
BD	0005829	cellular_component	cytosol
BD	0006406	biological_process	mRNA export from nucleus
BD	0006606	biological_process	protein import into nucleus
BD	0006913	biological_process	nucleocytoplasmic transport
BD	0008585	biological_process	female gonad development
BD	0015031	biological_process	protein transport
BD	0016020	cellular_component	membrane
BD	0017056	molecular_function	structural constituent of nuclear pore
BD	0031080	cellular_component	nuclear pore outer ring
BD	0031965	cellular_component	nuclear membrane
BD	0034399	cellular_component	nuclear periphery
BD	0051028	biological_process	mRNA transport
BD	0051292	biological_process	nuclear pore complex assembly
BD	0072006	biological_process	nephron development
BF	0000776	cellular_component	kinetochore
BF	0005198	molecular_function	structural molecule activity
BF	0005515	molecular_function	protein binding
BF	0005634	cellular_component	nucleus
BF	0005635	cellular_component	nuclear envelope
BF	0005643	cellular_component	nuclear pore
BF	0005654	cellular_component	nucleoplasm
BF	0005764	cellular_component	lysosome
BF	0005765	cellular_component	lysosomal membrane
BF	0005783	cellular_component	endoplasmic reticulum
BF	0005789	cellular_component	endoplasmic reticulum membrane
BF	0005829	cellular_component	cytosol
BF	0006606	biological_process	protein import into nucleus
BF	0006886	biological_process	intracellular protein transport
BF	0006913	biological_process	nucleocytoplasmic transport
BF	0012507	cellular_component	ER to Golgi transport vesicle membrane
BF	0015031	biological_process	protein transport
BF	0016020	cellular_component	membrane
BF	0016192	biological_process	vesicle-mediated transport
BF	0030127	cellular_component	COPII vesicle coat
BF	0031080	cellular_component	nuclear pore outer ring
BF	0031410	cellular_component	cytoplasmic vesicle
BF	0031669	biological_process	cellular response to nutrient levels
BF	0032008	biological_process	positive regulation of TOR signaling
BF	0032527	biological_process	protein exit from endoplasmic reticulum
BF	0042802	molecular_function	identical protein binding
BF	0043231	cellular_component	intracellular membrane-bounded organelle
BF	0051028	biological_process	mRNA transport
BF	0061700	cellular_component	GATOR2 complex
BF	0070062	cellular_component	extracellular exosome
BF	0090110	biological_process	COPII-coated vesicle cargo loading
BF	0090114	biological_process	COPII-coated vesicle budding
BF	1904262	biological_process	negative regulation of TORC1 signaling
BF	1904263	biological_process	positive regulation of TORC1 signaling
BG	0000775	cellular_component	chromosome, centromeric region
BG	0000776	cellular_component	kinetochore
BG	0005198	molecular_function	structural molecule activity
BG	0005515	molecular_function	protein binding
BG	0005634	cellular_component	nucleus
BG	0005635	cellular_component	nuclear envelope
BG	0005643	cellular_component	nuclear pore
BG	0005694	cellular_component	chromosome
BG	0005764	cellular_component	lysosome
BG	0005765	cellular_component	lysosomal membrane
BG	0005829	cellular_component	cytosol
BG	0006913	biological_process	nucleocytoplasmic transport
BG	0006999	biological_process	nuclear pore organization
BG	0007059	biological_process	chromosome segregation
BG	0007080	biological_process	mitotic metaphase chromosome alignment
BG	0015031	biological_process	protein transport
BG	0016020	cellular_component	membrane
BG	0031080	cellular_component	nuclear pore outer ring
BG	0031503	biological_process	protein-containing complex localization
BG	0031669	biological_process	cellular response to nutrient levels
BG	0034198	biological_process	cellular response to amino acid starvation
BG	0035859	cellular_component	Seh1-associated complex
BG	0050830	biological_process	defense response to Gram-positive bacterium
BG	0051028	biological_process	mRNA transport
BG	0051301	biological_process	cell division
BG	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
BG	0061700	cellular_component	GATOR2 complex
BG	1904262	biological_process	negative regulation of TORC1 signaling
BG	1904263	biological_process	positive regulation of TORC1 signaling
BH	0000775	cellular_component	chromosome, centromeric region
BH	0000776	cellular_component	kinetochore
BH	0005515	molecular_function	protein binding
BH	0005634	cellular_component	nucleus
BH	0005635	cellular_component	nuclear envelope
