7P8N

TmHydABC- T. maritima hydrogenase with bridge closed

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0005737	cellular_component	cytoplasm
a	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
a	0016020	cellular_component	membrane
a	0016491	molecular_function	oxidoreductase activity
a	0042773	biological_process	ATP synthesis coupled electron transport
a	0046872	molecular_function	metal ion binding
a	0051536	molecular_function	iron-sulfur cluster binding
a	0051537	molecular_function	2 iron, 2 sulfur cluster binding
a	0051539	molecular_function	4 iron, 4 sulfur cluster binding
a	0102220	molecular_function	hydrogenase activity (NAD+, ferredoxin)
a	1902600	biological_process	proton transmembrane transport
A	0005737	cellular_component	cytoplasm
A	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0042773	biological_process	ATP synthesis coupled electron transport
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A	0102220	molecular_function	hydrogenase activity (NAD+, ferredoxin)
A	1902600	biological_process	proton transmembrane transport
b	0005737	cellular_component	cytoplasm
b	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
b	0010181	molecular_function	FMN binding
b	0016491	molecular_function	oxidoreductase activity
b	0046872	molecular_function	metal ion binding
b	0051536	molecular_function	iron-sulfur cluster binding
b	0051539	molecular_function	4 iron, 4 sulfur cluster binding
b	0102220	molecular_function	hydrogenase activity (NAD+, ferredoxin)
b	1902600	biological_process	proton transmembrane transport
B	0005737	cellular_component	cytoplasm
B	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
B	0010181	molecular_function	FMN binding
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
B	0051536	molecular_function	iron-sulfur cluster binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
B	0102220	molecular_function	hydrogenase activity (NAD+, ferredoxin)
B	1902600	biological_process	proton transmembrane transport
c	0005737	cellular_component	cytoplasm
c	0016491	molecular_function	oxidoreductase activity
c	0046872	molecular_function	metal ion binding
c	0051536	molecular_function	iron-sulfur cluster binding
c	0051537	molecular_function	2 iron, 2 sulfur cluster binding
c	0102220	molecular_function	hydrogenase activity (NAD+, ferredoxin)
C	0005737	cellular_component	cytoplasm
C	0016491	molecular_function	oxidoreductase activity
C	0046872	molecular_function	metal ion binding
C	0051536	molecular_function	iron-sulfur cluster binding
C	0051537	molecular_function	2 iron, 2 sulfur cluster binding
C	0102220	molecular_function	hydrogenase activity (NAD+, ferredoxin)

Functional Information from PROSITE/UniProt

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiLCGdCVrVCE

Chain	Residue	Details
a	CYS143-GLU154
a	CYS186-PRO197
b	CYS578-PRO589
b	CYS608-PRO619

---

site_id	PS00641
Number of Residues	18
Details	COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PnlCYlseasiyGaCRmC

Chain	Residue	Details
a	PRO31-CYS48

---

site_id	PS00645
Number of Residues	12
Details	COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGkCvPCReG

Chain	Residue	Details
b	GLU483-GLY494

---

site_id	PS01099
Number of Residues	19
Details	COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DlmFSldqvgCLGaCalAP

Chain	Residue	Details
c	ASP109-PRO127

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	150
Details	Domain: {"description":"2Fe-2S ferredoxin-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00465","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	78
Details	Domain: {"description":"4Fe-4S His(Cys)3-ligated-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU01184","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	91
Details	Domain: {"description":"4Fe-4S ferredoxin-type 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	56
Details	Domain: {"description":"4Fe-4S ferredoxin-type 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00465","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P29166","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q56221","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	40
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q56222","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---