7PBJ

Cryo-EM structure of the GroEL-GroES complex with ADP bound to both rings ("wide" conformation).

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
Ad	0000166	molecular_function	nucleotide binding
Ad	0000287	molecular_function	magnesium ion binding
Ad	0005515	molecular_function	protein binding
Ad	0005524	molecular_function	ATP binding
Ad	0005737	cellular_component	cytoplasm
Ad	0005829	cellular_component	cytosol
Ad	0006457	biological_process	protein folding
Ad	0009314	biological_process	response to radiation
Ad	0009408	biological_process	response to heat
Ad	0016020	cellular_component	membrane
Ad	0016853	molecular_function	isomerase activity
Ad	0016887	molecular_function	ATP hydrolysis activity
Ad	0019068	biological_process	virion assembly
Ad	0042026	biological_process	protein refolding
Ad	0042802	molecular_function	identical protein binding
Ad	0051082	molecular_function	unfolded protein binding
Ad	0140662	molecular_function	ATP-dependent protein folding chaperone
Ad	1990220	cellular_component	GroEL-GroES complex
Ae	0000166	molecular_function	nucleotide binding
Ae	0000287	molecular_function	magnesium ion binding
Ae	0005515	molecular_function	protein binding
Ae	0005524	molecular_function	ATP binding
Ae	0005737	cellular_component	cytoplasm
Ae	0005829	cellular_component	cytosol
Ae	0006457	biological_process	protein folding
Ae	0009314	biological_process	response to radiation
Ae	0009408	biological_process	response to heat
Ae	0016020	cellular_component	membrane
Ae	0016853	molecular_function	isomerase activity
Ae	0016887	molecular_function	ATP hydrolysis activity
Ae	0019068	biological_process	virion assembly
Ae	0042026	biological_process	protein refolding
Ae	0042802	molecular_function	identical protein binding
Ae	0051082	molecular_function	unfolded protein binding
Ae	0140662	molecular_function	ATP-dependent protein folding chaperone
Ae	1990220	cellular_component	GroEL-GroES complex
Af	0005515	molecular_function	protein binding
Af	0005524	molecular_function	ATP binding
Af	0005737	cellular_component	cytoplasm
Af	0005829	cellular_component	cytosol
Af	0006457	biological_process	protein folding
Af	0009408	biological_process	response to heat
Af	0019068	biological_process	virion assembly
Af	0042802	molecular_function	identical protein binding
Af	0044183	molecular_function	protein folding chaperone
Af	0046872	molecular_function	metal ion binding
Af	0051082	molecular_function	unfolded protein binding
Af	0051087	molecular_function	protein-folding chaperone binding
Af	1990220	cellular_component	GroEL-GroES complex
Ak	0000166	molecular_function	nucleotide binding
Ak	0000287	molecular_function	magnesium ion binding
Ak	0005515	molecular_function	protein binding
Ak	0005524	molecular_function	ATP binding
Ak	0005737	cellular_component	cytoplasm
Ak	0005829	cellular_component	cytosol
Ak	0006457	biological_process	protein folding
Ak	0009314	biological_process	response to radiation
Ak	0009408	biological_process	response to heat
Ak	0016020	cellular_component	membrane
Ak	0016853	molecular_function	isomerase activity
Ak	0016887	molecular_function	ATP hydrolysis activity
Ak	0019068	biological_process	virion assembly
Ak	0042026	biological_process	protein refolding
Ak	0042802	molecular_function	identical protein binding
Ak	0051082	molecular_function	unfolded protein binding
Ak	0140662	molecular_function	ATP-dependent protein folding chaperone
Ak	1990220	cellular_component	GroEL-GroES complex
Al	0000166	molecular_function	nucleotide binding
Al	0000287	molecular_function	magnesium ion binding
Al	0005515	molecular_function	protein binding
Al	0005524	molecular_function	ATP binding
Al	0005737	cellular_component	cytoplasm
Al	0005829	cellular_component	cytosol
Al	0006457	biological_process	protein folding
Al	0009314	biological_process	response to radiation
Al	0009408	biological_process	response to heat
Al	0016020	cellular_component	membrane
Al	0016853	molecular_function	isomerase activity
Al	0016887	molecular_function	ATP hydrolysis activity
Al	0019068	biological_process	virion assembly
Al	0042026	biological_process	protein refolding
Al	0042802	molecular_function	identical protein binding
Al	0051082	molecular_function	unfolded protein binding
Al	0140662	molecular_function	ATP-dependent protein folding chaperone
Al	1990220	cellular_component	GroEL-GroES complex
Am	0005515	molecular_function	protein binding
Am	0005524	molecular_function	ATP binding
Am	0005737	cellular_component	cytoplasm
Am	0005829	cellular_component	cytosol
Am	0006457	biological_process	protein folding
Am	0009408	biological_process	response to heat
Am	0019068	biological_process	virion assembly