BH	0005643	cellular_component	nuclear pore
BH	0005654	cellular_component	nucleoplasm
BH	0005694	cellular_component	chromosome
BH	0005737	cellular_component	cytoplasm
BH	0005819	cellular_component	spindle
BH	0005829	cellular_component	cytosol
BH	0005856	cellular_component	cytoskeleton
BH	0006406	biological_process	mRNA export from nucleus
BH	0006606	biological_process	protein import into nucleus
BH	0006913	biological_process	nucleocytoplasmic transport
BH	0006935	biological_process	chemotaxis
BH	0015031	biological_process	protein transport
BH	0016020	cellular_component	membrane
BH	0017056	molecular_function	structural constituent of nuclear pore
BH	0030032	biological_process	lamellipodium assembly
BH	0031080	cellular_component	nuclear pore outer ring
BH	0031965	cellular_component	nuclear membrane
BH	0045893	biological_process	positive regulation of DNA-templated transcription
BH	0048246	biological_process	macrophage chemotaxis
BH	0051028	biological_process	mRNA transport
BH	0072006	biological_process	nephron development
BI	0000775	cellular_component	chromosome, centromeric region
BI	0000776	cellular_component	kinetochore
BI	0005515	molecular_function	protein binding
BI	0005634	cellular_component	nucleus
BI	0005635	cellular_component	nuclear envelope
BI	0005643	cellular_component	nuclear pore
BI	0005654	cellular_component	nucleoplasm
BI	0005694	cellular_component	chromosome
BI	0005829	cellular_component	cytosol
BI	0006913	biological_process	nucleocytoplasmic transport
BI	0007059	biological_process	chromosome segregation
BI	0015031	biological_process	protein transport
BI	0016607	cellular_component	nuclear speck
BI	0031080	cellular_component	nuclear pore outer ring
BI	0051028	biological_process	mRNA transport
BI	0051301	biological_process	cell division
BJ	0000776	cellular_component	kinetochore
BJ	0005515	molecular_function	protein binding
BJ	0005634	cellular_component	nucleus
BJ	0005635	cellular_component	nuclear envelope
BJ	0005643	cellular_component	nuclear pore
BJ	0005829	cellular_component	cytosol
BJ	0006406	biological_process	mRNA export from nucleus
BJ	0006913	biological_process	nucleocytoplasmic transport
BJ	0015031	biological_process	protein transport
BJ	0017056	molecular_function	structural constituent of nuclear pore
BJ	0031080	cellular_component	nuclear pore outer ring
BJ	0033036	biological_process	macromolecule localization
BJ	0051028	biological_process	mRNA transport
BJ	0071705	biological_process	nitrogen compound transport
BJ	0072006	biological_process	nephron development
BK	0000775	cellular_component	chromosome, centromeric region
BK	0000776	cellular_component	kinetochore
BK	0005515	molecular_function	protein binding
BK	0005634	cellular_component	nucleus
BK	0005635	cellular_component	nuclear envelope
BK	0005643	cellular_component	nuclear pore
BK	0005654	cellular_component	nucleoplasm
BK	0005694	cellular_component	chromosome
BK	0005829	cellular_component	cytosol
BK	0006913	biological_process	nucleocytoplasmic transport
BK	0007059	biological_process	chromosome segregation
BK	0015031	biological_process	protein transport
BK	0031080	cellular_component	nuclear pore outer ring
BK	0051028	biological_process	mRNA transport
BK	0051301	biological_process	cell division
CC	0000775	cellular_component	chromosome, centromeric region
CC	0000776	cellular_component	kinetochore
CC	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
CC	0005515	molecular_function	protein binding
CC	0005634	cellular_component	nucleus
CC	0005635	cellular_component	nuclear envelope
CC	0005643	cellular_component	nuclear pore
CC	0005694	cellular_component	chromosome
CC	0005829	cellular_component	cytosol
CC	0006406	biological_process	mRNA export from nucleus
CC	0006606	biological_process	protein import into nucleus
CC	0006913	biological_process	nucleocytoplasmic transport
CC	0006999	biological_process	nuclear pore organization
CC	0015031	biological_process	protein transport
CC	0016020	cellular_component	membrane
CC	0016973	biological_process	poly(A)+ mRNA export from nucleus
CC	0017056	molecular_function	structural constituent of nuclear pore
CC	0021915	biological_process	neural tube development
CC	0022008	biological_process	neurogenesis
CC	0031080	cellular_component	nuclear pore outer ring
CC	0031965	cellular_component	nuclear membrane
CC	0048339	biological_process	paraxial mesoderm development
