7OQB

The U2 part of Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1)

Functional Information from GO Data

Chain	GOid	namespace	contents
O	0000245	biological_process	spliceosomal complex assembly
O	0000398	biological_process	mRNA splicing, via spliceosome
O	0000974	cellular_component	Prp19 complex
O	0003729	molecular_function	mRNA binding
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005681	cellular_component	spliceosomal complex
O	0005684	cellular_component	U2-type spliceosomal complex
O	0005686	cellular_component	U2 snRNP
O	0006397	biological_process	mRNA processing
O	0008380	biological_process	RNA splicing
O	0071004	cellular_component	U2-type prespliceosome
O	0071013	cellular_component	catalytic step 2 spliceosome
O	1903241	biological_process	U2-type prespliceosome assembly
P	0000245	biological_process	spliceosomal complex assembly
P	0000398	biological_process	mRNA splicing, via spliceosome
P	0000974	cellular_component	Prp19 complex
P	0003676	molecular_function	nucleic acid binding
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005681	cellular_component	spliceosomal complex
P	0005684	cellular_component	U2-type spliceosomal complex
P	0005686	cellular_component	U2 snRNP
P	0006397	biological_process	mRNA processing
P	0008380	biological_process	RNA splicing
P	0030620	molecular_function	U2 snRNA binding
P	0071004	cellular_component	U2-type prespliceosome
P	1903241	biological_process	U2-type prespliceosome assembly
Q	0000245	biological_process	spliceosomal complex assembly
Q	0000398	biological_process	mRNA splicing, via spliceosome
Q	0000974	cellular_component	Prp19 complex
Q	0003674	molecular_function	molecular_function
Q	0003723	molecular_function	RNA binding
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005681	cellular_component	spliceosomal complex
Q	0005684	cellular_component	U2-type spliceosomal complex
Q	0005686	cellular_component	U2 snRNP
Q	0006397	biological_process	mRNA processing
Q	0071004	cellular_component	U2-type prespliceosome
Q	0071011	cellular_component	precatalytic spliceosome
Q	0071013	cellular_component	catalytic step 2 spliceosome
Q	1903241	biological_process	U2-type prespliceosome assembly
R	0000398	biological_process	mRNA splicing, via spliceosome
R	0003676	molecular_function	nucleic acid binding
R	0003723	molecular_function	RNA binding
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005681	cellular_component	spliceosomal complex
R	0005684	cellular_component	U2-type spliceosomal complex
R	0005686	cellular_component	U2 snRNP
R	0006397	biological_process	mRNA processing
R	0071004	cellular_component	U2-type prespliceosome
R	1903241	biological_process	U2-type prespliceosome assembly
S	0000245	biological_process	spliceosomal complex assembly
S	0000398	biological_process	mRNA splicing, via spliceosome
S	0005634	cellular_component	nucleus
S	0005681	cellular_component	spliceosomal complex
S	0005684	cellular_component	U2-type spliceosomal complex
S	0005686	cellular_component	U2 snRNP
S	0006397	biological_process	mRNA processing
S	0008270	molecular_function	zinc ion binding
S	0008380	biological_process	RNA splicing
S	0009410	biological_process	response to xenobiotic stimulus
S	0071011	cellular_component	precatalytic spliceosome
S	1903241	biological_process	U2-type prespliceosome assembly
T	0000395	biological_process	mRNA 5'-splice site recognition
T	0000398	biological_process	mRNA splicing, via spliceosome
T	0000974	cellular_component	Prp19 complex
T	0003676	molecular_function	nucleic acid binding
T	0003723	molecular_function	RNA binding
T	0005634	cellular_component	nucleus
T	0005681	cellular_component	spliceosomal complex
T	0005686	cellular_component	U2 snRNP
T	0006397	biological_process	mRNA processing
T	0008270	molecular_function	zinc ion binding
T	0008380	biological_process	RNA splicing
T	0046872	molecular_function	metal ion binding
T	0071004	cellular_component	U2-type prespliceosome
T	1903241	biological_process	U2-type prespliceosome assembly
U	0003676	molecular_function	nucleic acid binding
U	0008270	molecular_function	zinc ion binding
V	0000398	biological_process	mRNA splicing, via spliceosome
V	0000974	cellular_component	Prp19 complex
V	0003723	molecular_function	RNA binding
V	0005515	molecular_function	protein binding