Am	0042802	molecular_function	identical protein binding
Am	0044183	molecular_function	protein folding chaperone
Am	0046872	molecular_function	metal ion binding
Am	0051082	molecular_function	unfolded protein binding
Am	0051087	molecular_function	protein-folding chaperone binding
Am	1990220	cellular_component	GroEL-GroES complex
Ar	0000166	molecular_function	nucleotide binding
Ar	0000287	molecular_function	magnesium ion binding
Ar	0005515	molecular_function	protein binding
Ar	0005524	molecular_function	ATP binding
Ar	0005737	cellular_component	cytoplasm
Ar	0005829	cellular_component	cytosol
Ar	0006457	biological_process	protein folding
Ar	0009314	biological_process	response to radiation
Ar	0009408	biological_process	response to heat
Ar	0016020	cellular_component	membrane
Ar	0016853	molecular_function	isomerase activity
Ar	0016887	molecular_function	ATP hydrolysis activity
Ar	0019068	biological_process	virion assembly
Ar	0042026	biological_process	protein refolding
Ar	0042802	molecular_function	identical protein binding
Ar	0051082	molecular_function	unfolded protein binding
Ar	0140662	molecular_function	ATP-dependent protein folding chaperone
Ar	1990220	cellular_component	GroEL-GroES complex
As	0000166	molecular_function	nucleotide binding
As	0000287	molecular_function	magnesium ion binding
As	0005515	molecular_function	protein binding
As	0005524	molecular_function	ATP binding
As	0005737	cellular_component	cytoplasm
As	0005829	cellular_component	cytosol
As	0006457	biological_process	protein folding
As	0009314	biological_process	response to radiation
As	0009408	biological_process	response to heat
As	0016020	cellular_component	membrane
As	0016853	molecular_function	isomerase activity
As	0016887	molecular_function	ATP hydrolysis activity
As	0019068	biological_process	virion assembly
As	0042026	biological_process	protein refolding
As	0042802	molecular_function	identical protein binding
As	0051082	molecular_function	unfolded protein binding
As	0140662	molecular_function	ATP-dependent protein folding chaperone
As	1990220	cellular_component	GroEL-GroES complex
At	0005515	molecular_function	protein binding
At	0005524	molecular_function	ATP binding
At	0005737	cellular_component	cytoplasm
At	0005829	cellular_component	cytosol
At	0006457	biological_process	protein folding
At	0009408	biological_process	response to heat
At	0019068	biological_process	virion assembly
At	0042802	molecular_function	identical protein binding
At	0044183	molecular_function	protein folding chaperone
At	0046872	molecular_function	metal ion binding
At	0051082	molecular_function	unfolded protein binding
At	0051087	molecular_function	protein-folding chaperone binding
At	1990220	cellular_component	GroEL-GroES complex
Ay	0000166	molecular_function	nucleotide binding
Ay	0000287	molecular_function	magnesium ion binding
Ay	0005515	molecular_function	protein binding
Ay	0005524	molecular_function	ATP binding
Ay	0005737	cellular_component	cytoplasm
Ay	0005829	cellular_component	cytosol
Ay	0006457	biological_process	protein folding
Ay	0009314	biological_process	response to radiation
Ay	0009408	biological_process	response to heat
Ay	0016020	cellular_component	membrane
Ay	0016853	molecular_function	isomerase activity
Ay	0016887	molecular_function	ATP hydrolysis activity
Ay	0019068	biological_process	virion assembly
Ay	0042026	biological_process	protein refolding
Ay	0042802	molecular_function	identical protein binding
Ay	0051082	molecular_function	unfolded protein binding
Ay	0140662	molecular_function	ATP-dependent protein folding chaperone
Ay	1990220	cellular_component	GroEL-GroES complex
Az	0000166	molecular_function	nucleotide binding
Az	0000287	molecular_function	magnesium ion binding
Az	0005515	molecular_function	protein binding
Az	0005524	molecular_function	ATP binding
Az	0005737	cellular_component	cytoplasm
Az	0005829	cellular_component	cytosol
Az	0006457	biological_process	protein folding
Az	0009314	biological_process	response to radiation
Az	0009408	biological_process	response to heat
Az	0016020	cellular_component	membrane
Az	0016853	molecular_function	isomerase activity
Az	0016887	molecular_function	ATP hydrolysis activity
Az	0019068	biological_process	virion assembly
Az	0042026	biological_process	protein refolding
Az	0042802	molecular_function	identical protein binding
Az	0051082	molecular_function	unfolded protein binding
Az	0140662	molecular_function	ATP-dependent protein folding chaperone
Az	1990220	cellular_component	GroEL-GroES complex
Ba	0005515	molecular_function	protein binding
Ba	0005524	molecular_function	ATP binding
Ba	0005737	cellular_component	cytoplasm
Ba	0005829	cellular_component	cytosol