CC	0051028	biological_process	mRNA transport
CC	0061053	biological_process	somite development
CC	0072006	biological_process	nephron development
CD	0000775	cellular_component	chromosome, centromeric region
CD	0000776	cellular_component	kinetochore
CD	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
CD	0005515	molecular_function	protein binding
CD	0005634	cellular_component	nucleus
CD	0005635	cellular_component	nuclear envelope
CD	0005643	cellular_component	nuclear pore
CD	0005694	cellular_component	chromosome
CD	0005829	cellular_component	cytosol
CD	0006406	biological_process	mRNA export from nucleus
CD	0006606	biological_process	protein import into nucleus
CD	0006913	biological_process	nucleocytoplasmic transport
CD	0008585	biological_process	female gonad development
CD	0015031	biological_process	protein transport
CD	0016020	cellular_component	membrane
CD	0017056	molecular_function	structural constituent of nuclear pore
CD	0031080	cellular_component	nuclear pore outer ring
CD	0031965	cellular_component	nuclear membrane
CD	0034399	cellular_component	nuclear periphery
CD	0051028	biological_process	mRNA transport
CD	0051292	biological_process	nuclear pore complex assembly
CD	0072006	biological_process	nephron development
CF	0000776	cellular_component	kinetochore
CF	0005198	molecular_function	structural molecule activity
CF	0005515	molecular_function	protein binding
CF	0005634	cellular_component	nucleus
CF	0005635	cellular_component	nuclear envelope
CF	0005643	cellular_component	nuclear pore
CF	0005654	cellular_component	nucleoplasm
CF	0005764	cellular_component	lysosome
CF	0005765	cellular_component	lysosomal membrane
CF	0005783	cellular_component	endoplasmic reticulum
CF	0005789	cellular_component	endoplasmic reticulum membrane
CF	0005829	cellular_component	cytosol
CF	0006606	biological_process	protein import into nucleus
CF	0006886	biological_process	intracellular protein transport
CF	0006913	biological_process	nucleocytoplasmic transport
CF	0012507	cellular_component	ER to Golgi transport vesicle membrane
CF	0015031	biological_process	protein transport
CF	0016020	cellular_component	membrane
CF	0016192	biological_process	vesicle-mediated transport
CF	0030127	cellular_component	COPII vesicle coat
CF	0031080	cellular_component	nuclear pore outer ring
CF	0031410	cellular_component	cytoplasmic vesicle
CF	0031669	biological_process	cellular response to nutrient levels
CF	0032008	biological_process	positive regulation of TOR signaling
CF	0032527	biological_process	protein exit from endoplasmic reticulum
CF	0042802	molecular_function	identical protein binding
CF	0043231	cellular_component	intracellular membrane-bounded organelle
CF	0051028	biological_process	mRNA transport
CF	0061700	cellular_component	GATOR2 complex
CF	0070062	cellular_component	extracellular exosome
CF	0090110	biological_process	COPII-coated vesicle cargo loading
CF	0090114	biological_process	COPII-coated vesicle budding
CF	1904262	biological_process	negative regulation of TORC1 signaling
CF	1904263	biological_process	positive regulation of TORC1 signaling
CG	0000775	cellular_component	chromosome, centromeric region
CG	0000776	cellular_component	kinetochore
CG	0005198	molecular_function	structural molecule activity
CG	0005515	molecular_function	protein binding
CG	0005634	cellular_component	nucleus
CG	0005635	cellular_component	nuclear envelope
CG	0005643	cellular_component	nuclear pore
CG	0005694	cellular_component	chromosome
CG	0005764	cellular_component	lysosome
CG	0005765	cellular_component	lysosomal membrane
CG	0005829	cellular_component	cytosol
CG	0006913	biological_process	nucleocytoplasmic transport
CG	0006999	biological_process	nuclear pore organization
CG	0007059	biological_process	chromosome segregation
CG	0007080	biological_process	mitotic metaphase chromosome alignment
CG	0015031	biological_process	protein transport
CG	0016020	cellular_component	membrane
CG	0031080	cellular_component	nuclear pore outer ring
CG	0031503	biological_process	protein-containing complex localization
CG	0031669	biological_process	cellular response to nutrient levels
CG	0034198	biological_process	cellular response to amino acid starvation
CG	0035859	cellular_component	Seh1-associated complex
CG	0050830	biological_process	defense response to Gram-positive bacterium
