7P2T

Tetartohedrally twinned crystal structure of Schistosoma mansoni HDAC8 in complex with a tricyclic thieno[3,2-b]indole capped hydroxamate-based inhibitor, bromine derivative

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004407	molecular_function	histone deacetylase activity
A	0005634	cellular_component	nucleus
A	0006325	biological_process	chromatin organization
A	0031507	biological_process	heterochromatin formation
A	0046872	molecular_function	metal ion binding
B	0004407	molecular_function	histone deacetylase activity
B	0005634	cellular_component	nucleus
B	0006325	biological_process	chromatin organization
B	0031507	biological_process	heterochromatin formation
B	0046872	molecular_function	metal ion binding
C	0004407	molecular_function	histone deacetylase activity
C	0005634	cellular_component	nucleus
C	0006325	biological_process	chromatin organization
C	0031507	biological_process	heterochromatin formation
C	0046872	molecular_function	metal ion binding
D	0004407	molecular_function	histone deacetylase activity
D	0005634	cellular_component	nucleus
D	0006325	biological_process	chromatin organization
D	0031507	biological_process	heterochromatin formation
D	0046872	molecular_function	metal ion binding