Ba	0006457	biological_process	protein folding
Ba	0009408	biological_process	response to heat
Ba	0019068	biological_process	virion assembly
Ba	0042802	molecular_function	identical protein binding
Ba	0044183	molecular_function	protein folding chaperone
Ba	0046872	molecular_function	metal ion binding
Ba	0051082	molecular_function	unfolded protein binding
Ba	0051087	molecular_function	protein-folding chaperone binding
Ba	1990220	cellular_component	GroEL-GroES complex
Bf	0000166	molecular_function	nucleotide binding
Bf	0000287	molecular_function	magnesium ion binding
Bf	0005515	molecular_function	protein binding
Bf	0005524	molecular_function	ATP binding
Bf	0005737	cellular_component	cytoplasm
Bf	0005829	cellular_component	cytosol
Bf	0006457	biological_process	protein folding
Bf	0009314	biological_process	response to radiation
Bf	0009408	biological_process	response to heat
Bf	0016020	cellular_component	membrane
Bf	0016853	molecular_function	isomerase activity
Bf	0016887	molecular_function	ATP hydrolysis activity
Bf	0019068	biological_process	virion assembly
Bf	0042026	biological_process	protein refolding
Bf	0042802	molecular_function	identical protein binding
Bf	0051082	molecular_function	unfolded protein binding
Bf	0140662	molecular_function	ATP-dependent protein folding chaperone
Bf	1990220	cellular_component	GroEL-GroES complex
Bg	0000166	molecular_function	nucleotide binding
Bg	0000287	molecular_function	magnesium ion binding
Bg	0005515	molecular_function	protein binding
Bg	0005524	molecular_function	ATP binding
Bg	0005737	cellular_component	cytoplasm
Bg	0005829	cellular_component	cytosol
Bg	0006457	biological_process	protein folding
Bg	0009314	biological_process	response to radiation
Bg	0009408	biological_process	response to heat
Bg	0016020	cellular_component	membrane
Bg	0016853	molecular_function	isomerase activity
Bg	0016887	molecular_function	ATP hydrolysis activity
Bg	0019068	biological_process	virion assembly
Bg	0042026	biological_process	protein refolding
Bg	0042802	molecular_function	identical protein binding
Bg	0051082	molecular_function	unfolded protein binding
Bg	0140662	molecular_function	ATP-dependent protein folding chaperone
Bg	1990220	cellular_component	GroEL-GroES complex
Bh	0005515	molecular_function	protein binding
Bh	0005524	molecular_function	ATP binding
Bh	0005737	cellular_component	cytoplasm
Bh	0005829	cellular_component	cytosol
Bh	0006457	biological_process	protein folding
Bh	0009408	biological_process	response to heat
Bh	0019068	biological_process	virion assembly
Bh	0042802	molecular_function	identical protein binding
Bh	0044183	molecular_function	protein folding chaperone
Bh	0046872	molecular_function	metal ion binding
Bh	0051082	molecular_function	unfolded protein binding
Bh	0051087	molecular_function	protein-folding chaperone binding
Bh	1990220	cellular_component	GroEL-GroES complex
Bm	0000166	molecular_function	nucleotide binding
Bm	0000287	molecular_function	magnesium ion binding
Bm	0005515	molecular_function	protein binding
Bm	0005524	molecular_function	ATP binding
Bm	0005737	cellular_component	cytoplasm
Bm	0005829	cellular_component	cytosol
Bm	0006457	biological_process	protein folding
Bm	0009314	biological_process	response to radiation
Bm	0009408	biological_process	response to heat
Bm	0016020	cellular_component	membrane
Bm	0016853	molecular_function	isomerase activity
Bm	0016887	molecular_function	ATP hydrolysis activity
Bm	0019068	biological_process	virion assembly
Bm	0042026	biological_process	protein refolding
Bm	0042802	molecular_function	identical protein binding
Bm	0051082	molecular_function	unfolded protein binding
Bm	0140662	molecular_function	ATP-dependent protein folding chaperone
Bm	1990220	cellular_component	GroEL-GroES complex
Bn	0000166	molecular_function	nucleotide binding
Bn	0000287	molecular_function	magnesium ion binding
Bn	0005515	molecular_function	protein binding
Bn	0005524	molecular_function	ATP binding
Bn	0005737	cellular_component	cytoplasm
Bn	0005829	cellular_component	cytosol
Bn	0006457	biological_process	protein folding
Bn	0009314	biological_process	response to radiation
Bn	0009408	biological_process	response to heat
Bn	0016020	cellular_component	membrane
Bn	0016853	molecular_function	isomerase activity
Bn	0016887	molecular_function	ATP hydrolysis activity
Bn	0019068	biological_process	virion assembly
Bn	0042026	biological_process	protein refolding
Bn	0042802	molecular_function	identical protein binding
Bn	0051082	molecular_function	unfolded protein binding
Bn	0140662	molecular_function	ATP-dependent protein folding chaperone
Bn	1990220	cellular_component	GroEL-GroES complex
Bo	0005515	molecular_function	protein binding