V	0005634	cellular_component	nucleus
V	0005681	cellular_component	spliceosomal complex
V	0005686	cellular_component	U2 snRNP
V	0006396	biological_process	RNA processing
V	0006397	biological_process	mRNA processing
V	0008380	biological_process	RNA splicing
V	0045292	biological_process	mRNA cis splicing, via spliceosome
V	0071004	cellular_component	U2-type prespliceosome
V	0071013	cellular_component	catalytic step 2 spliceosome
V	1903241	biological_process	U2-type prespliceosome assembly
W	0000398	biological_process	mRNA splicing, via spliceosome
W	0000974	cellular_component	Prp19 complex
W	0003674	molecular_function	molecular_function
W	0005634	cellular_component	nucleus
W	0005681	cellular_component	spliceosomal complex
W	0005686	cellular_component	U2 snRNP
W	0005737	cellular_component	cytoplasm
W	0006397	biological_process	mRNA processing
W	0008380	biological_process	RNA splicing
W	0030620	molecular_function	U2 snRNA binding
W	0071004	cellular_component	U2-type prespliceosome
W	1903241	biological_process	U2-type prespliceosome assembly
Y	0000398	biological_process	mRNA splicing, via spliceosome
Y	0000974	cellular_component	Prp19 complex
Y	0003676	molecular_function	nucleic acid binding
Y	0003723	molecular_function	RNA binding
Y	0005634	cellular_component	nucleus
Y	0005681	cellular_component	spliceosomal complex
Y	0005686	cellular_component	U2 snRNP
Y	0006397	biological_process	mRNA processing
Y	0008380	biological_process	RNA splicing
Y	0030620	molecular_function	U2 snRNA binding
Y	0071004	cellular_component	U2-type prespliceosome
Y	1903241	biological_process	U2-type prespliceosome assembly
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0000245	biological_process	spliceosomal complex assembly
Z	0000398	biological_process	mRNA splicing, via spliceosome
Z	0003674	molecular_function	molecular_function
Z	0005515	molecular_function	protein binding
Z	0005634	cellular_component	nucleus
Z	0005681	cellular_component	spliceosomal complex
Z	0005684	cellular_component	U2-type spliceosomal complex
Z	0005686	cellular_component	U2 snRNP
Z	0006397	biological_process	mRNA processing
Z	0008380	biological_process	RNA splicing
Z	0071011	cellular_component	precatalytic spliceosome
Z	1903241	biological_process	U2-type prespliceosome assembly
p	0000166	molecular_function	nucleotide binding
p	0000243	cellular_component	commitment complex
p	0000348	biological_process	mRNA branch site recognition
p	0000398	biological_process	mRNA splicing, via spliceosome
p	0003676	molecular_function	nucleic acid binding
p	0003724	molecular_function	RNA helicase activity
p	0004386	molecular_function	helicase activity
p	0005524	molecular_function	ATP binding
p	0005634	cellular_component	nucleus
p	0006397	biological_process	mRNA processing
p	0008186	molecular_function	ATP-dependent activity, acting on RNA
p	0008380	biological_process	RNA splicing
p	0010467	biological_process	gene expression
p	0016787	molecular_function	hydrolase activity
p	0016887	molecular_function	ATP hydrolysis activity
s	0000243	cellular_component	commitment complex
s	0000245	biological_process	spliceosomal complex assembly
s	0000387	biological_process	spliceosomal snRNP assembly
s	0000395	biological_process	mRNA 5'-splice site recognition
s	0000398	biological_process	mRNA splicing, via spliceosome
s	0000974	cellular_component	Prp19 complex
s	0003674	molecular_function	molecular_function
s	0003723	molecular_function	RNA binding
s	0005515	molecular_function	protein binding
s	0005634	cellular_component	nucleus
s	0005681	cellular_component	spliceosomal complex
s	0005682	cellular_component	U5 snRNP
s	0005685	cellular_component	U1 snRNP
s	0005686	cellular_component	U2 snRNP
s	0005687	cellular_component	U4 snRNP
s	0005737	cellular_component	cytoplasm
s	0006397	biological_process	mRNA processing
s	0008380	biological_process	RNA splicing
s	0032991	cellular_component	protein-containing complex
s	0036261	biological_process	7-methylguanosine cap hypermethylation
s	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
s	0070990	molecular_function	snRNP binding
s	0071001	cellular_component	U4/U6 snRNP
s	0071004	cellular_component	U2-type prespliceosome
s	0071013	cellular_component	catalytic step 2 spliceosome
s	1903241	biological_process	U2-type prespliceosome assembly