CG	0051028	biological_process	mRNA transport
CG	0051301	biological_process	cell division
CG	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
CG	0061700	cellular_component	GATOR2 complex
CG	1904262	biological_process	negative regulation of TORC1 signaling
CG	1904263	biological_process	positive regulation of TORC1 signaling
CH	0000775	cellular_component	chromosome, centromeric region
CH	0000776	cellular_component	kinetochore
CH	0005515	molecular_function	protein binding
CH	0005634	cellular_component	nucleus
CH	0005635	cellular_component	nuclear envelope
CH	0005643	cellular_component	nuclear pore
CH	0005654	cellular_component	nucleoplasm
CH	0005694	cellular_component	chromosome
CH	0005737	cellular_component	cytoplasm
CH	0005819	cellular_component	spindle
CH	0005829	cellular_component	cytosol
CH	0005856	cellular_component	cytoskeleton
CH	0006406	biological_process	mRNA export from nucleus
CH	0006606	biological_process	protein import into nucleus
CH	0006913	biological_process	nucleocytoplasmic transport
CH	0006935	biological_process	chemotaxis
CH	0015031	biological_process	protein transport
CH	0016020	cellular_component	membrane
CH	0017056	molecular_function	structural constituent of nuclear pore
CH	0030032	biological_process	lamellipodium assembly
CH	0031080	cellular_component	nuclear pore outer ring
CH	0031965	cellular_component	nuclear membrane
CH	0045893	biological_process	positive regulation of DNA-templated transcription
CH	0048246	biological_process	macrophage chemotaxis
CH	0051028	biological_process	mRNA transport
CH	0072006	biological_process	nephron development
CI	0000775	cellular_component	chromosome, centromeric region
CI	0000776	cellular_component	kinetochore
CI	0005515	molecular_function	protein binding
CI	0005634	cellular_component	nucleus
CI	0005635	cellular_component	nuclear envelope
CI	0005643	cellular_component	nuclear pore
CI	0005654	cellular_component	nucleoplasm
CI	0005694	cellular_component	chromosome
CI	0005829	cellular_component	cytosol
CI	0006913	biological_process	nucleocytoplasmic transport
CI	0007059	biological_process	chromosome segregation
CI	0015031	biological_process	protein transport
CI	0016607	cellular_component	nuclear speck
CI	0031080	cellular_component	nuclear pore outer ring
CI	0051028	biological_process	mRNA transport
CI	0051301	biological_process	cell division
CJ	0000776	cellular_component	kinetochore
CJ	0005515	molecular_function	protein binding
CJ	0005634	cellular_component	nucleus
CJ	0005635	cellular_component	nuclear envelope
CJ	0005643	cellular_component	nuclear pore
CJ	0005829	cellular_component	cytosol
CJ	0006406	biological_process	mRNA export from nucleus
CJ	0006913	biological_process	nucleocytoplasmic transport
CJ	0015031	biological_process	protein transport
CJ	0017056	molecular_function	structural constituent of nuclear pore
CJ	0031080	cellular_component	nuclear pore outer ring
CJ	0033036	biological_process	macromolecule localization
CJ	0051028	biological_process	mRNA transport
CJ	0071705	biological_process	nitrogen compound transport
CJ	0072006	biological_process	nephron development
CK	0000775	cellular_component	chromosome, centromeric region
CK	0000776	cellular_component	kinetochore
CK	0005515	molecular_function	protein binding
CK	0005634	cellular_component	nucleus
CK	0005635	cellular_component	nuclear envelope
CK	0005643	cellular_component	nuclear pore
CK	0005654	cellular_component	nucleoplasm
CK	0005694	cellular_component	chromosome
CK	0005829	cellular_component	cytosol
CK	0006913	biological_process	nucleocytoplasmic transport
CK	0007059	biological_process	chromosome segregation
CK	0015031	biological_process	protein transport
CK	0031080	cellular_component	nuclear pore outer ring
CK	0051028	biological_process	mRNA transport
CK	0051301	biological_process	cell division
DC	0000775	cellular_component	chromosome, centromeric region
DC	0000776	cellular_component	kinetochore
DC	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
DC	0005515	molecular_function	protein binding
DC	0005634	cellular_component	nucleus
DC	0005635	cellular_component	nuclear envelope
DC	0005643	cellular_component	nuclear pore
DC	0005694	cellular_component	chromosome
DC	0005829	cellular_component	cytosol
DC	0006406	biological_process	mRNA export from nucleus
DC	0006606	biological_process	protein import into nucleus
