Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7OV1

Structure of Human Serum Albumin in complex with Myristic Acid

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005615	cellular_component	extracellular space
B	0005615	cellular_component	extracellular space

Functional Information from PROSITE/UniProt

site_id	PS00212
Number of Residues	25
Details	ALBUMIN_1 Albumin domain signature. YkaafteCCqaAdkaaCLlpkldeL

Chain	Residue	Details
A	TYR161-LEU185
A	TYR353-PHE377
A	PHE551-LEU575

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:P02770

Chain	Residue	Details
A	HIS3
B	HIS3

site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:P02769

Chain	Residue	Details
A	GLU6
B	GLU6
B	ASP13
B	GLU244
B	GLU252
B	ASP255
B	ASP259
A	ASP13
A	GLU244
A	GLU252
A	ASP255
A	ASP259

site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269\|PubMed:28567254, ECO:0007744\|PDB:5IJF

Chain	Residue	Details
A	HIS67
A	HIS247
A	ASP249
B	HIS67
B	HIS247
B	ASP249

site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269\|PubMed:656055

Chain	Residue	Details
A	LYS240
B	LYS240

site_id	SWS_FT_FI5
Number of Residues	74
Details	SITE: Not glycated => ECO:0000269\|PubMed:15047055

Chain	Residue	Details
A	LYS41
A	LYS64
A	LYS73
A	LYS93
A	LYS106
A	LYS136
A	LYS159
A	LYS174
A	LYS181
A	LYS190
A	LYS195
A	LYS205
A	LYS212
A	LYS240
A	LYS262
A	LYS274
A	LYS286
A	LYS359
A	LYS372
A	LYS389
A	LYS402
A	LYS414
A	LYS432
A	LYS436
A	LYS466
A	LYS475
A	LYS500
A	LYS519
A	LYS524
A	LYS538
A	LYS541
A	LYS557
A	LYS560
A	LYS564
A	LYS574
B	LYS4
B	LYS20
B	LYS41
B	LYS64
B	LYS73
B	LYS93
B	LYS106
B	LYS136
B	LYS159
B	LYS174
B	LYS181
B	LYS190
B	LYS195
B	LYS205
B	LYS212
B	LYS240
B	LYS262
B	LYS274
B	LYS286
B	LYS359
B	LYS372
B	LYS389
B	LYS402
B	LYS414
B	LYS432
B	LYS436
B	LYS466
B	LYS475
B	LYS500
B	LYS519
B	LYS524
B	LYS538
B	LYS541
B	LYS557
B	LYS560
B	LYS564
B	LYS574
A	LYS4
A	LYS20

site_id	SWS_FT_FI6
Number of Residues	2
Details	SITE: Aspirin-acetylated lysine

Chain	Residue	Details
A	LYS199
B	LYS199

site_id	SWS_FT_FI7
Number of Residues	2
Details	MOD_RES: Phosphoserine; by FAM20C => ECO:0000269\|PubMed:26091039

Chain	Residue	Details
A	SER5
B	SER5

site_id	SWS_FT_FI8
Number of Residues	2
Details	MOD_RES: Phosphoserine; by FAM20C => ECO:0000269\|PubMed:26091039, ECO:0007744\|PubMed:18318008, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
A	SER58
B	SER58

site_id	SWS_FT_FI9
Number of Residues	2
Details	MOD_RES: Phosphoserine; by FAM20C => ECO:0000269\|PubMed:26091039, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
A	SER65
B	SER65

site_id	SWS_FT_FI10
Number of Residues	2
Details	MOD_RES: Phosphothreonine; by FAM20C => ECO:0000269\|PubMed:26091039

Chain	Residue	Details
A	THR83
B	THR83

site_id	SWS_FT_FI11
Number of Residues	8
Details	MOD_RES: N6-succinyllysine => ECO:0000250\|UniProtKB:P07724

Chain	Residue	Details
A	LYS519
A	LYS564
B	LYS205
B	LYS436
B	LYS519
B	LYS564
A	LYS205
A	LYS436

site_id	SWS_FT_FI12
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250\|UniProtKB:P07724

Chain	Residue	Details
A	SER273
B	SER273

site_id	SWS_FT_FI13
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:19690332

Chain	Residue	Details
A	SER419
B	SER419

site_id	SWS_FT_FI14
Number of Residues	4
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:19690332

Chain	Residue	Details
A	THR420
A	THR422
B	THR420
B	THR422

site_id	SWS_FT_FI15
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:24275569

Chain	Residue	Details
A	SER489
B	SER489

site_id	SWS_FT_FI16
Number of Residues	2
Details	MOD_RES: N6-methyllysine; alternate => ECO:0007744\|PubMed:24129315

Chain	Residue	Details
A	LYS534
B	LYS534

site_id	SWS_FT_FI17
Number of Residues	8
Details	CARBOHYD: N-linked (Glc) (glycation) lysine => ECO:0000269\|PubMed:3759977

Chain	Residue	Details
B	LYS12
B	LYS281
B	LYS317
B	LYS439
A	LYS12
A	LYS281
A	LYS317
A	LYS439

site_id	SWS_FT_FI18
Number of Residues	26
Details	CARBOHYD: N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269\|PubMed:15047055

Chain	Residue	Details
A	LYS162
A	LYS225
A	LYS276
A	LYS313
A	LYS323
A	LYS378
A	LYS413
A	LYS444
A	LYS536
A	LYS545
A	LYS573
B	LYS51
B	LYS137
B	LYS162
B	LYS225
B	LYS276
B	LYS313
B	LYS323
B	LYS378
B	LYS413
B	LYS444
B	LYS536
B	LYS545
B	LYS573
A	LYS51
A	LYS137

site_id	SWS_FT_FI19
Number of Residues	2
Details	CARBOHYD: N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269\|PubMed:3759977, ECO:0000269\|PubMed:6853480

Chain	Residue	Details
A	LYS199
B	LYS199

site_id	SWS_FT_FI20
Number of Residues	4
Details	CARBOHYD: N-linked (Glc) (glycation) lysine => ECO:0000269\|PubMed:15047055, ECO:0000269\|PubMed:3759977

Chain	Residue	Details
A	LYS233
A	LYS351
B	LYS233
B	LYS351

site_id	SWS_FT_FI21
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; in variant Redhill

Chain	Residue	Details
A	ASN318
B	ASN318

site_id	SWS_FT_FI22
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; in variant Casebrook

Chain	Residue	Details
A	ASP494
B	ASP494

site_id	SWS_FT_FI23
Number of Residues	2
Details	CARBOHYD: N-linked (Glc) (glycation) lysine => ECO:0000269\|PubMed:15047055, ECO:0000269\|PubMed:3759977, ECO:0000269\|PubMed:6706980, ECO:0000269\|PubMed:6853480

Chain	Residue	Details
A	LYS525
B	LYS525

site_id	SWS_FT_FI24
Number of Residues	2
Details	CARBOHYD: N-linked (Glc) (glycation) lysine; alternate => ECO:0000269\|PubMed:3759977

Chain	Residue	Details
A	LYS534
B	LYS534

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)