7P91
TmHydABC- T. maritima bifurcating hydrogenase with bridge domain closed
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| a | 0005737 | cellular_component | cytoplasm |
| a | 0008137 | molecular_function | NADH dehydrogenase (ubiquinone) activity |
| a | 0016020 | cellular_component | membrane |
| a | 0016491 | molecular_function | oxidoreductase activity |
| a | 0042773 | biological_process | ATP synthesis coupled electron transport |
| a | 0046872 | molecular_function | metal ion binding |
| a | 0051536 | molecular_function | iron-sulfur cluster binding |
| a | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| a | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| a | 1902600 | biological_process | proton transmembrane transport |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008137 | molecular_function | NADH dehydrogenase (ubiquinone) activity |
| A | 0016020 | cellular_component | membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0042773 | biological_process | ATP synthesis coupled electron transport |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| A | 1902600 | biological_process | proton transmembrane transport |
| b | 0005737 | cellular_component | cytoplasm |
| b | 0008137 | molecular_function | NADH dehydrogenase (ubiquinone) activity |
| b | 0010181 | molecular_function | FMN binding |
| b | 0016491 | molecular_function | oxidoreductase activity |
| b | 0046872 | molecular_function | metal ion binding |
| b | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| b | 1902600 | biological_process | proton transmembrane transport |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008137 | molecular_function | NADH dehydrogenase (ubiquinone) activity |
| B | 0010181 | molecular_function | FMN binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| B | 1902600 | biological_process | proton transmembrane transport |
| c | 0005737 | cellular_component | cytoplasm |
| c | 0016491 | molecular_function | oxidoreductase activity |
| c | 0046872 | molecular_function | metal ion binding |
| c | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
Functional Information from PROSITE/UniProt
| site_id | PS00198 |
| Number of Residues | 12 |
| Details | 4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CkGCGlCArSCP |
| Chain | Residue | Details |
| b | CYS578-PRO589 | |
| b | CYS608-PRO619 | |
| a | CYS143-GLU154 | |
| a | CYS186-PRO197 |
| site_id | PS00641 |
| Number of Residues | 18 |
| Details | COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PnlCYlseasiyGaCRmC |
| Chain | Residue | Details |
| a | PRO31-CYS48 |
| site_id | PS00645 |
| Number of Residues | 12 |
| Details | COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGkCvPCReG |
| Chain | Residue | Details |
| b | GLU483-GLY494 |
| site_id | PS01099 |
| Number of Residues | 19 |
| Details | COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DlmFSldqvgCLGaCalAP |
| Chain | Residue | Details |
| c | ASP109-PRO127 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q56221 |
| Chain | Residue | Details |
| c | ILE75 | |
| b | CYS531 | |
| B | GLY198 | |
| B | LYS207 | |
| B | ASN224 | |
| B | ASP229 | |
| B | PHE312 | |
| B | ILE350 | |
| B | CYS485 | |
| B | CYS488 | |
| B | CYS491 | |
| c | GLY80 | |
| B | CYS531 | |
| c | GLN116 | |
| c | LEU120 | |
| C | ILE75 | |
| C | GLY80 | |
| C | GLN116 | |
| C | LEU120 | |
| b | CYS491 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00711 |
| Chain | Residue | Details |
| b | CYS578 | |
| B | CYS581 | |
| B | CYS584 | |
| B | CYS588 | |
| B | CYS608 | |
| B | CYS611 | |
| B | CYS614 | |
| B | CYS618 | |
| b | CYS581 | |
| b | CYS584 | |
| b | CYS588 | |
| b | CYS608 | |
| b | CYS611 | |
| b | CYS614 | |
| b | CYS618 | |
| B | CYS578 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00711 |
| Chain | Residue | Details |
| a | CYS143 | |
| A | CYS146 | |
| A | CYS149 | |
| A | CYS153 | |
| A | CYS186 | |
| A | CYS189 | |
| A | CYS192 | |
| A | CYS196 | |
| a | CYS146 | |
| a | CYS149 | |
| a | CYS153 | |
| a | CYS186 | |
| a | CYS189 | |
| a | CYS192 | |
| a | CYS196 | |
| A | CYS143 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q56221 |
| Chain | Residue | Details |
| a | CYS575 | |
| a | CYS580 | |
| a | CYS612 | |
| a | CYS616 | |
| A | CYS575 | |
| A | CYS580 | |
| A | CYS612 | |
| A | CYS616 |
