7P0W
Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing thymine opposite to lesion)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000702 | molecular_function | oxidized base lesion DNA N-glycosylase activity |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003906 | molecular_function | DNA-(apurinic or apyrimidinic site) endonuclease activity |
| A | 0006281 | biological_process | DNA repair |
| A | 0006284 | biological_process | base-excision repair |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
| A | 0016829 | molecular_function | lyase activity |
| A | 0140078 | molecular_function | class I DNA-(apurinic or apyrimidinic site) endonuclease activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Schiff-base intermediate with DNA => ECO:0000255|HAMAP-Rule:MF_01168 |
| Chain | Residue | Details |
| A | LYS142 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_01168 |
| Chain | Residue | Details |
| A | ASP174 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01168 |
| Chain | Residue | Details |
| A | GLN24 | |
| A | SER51 | |
| A | TRP62 | |
| A | PHE146 | |
| A | PRO172 | |
| A | ASP208 | |
| A | TRP212 |
