7OVS

Heterodimeric murine tRNA-guanine transglycosylase in the presence of Anderson-Evans type (TEW) and Strandberg type polyoxometalate (POM)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005741	cellular_component	mitochondrial outer membrane
A	0006400	biological_process	tRNA modification
A	0008033	biological_process	tRNA processing
A	0008270	molecular_function	zinc ion binding
A	0008479	molecular_function	tRNA-guanosine(34) queuine transglycosylase activity
A	0016763	molecular_function	pentosyltransferase activity
A	0032473	cellular_component	cytoplasmic side of mitochondrial outer membrane
A	0032991	cellular_component	protein-containing complex
A	0042803	molecular_function	protein homodimerization activity
A	0046872	molecular_function	metal ion binding
A	0046982	molecular_function	protein heterodimerization activity
A	0101030	biological_process	tRNA-guanine transglycosylation
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005741	cellular_component	mitochondrial outer membrane
C	0006400	biological_process	tRNA modification
C	0008033	biological_process	tRNA processing
C	0008479	molecular_function	tRNA-guanosine(34) queuine transglycosylase activity
C	0016757	molecular_function	glycosyltransferase activity
C	0016763	molecular_function	pentosyltransferase activity
C	0032473	cellular_component	cytoplasmic side of mitochondrial outer membrane
C	0032991	cellular_component	protein-containing complex
C	0042803	molecular_function	protein homodimerization activity
C	0046872	molecular_function	metal ion binding
C	0046982	molecular_function	protein heterodimerization activity
C	0101030	biological_process	tRNA-guanine transglycosylation
C	0120507	cellular_component	tRNA-guanine transglycosylase complex
C	1990234	cellular_component	transferase complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_03218

Chain	Residue	Details
C	ASP105
A	CYS353
A	CYS356
A	HIS382

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_03218

Chain	Residue	Details
C	ASP279

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03218

Chain	Residue	Details
C	ASP105

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site_id	SWS_FT_FI4
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03218, ECO:0000269|PubMed:35815944, ECO:0007744|PDB:7OVO, ECO:0007744|PDB:7OWZ

Chain	Residue	Details
C	ASP159
C	GLN202
C	GLY229

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site_id	SWS_FT_FI5
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03218, ECO:0000269|PubMed:35815944, ECO:0007744|PDB:6H62, ECO:0007744|PDB:7B2I, ECO:0007744|PDB:7OV9, ECO:0007744|PDB:7OVO, ECO:0007744|PDB:7OVS, ECO:0007744|PDB:7OWZ

Chain	Residue	Details
C	CYS317
C	CYS319
C	CYS322
C	HIS348

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site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q9BXR0

Chain	Residue	Details
C	SER139

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