DC	0006913	biological_process	nucleocytoplasmic transport
DC	0006999	biological_process	nuclear pore organization
DC	0015031	biological_process	protein transport
DC	0016020	cellular_component	membrane
DC	0016973	biological_process	poly(A)+ mRNA export from nucleus
DC	0017056	molecular_function	structural constituent of nuclear pore
DC	0021915	biological_process	neural tube development
DC	0022008	biological_process	neurogenesis
DC	0031080	cellular_component	nuclear pore outer ring
DC	0031965	cellular_component	nuclear membrane
DC	0048339	biological_process	paraxial mesoderm development
DC	0051028	biological_process	mRNA transport
DC	0061053	biological_process	somite development
DC	0072006	biological_process	nephron development
DD	0000775	cellular_component	chromosome, centromeric region
DD	0000776	cellular_component	kinetochore
DD	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
DD	0005515	molecular_function	protein binding
DD	0005634	cellular_component	nucleus
DD	0005635	cellular_component	nuclear envelope
DD	0005643	cellular_component	nuclear pore
DD	0005694	cellular_component	chromosome
DD	0005829	cellular_component	cytosol
DD	0006406	biological_process	mRNA export from nucleus
DD	0006606	biological_process	protein import into nucleus
DD	0006913	biological_process	nucleocytoplasmic transport
DD	0008585	biological_process	female gonad development
DD	0015031	biological_process	protein transport
DD	0016020	cellular_component	membrane
DD	0017056	molecular_function	structural constituent of nuclear pore
DD	0031080	cellular_component	nuclear pore outer ring
DD	0031965	cellular_component	nuclear membrane
DD	0034399	cellular_component	nuclear periphery
DD	0051028	biological_process	mRNA transport
DD	0051292	biological_process	nuclear pore complex assembly
DD	0072006	biological_process	nephron development
DF	0000776	cellular_component	kinetochore
DF	0005198	molecular_function	structural molecule activity
DF	0005515	molecular_function	protein binding
DF	0005634	cellular_component	nucleus
DF	0005635	cellular_component	nuclear envelope
DF	0005643	cellular_component	nuclear pore
DF	0005654	cellular_component	nucleoplasm
DF	0005764	cellular_component	lysosome
DF	0005765	cellular_component	lysosomal membrane
DF	0005783	cellular_component	endoplasmic reticulum
DF	0005789	cellular_component	endoplasmic reticulum membrane
DF	0005829	cellular_component	cytosol
DF	0006606	biological_process	protein import into nucleus
DF	0006886	biological_process	intracellular protein transport
DF	0006913	biological_process	nucleocytoplasmic transport
DF	0012507	cellular_component	ER to Golgi transport vesicle membrane
DF	0015031	biological_process	protein transport
DF	0016020	cellular_component	membrane
DF	0016192	biological_process	vesicle-mediated transport
DF	0030127	cellular_component	COPII vesicle coat
DF	0031080	cellular_component	nuclear pore outer ring
DF	0031410	cellular_component	cytoplasmic vesicle
DF	0031669	biological_process	cellular response to nutrient levels
DF	0032008	biological_process	positive regulation of TOR signaling
DF	0032527	biological_process	protein exit from endoplasmic reticulum
DF	0042802	molecular_function	identical protein binding
DF	0043231	cellular_component	intracellular membrane-bounded organelle
DF	0051028	biological_process	mRNA transport
DF	0061700	cellular_component	GATOR2 complex
DF	0070062	cellular_component	extracellular exosome
DF	0090110	biological_process	COPII-coated vesicle cargo loading
DF	0090114	biological_process	COPII-coated vesicle budding
DF	1904262	biological_process	negative regulation of TORC1 signaling
DF	1904263	biological_process	positive regulation of TORC1 signaling
DG	0000775	cellular_component	chromosome, centromeric region
DG	0000776	cellular_component	kinetochore
DG	0005198	molecular_function	structural molecule activity
DG	0005515	molecular_function	protein binding
DG	0005634	cellular_component	nucleus
DG	0005635	cellular_component	nuclear envelope
DG	0005643	cellular_component	nuclear pore
DG	0005694	cellular_component	chromosome
DG	0005764	cellular_component	lysosome
DG	0005765	cellular_component	lysosomal membrane
DG	0005829	cellular_component	cytosol
DG	0006913	biological_process	nucleocytoplasmic transport
DG	0006999	biological_process	nuclear pore organization
DG	0007059	biological_process	chromosome segregation