Bo	0005524	molecular_function	ATP binding
Bo	0005737	cellular_component	cytoplasm
Bo	0005829	cellular_component	cytosol
Bo	0006457	biological_process	protein folding
Bo	0009408	biological_process	response to heat
Bo	0019068	biological_process	virion assembly
Bo	0042802	molecular_function	identical protein binding
Bo	0044183	molecular_function	protein folding chaperone
Bo	0046872	molecular_function	metal ion binding
Bo	0051082	molecular_function	unfolded protein binding
Bo	0051087	molecular_function	protein-folding chaperone binding
Bo	1990220	cellular_component	GroEL-GroES complex
Bt	0000166	molecular_function	nucleotide binding
Bt	0000287	molecular_function	magnesium ion binding
Bt	0005515	molecular_function	protein binding
Bt	0005524	molecular_function	ATP binding
Bt	0005737	cellular_component	cytoplasm
Bt	0005829	cellular_component	cytosol
Bt	0006457	biological_process	protein folding
Bt	0009314	biological_process	response to radiation
Bt	0009408	biological_process	response to heat
Bt	0016020	cellular_component	membrane
Bt	0016853	molecular_function	isomerase activity
Bt	0016887	molecular_function	ATP hydrolysis activity
Bt	0019068	biological_process	virion assembly
Bt	0042026	biological_process	protein refolding
Bt	0042802	molecular_function	identical protein binding
Bt	0051082	molecular_function	unfolded protein binding
Bt	0140662	molecular_function	ATP-dependent protein folding chaperone
Bt	1990220	cellular_component	GroEL-GroES complex
Bu	0000166	molecular_function	nucleotide binding
Bu	0000287	molecular_function	magnesium ion binding
Bu	0005515	molecular_function	protein binding
Bu	0005524	molecular_function	ATP binding
Bu	0005737	cellular_component	cytoplasm
Bu	0005829	cellular_component	cytosol
Bu	0006457	biological_process	protein folding
Bu	0009314	biological_process	response to radiation
Bu	0009408	biological_process	response to heat
Bu	0016020	cellular_component	membrane
Bu	0016853	molecular_function	isomerase activity
Bu	0016887	molecular_function	ATP hydrolysis activity
Bu	0019068	biological_process	virion assembly
Bu	0042026	biological_process	protein refolding
Bu	0042802	molecular_function	identical protein binding
Bu	0051082	molecular_function	unfolded protein binding
Bu	0140662	molecular_function	ATP-dependent protein folding chaperone
Bu	1990220	cellular_component	GroEL-GroES complex
Bv	0005515	molecular_function	protein binding
Bv	0005524	molecular_function	ATP binding
Bv	0005737	cellular_component	cytoplasm
Bv	0005829	cellular_component	cytosol
Bv	0006457	biological_process	protein folding
Bv	0009408	biological_process	response to heat
Bv	0019068	biological_process	virion assembly
Bv	0042802	molecular_function	identical protein binding
Bv	0044183	molecular_function	protein folding chaperone
Bv	0046872	molecular_function	metal ion binding
Bv	0051082	molecular_function	unfolded protein binding
Bv	0051087	molecular_function	protein-folding chaperone binding
Bv	1990220	cellular_component	GroEL-GroES complex

Functional Information from PROSITE/UniProt

site_id	PS00296
Number of Residues	12
Details	CHAPERONINS_CPN60 Chaperonins cpn60 signature. AAVEEGVVaGGG

Chain	Residue	Details
Ad	ALA405-GLY416

---

site_id	PS00681
Number of Residues	25
Details	CHAPERONINS_CPN10 Chaperonins cpn10 signature. IrPLhDRVIVKrkevetksaGgIVL

Chain	Residue	Details
Af	ILE3-LEU27

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	154
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00600","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"25174333","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14517228","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9285585","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1AON","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1PCQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1PF9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3WVL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00600","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"25174333","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14517228","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9285585","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1AON","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1PF9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3WVL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	77
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"PubMed","id":"21151122","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	14
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"PubMed","id":"21151122","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---