Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7P5H

TmHydABC- D2 map

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0042773	biological_process	ATP synthesis coupled electron transport
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A	1902600	biological_process	proton transmembrane transport
B	0005737	cellular_component	cytoplasm
B	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
B	0010181	molecular_function	FMN binding
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
B	1902600	biological_process	proton transmembrane transport
C	0005737	cellular_component	cytoplasm
C	0016491	molecular_function	oxidoreductase activity
C	0046872	molecular_function	metal ion binding
C	0051537	molecular_function	2 iron, 2 sulfur cluster binding
D	0005737	cellular_component	cytoplasm
D	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
D	0016020	cellular_component	membrane
D	0016491	molecular_function	oxidoreductase activity
D	0042773	biological_process	ATP synthesis coupled electron transport
D	0046872	molecular_function	metal ion binding
D	0051536	molecular_function	iron-sulfur cluster binding
D	0051537	molecular_function	2 iron, 2 sulfur cluster binding
D	0051539	molecular_function	4 iron, 4 sulfur cluster binding
D	1902600	biological_process	proton transmembrane transport
E	0005737	cellular_component	cytoplasm
E	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
E	0010181	molecular_function	FMN binding
E	0016491	molecular_function	oxidoreductase activity
E	0046872	molecular_function	metal ion binding
E	0051539	molecular_function	4 iron, 4 sulfur cluster binding
E	1902600	biological_process	proton transmembrane transport
F	0005737	cellular_component	cytoplasm
F	0016491	molecular_function	oxidoreductase activity
F	0046872	molecular_function	metal ion binding
F	0051537	molecular_function	2 iron, 2 sulfur cluster binding
a	0005737	cellular_component	cytoplasm
a	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
a	0016020	cellular_component	membrane
a	0016491	molecular_function	oxidoreductase activity
a	0042773	biological_process	ATP synthesis coupled electron transport
a	0046872	molecular_function	metal ion binding
a	0051536	molecular_function	iron-sulfur cluster binding
a	0051537	molecular_function	2 iron, 2 sulfur cluster binding
a	0051539	molecular_function	4 iron, 4 sulfur cluster binding
a	1902600	biological_process	proton transmembrane transport
b	0005737	cellular_component	cytoplasm
b	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
b	0010181	molecular_function	FMN binding
b	0016491	molecular_function	oxidoreductase activity
b	0046872	molecular_function	metal ion binding
b	0051539	molecular_function	4 iron, 4 sulfur cluster binding
b	1902600	biological_process	proton transmembrane transport
c	0005737	cellular_component	cytoplasm
c	0016491	molecular_function	oxidoreductase activity
c	0046872	molecular_function	metal ion binding
c	0051537	molecular_function	2 iron, 2 sulfur cluster binding
d	0005737	cellular_component	cytoplasm
d	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
d	0016020	cellular_component	membrane
d	0016491	molecular_function	oxidoreductase activity
d	0042773	biological_process	ATP synthesis coupled electron transport
d	0046872	molecular_function	metal ion binding
d	0051536	molecular_function	iron-sulfur cluster binding
d	0051537	molecular_function	2 iron, 2 sulfur cluster binding
d	0051539	molecular_function	4 iron, 4 sulfur cluster binding
d	1902600	biological_process	proton transmembrane transport
e	0005737	cellular_component	cytoplasm
e	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
e	0010181	molecular_function	FMN binding
e	0016491	molecular_function	oxidoreductase activity
e	0046872	molecular_function	metal ion binding
e	0051539	molecular_function	4 iron, 4 sulfur cluster binding
e	1902600	biological_process	proton transmembrane transport
f	0005737	cellular_component	cytoplasm
f	0016491	molecular_function	oxidoreductase activity
f	0046872	molecular_function	metal ion binding
f	0051537	molecular_function	2 iron, 2 sulfur cluster binding

Functional Information from PROSITE/UniProt

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CkGCGlCArSCP

Chain	Residue	Details
B	CYS578-PRO589
B	CYS608-PRO619
A	CYS143-GLU154
A	CYS186-PRO197

site_id	PS00641
Number of Residues	18
Details	COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PnlCYlseasiyGaCRmC

Chain	Residue	Details
A	PRO31-CYS48

site_id	PS00645
Number of Residues	12
Details	COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGkCvPCReG

Chain	Residue	Details
B	GLU483-GLY494

site_id	PS01099
Number of Residues	19
Details	COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DlmFSldqvgCLGaCalAP

Chain	Residue	Details
C	ASP109-PRO127

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:Q56221

Chain	Residue	Details
C	ILE75
c	GLY80
c	GLN116
c	LEU120
f	ILE75
f	GLY80
f	GLN116
f	LEU120
E	CYS485
E	CYS488
E	CYS491
C	GLY80
E	CYS531
b	GLY198
b	LYS207
b	ASN224
b	ASP229
b	PHE312
b	ILE350
b	CYS485
b	CYS488
b	CYS491
C	GLN116
b	CYS531
e	GLY198
e	LYS207
e	ASN224
e	ASP229
e	PHE312
e	ILE350
e	CYS485
e	CYS488
e	CYS491
C	LEU120
e	CYS531
F	ILE75
F	GLY80
F	GLN116
F	LEU120
c	ILE75

site_id	SWS_FT_FI2
Number of Residues	32
Details	BINDING: BINDING => ECO:0000255\|PROSITE-ProRule:PRU00711

Chain	Residue	Details
B	CYS578
E	CYS581
E	CYS584
E	CYS588
E	CYS608
E	CYS611
E	CYS614
E	CYS618
b	CYS578
b	CYS581
b	CYS584
B	CYS581
b	CYS588
b	CYS608
b	CYS611
b	CYS614
b	CYS618
e	CYS578
e	CYS581
e	CYS584
e	CYS588
e	CYS608
B	CYS584
e	CYS611
e	CYS614
e	CYS618
B	CYS588
B	CYS608
B	CYS611
B	CYS614
B	CYS618
E	CYS578

site_id	SWS_FT_FI3
Number of Residues	32
Details	BINDING: BINDING => ECO:0000255\|PROSITE-ProRule:PRU00711

Chain	Residue	Details
A	CYS143
D	CYS146
D	CYS149
D	CYS153
D	CYS186
D	CYS189
D	CYS192
D	CYS196
a	CYS143
a	CYS146
a	CYS149
A	CYS146
a	CYS153
a	CYS186
a	CYS189
a	CYS192
a	CYS196
d	CYS143
d	CYS146
d	CYS149
d	CYS153
d	CYS186
A	CYS149
d	CYS189
d	CYS192
d	CYS196
A	CYS153
A	CYS186
A	CYS189
A	CYS192
A	CYS196
D	CYS143

site_id	SWS_FT_FI4
Number of Residues	16
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:Q56221

Chain	Residue	Details
A	CYS575
a	CYS580
a	CYS612
a	CYS616
d	CYS575
d	CYS580
d	CYS612
d	CYS616
A	CYS580
A	CYS612
A	CYS616
D	CYS575
D	CYS580
D	CYS612
D	CYS616
a	CYS575

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)