DG	0007080	biological_process	mitotic metaphase chromosome alignment
DG	0015031	biological_process	protein transport
DG	0016020	cellular_component	membrane
DG	0031080	cellular_component	nuclear pore outer ring
DG	0031503	biological_process	protein-containing complex localization
DG	0031669	biological_process	cellular response to nutrient levels
DG	0034198	biological_process	cellular response to amino acid starvation
DG	0035859	cellular_component	Seh1-associated complex
DG	0050830	biological_process	defense response to Gram-positive bacterium
DG	0051028	biological_process	mRNA transport
DG	0051301	biological_process	cell division
DG	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
DG	0061700	cellular_component	GATOR2 complex
DG	1904262	biological_process	negative regulation of TORC1 signaling
DG	1904263	biological_process	positive regulation of TORC1 signaling
DH	0000775	cellular_component	chromosome, centromeric region
DH	0000776	cellular_component	kinetochore
DH	0005515	molecular_function	protein binding
DH	0005634	cellular_component	nucleus
DH	0005635	cellular_component	nuclear envelope
DH	0005643	cellular_component	nuclear pore
DH	0005654	cellular_component	nucleoplasm
DH	0005694	cellular_component	chromosome
DH	0005737	cellular_component	cytoplasm
DH	0005819	cellular_component	spindle
DH	0005829	cellular_component	cytosol
DH	0005856	cellular_component	cytoskeleton
DH	0006406	biological_process	mRNA export from nucleus
DH	0006606	biological_process	protein import into nucleus
DH	0006913	biological_process	nucleocytoplasmic transport
DH	0006935	biological_process	chemotaxis
DH	0015031	biological_process	protein transport
DH	0016020	cellular_component	membrane
DH	0017056	molecular_function	structural constituent of nuclear pore
DH	0030032	biological_process	lamellipodium assembly
DH	0031080	cellular_component	nuclear pore outer ring
DH	0031965	cellular_component	nuclear membrane
DH	0045893	biological_process	positive regulation of DNA-templated transcription
DH	0048246	biological_process	macrophage chemotaxis
DH	0051028	biological_process	mRNA transport
DH	0072006	biological_process	nephron development
DI	0000775	cellular_component	chromosome, centromeric region
DI	0000776	cellular_component	kinetochore
DI	0005515	molecular_function	protein binding
DI	0005634	cellular_component	nucleus
DI	0005635	cellular_component	nuclear envelope
DI	0005643	cellular_component	nuclear pore
DI	0005654	cellular_component	nucleoplasm
DI	0005694	cellular_component	chromosome
DI	0005829	cellular_component	cytosol
DI	0006913	biological_process	nucleocytoplasmic transport
DI	0007059	biological_process	chromosome segregation
DI	0015031	biological_process	protein transport
DI	0016607	cellular_component	nuclear speck
DI	0031080	cellular_component	nuclear pore outer ring
DI	0051028	biological_process	mRNA transport
DI	0051301	biological_process	cell division
DJ	0000776	cellular_component	kinetochore
DJ	0005515	molecular_function	protein binding
DJ	0005634	cellular_component	nucleus
DJ	0005635	cellular_component	nuclear envelope
DJ	0005643	cellular_component	nuclear pore
DJ	0005829	cellular_component	cytosol
DJ	0006406	biological_process	mRNA export from nucleus
DJ	0006913	biological_process	nucleocytoplasmic transport
DJ	0015031	biological_process	protein transport
DJ	0017056	molecular_function	structural constituent of nuclear pore
DJ	0031080	cellular_component	nuclear pore outer ring
DJ	0033036	biological_process	macromolecule localization
DJ	0051028	biological_process	mRNA transport
DJ	0071705	biological_process	nitrogen compound transport
DJ	0072006	biological_process	nephron development
DK	0000775	cellular_component	chromosome, centromeric region
DK	0000776	cellular_component	kinetochore
DK	0005515	molecular_function	protein binding
DK	0005634	cellular_component	nucleus
DK	0005635	cellular_component	nuclear envelope
DK	0005643	cellular_component	nuclear pore
DK	0005654	cellular_component	nucleoplasm
DK	0005694	cellular_component	chromosome
DK	0005829	cellular_component	cytosol
DK	0006913	biological_process	nucleocytoplasmic transport
DK	0007059	biological_process	chromosome segregation
DK	0015031	biological_process	protein transport
DK	0031080	cellular_component	nuclear pore outer ring
DK	0051028	biological_process	mRNA transport
DK	0051301	biological_process	cell division

