7P16

Structure of caspase-3 cleaved rXKR9 in complex with a sybody at 4.3A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0016020	cellular_component	membrane
A	0017128	molecular_function	phospholipid scramblase activity
A	0070782	biological_process	phosphatidylserine exposure on apoptotic cell surface

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	39
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"34263724","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7P14","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7P16","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"34263724","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7P14","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7P16","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	19
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"34263724","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7P14","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7P16","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	21
Details	Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"34263724","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7P14","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7P16","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	13
Details	Intramembrane: {"description":"Helical; Name=IH1","evidences":[{"source":"PubMed","id":"34263724","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7P14","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7P16","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	24
Details	Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"34263724","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7P14","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7P16","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	22
Details	Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"34263724","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7P14","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7P16","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	26
Details	Transmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"34263724","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7P14","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7P16","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	19
Details	Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"34263724","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7P14","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7P16","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	15
Details	Intramembrane: {"description":"Helical; Name=IH2","evidences":[{"source":"PubMed","id":"34263724","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7P14","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7P16","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	22
Details	Transmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"34263724","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7P14","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7P16","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	22
Details	Transmembrane: {"description":"Helical; Name=8","evidences":[{"source":"PubMed","id":"34263724","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7P14","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7P16","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"34263724","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7P14","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---