7P4L
Crystal structure of the trimeric ectodomain of archaeal Fusexin1 (Fsx1)
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 237 |
| Details | Region: {"description":"Domain II N-terminus","evidences":[{"source":"PubMed","id":"35794124","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 15 |
| Details | Region: {"description":"Fusion loop, required for fusogenic activity, not required for membrane surface localization","evidences":[{"source":"PubMed","id":"35794124","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 159 |
| Details | Region: {"description":"Domain I central section","evidences":[{"source":"PubMed","id":"35794124","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 273 |
| Details | Region: {"description":"Domain II C-terminus","evidences":[{"source":"PubMed","id":"35794124","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 93 |
| Details | Region: {"description":"Domain I C-terminus","evidences":[{"source":"PubMed","id":"35794124","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 318 |
| Details | Region: {"description":"Domain III","evidences":[{"source":"PubMed","id":"35794124","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 72 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"35794124","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7P4L","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 106 |
| Details | Region: {"description":"Domain IV, required for fusogenic activity","evidences":[{"source":"PubMed","id":"35794124","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
