7OSZ
Human Prolyl-tRNA Synthetase in Complex with L-proline and Compound 4d
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004827 | molecular_function | proline-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006433 | biological_process | prolyl-tRNA aminoacylation |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004827 | molecular_function | proline-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006433 | biological_process | prolyl-tRNA aminoacylation |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24100331","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4K87","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23263184","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24100331","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37212275","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4HVC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4K87","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7Y1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7Y1W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7Y28","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7Y3S","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"37212275","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7Y1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7Y1W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7Y28","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7Y3S","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23263184","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24100331","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29273753","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37212275","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4HVC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4K86","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4K87","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5V58","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7Y1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7Y1W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7Y28","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7Y3S","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23263184","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24100331","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37212275","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4HVC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4K86","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4K87","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4K88","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7Y1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7Y1W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7Y28","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7Y3S","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23263184","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24100331","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29273753","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37212275","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4HVC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4K86","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4K87","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4K88","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5V58","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7Y1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7Y1W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7Y28","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7Y3S","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"PubMed","id":"24129315","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