Functional Information from PROSITE/UniProt

site_id	PS00616
Number of Residues	15
Details	HIS_ACID_PHOSPHAT_1 Histidine acid phosphatases phosphohistidine signature. LlyAfhIyRHNyRkA

Chain	Residue	Details
AJ	LEU1083-ALA1097

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. IASVsdDhTCRIWNL

Chain	Residue	Details
CK	ILE140-LEU154
AI	VAL233-VAL247

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:23186163

Chain	Residue	Details
AJ	SER44
DJ	SER44
DJ	SER490
DJ	SER949
AJ	SER490
AJ	SER949
BJ	SER44
BJ	SER490
BJ	SER949
CJ	SER44
CJ	SER490
CJ	SER949

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:18691976, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
AJ	SER1157
BJ	SER1157
CJ	SER1157
DJ	SER1157
CG	LYS12
CD	SER11
DG	LYS12
DD	SER11

site_id	SWS_FT_FI3
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18691976

Chain	Residue	Details
AH	SER223
BC	SER1133
CC	SER15
CC	SER72
CC	SER131
CC	SER755
CC	SER1133
DC	SER15
DC	SER72
DC	SER131
DC	SER755
BH	SER223
DC	SER1133
CH	SER223
DH	SER223
CD	SER10
CD	SER57
DD	SER10
DD	SER57
BC	SER755

site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:20068231

Chain	Residue	Details
AE	SER54
BE	SER54
CE	SER54
DE	SER54

site_id	SWS_FT_FI5
Number of Residues	4
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
AE	THR120
BE	THR120
CE	THR120
DE	THR120

site_id	SWS_FT_FI6
Number of Residues	8
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
AE	SER143
AE	SER163
BE	SER143
BE	SER163
CE	SER143
CE	SER163
DE	SER143
DE	SER163

site_id	SWS_FT_FI7
Number of Residues	8
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:16964243, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
AE	SER148
AE	SER180
BE	SER148
BE	SER180
CE	SER148
CE	SER180
DE	SER148
DE	SER180

site_id	SWS_FT_FI8
Number of Residues	8
Details	MOD_RES: Phosphoserine => ECO:0000250\|UniProtKB:Q6PFD9

Chain	Residue	Details
AE	SER184
AE	SER449
BE	SER184
BE	SER449
CE	SER184
CE	SER449
DE	SER184
DE	SER449

site_id	SWS_FT_FI9
Number of Residues	4
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18669648

Chain	Residue	Details
AE	THR190
BE	THR190
CE	THR190
DE	THR190

site_id	SWS_FT_FI10
Number of Residues	4
Details	MOD_RES: Phosphothreonine => ECO:0000250\|UniProtKB:Q6PFD9

Chain	Residue	Details
AE	THR892
BE	THR892
CE	THR892
DE	THR892

site_id	SWS_FT_FI11
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648

Chain	Residue	Details
AD	SER69
BD	SER69
CD	SER69
DD	SER69

site_id	SWS_FT_FI12
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
AD	SER86
DC	SER489
DC	SER493
DC	SER501
BD	SER86
CD	SER86
DD	SER86
BC	SER493
BC	SER501
CC	SER489
CC	SER493
CC	SER501

site_id	SWS_FT_FI13
Number of Residues	4
Details	MOD_RES: N6-acetyllysine => ECO:0000250\|UniProtKB:Q8R0G9

Chain	Residue	Details
AC	LYS787
BC	LYS787
CC	LYS787
DC	LYS787

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)