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7ORZ

Crystal structure of UDP-N-acetylenolpyruvoylglucosamine reductase (MurB) from Pseudomonas aeruginosa in complex with FAD and a pyrazole derivative (fragment 18)

Functional Information from GO Data
ChainGOidnamespacecontents
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0008360biological_processregulation of cell shape
A0008762molecular_functionUDP-N-acetylmuramate dehydrogenase activity
A0009252biological_processpeptidoglycan biosynthetic process
A0016491molecular_functionoxidoreductase activity
A0050660molecular_functionflavin adenine dinucleotide binding
A0051301biological_processcell division
A0071555biological_processcell wall organization
A0071949molecular_functionFAD binding
Functional Information from PROSITE/UniProt
site_idPS00430
Number of Residues89
DetailsTONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. lelqehcslkpyntfgidvrarllahardeadvrealalarerglpllvigggsnllltrdvealvlrmasqgrrivsdaa..................................DSVLVEAE
ChainResidueDetails
ALEU3-GLU91

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00037
ChainResidueDetails
AARG166
AGLU335

site_idSWS_FT_FI2
Number of Residues1
DetailsACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00037
ChainResidueDetails
ASER239

222415

PDB entries from 2024-07-10

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