s	1990904	cellular_component	ribonucleoprotein complex
t	0000243	cellular_component	commitment complex
t	0000245	biological_process	spliceosomal complex assembly
t	0000387	biological_process	spliceosomal snRNP assembly
t	0000395	biological_process	mRNA 5'-splice site recognition
t	0000398	biological_process	mRNA splicing, via spliceosome
t	0000974	cellular_component	Prp19 complex
t	0003723	molecular_function	RNA binding
t	0003729	molecular_function	mRNA binding
t	0005634	cellular_component	nucleus
t	0005681	cellular_component	spliceosomal complex
t	0005682	cellular_component	U5 snRNP
t	0005685	cellular_component	U1 snRNP
t	0005686	cellular_component	U2 snRNP
t	0005687	cellular_component	U4 snRNP
t	0005737	cellular_component	cytoplasm
t	0005829	cellular_component	cytosol
t	0006396	biological_process	RNA processing
t	0006397	biological_process	mRNA processing
t	0008380	biological_process	RNA splicing
t	0030532	cellular_component	small nuclear ribonucleoprotein complex
t	0034715	cellular_component	pICln-Sm protein complex
t	0034719	cellular_component	SMN-Sm protein complex
t	0036261	biological_process	7-methylguanosine cap hypermethylation
t	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
t	0071001	cellular_component	U4/U6 snRNP
t	0071004	cellular_component	U2-type prespliceosome
t	0071011	cellular_component	precatalytic spliceosome
t	0071013	cellular_component	catalytic step 2 spliceosome
t	0097525	cellular_component	spliceosomal snRNP complex
t	0097526	cellular_component	spliceosomal tri-snRNP complex
t	1903241	biological_process	U2-type prespliceosome assembly
t	1990904	cellular_component	ribonucleoprotein complex
u	0000243	cellular_component	commitment complex
u	0000245	biological_process	spliceosomal complex assembly
u	0000387	biological_process	spliceosomal snRNP assembly
u	0000395	biological_process	mRNA 5'-splice site recognition
u	0000398	biological_process	mRNA splicing, via spliceosome
u	0000974	cellular_component	Prp19 complex
u	0003674	molecular_function	molecular_function
u	0003723	molecular_function	RNA binding
u	0005515	molecular_function	protein binding
u	0005634	cellular_component	nucleus
u	0005681	cellular_component	spliceosomal complex
u	0005682	cellular_component	U5 snRNP
u	0005685	cellular_component	U1 snRNP
u	0005686	cellular_component	U2 snRNP
u	0005687	cellular_component	U4 snRNP
u	0005737	cellular_component	cytoplasm
u	0005829	cellular_component	cytosol
u	0006397	biological_process	mRNA processing
u	0008150	biological_process	biological_process
u	0008380	biological_process	RNA splicing
u	0030532	cellular_component	small nuclear ribonucleoprotein complex
u	0034715	cellular_component	pICln-Sm protein complex
u	0036261	biological_process	7-methylguanosine cap hypermethylation
u	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
u	0071001	cellular_component	U4/U6 snRNP
u	0071004	cellular_component	U2-type prespliceosome
u	0071011	cellular_component	precatalytic spliceosome
u	0071013	cellular_component	catalytic step 2 spliceosome
u	1903241	biological_process	U2-type prespliceosome assembly
u	1990904	cellular_component	ribonucleoprotein complex
v	0000243	cellular_component	commitment complex
v	0000245	biological_process	spliceosomal complex assembly
v	0000387	biological_process	spliceosomal snRNP assembly
v	0000395	biological_process	mRNA 5'-splice site recognition
v	0000398	biological_process	mRNA splicing, via spliceosome
v	0000974	cellular_component	Prp19 complex
v	0003723	molecular_function	RNA binding
v	0003729	molecular_function	mRNA binding
v	0005515	molecular_function	protein binding
v	0005634	cellular_component	nucleus
v	0005681	cellular_component	spliceosomal complex
v	0005682	cellular_component	U5 snRNP
v	0005685	cellular_component	U1 snRNP
v	0005686	cellular_component	U2 snRNP
v	0005687	cellular_component	U4 snRNP
v	0005737	cellular_component	cytoplasm
v	0005829	cellular_component	cytosol
v	0006396	biological_process	RNA processing
v	0006397	biological_process	mRNA processing
v	0008380	biological_process	RNA splicing
v	0034719	cellular_component	SMN-Sm protein complex
v	0036261	biological_process	7-methylguanosine cap hypermethylation
v	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
v	0071001	cellular_component	U4/U6 snRNP
v	0071004	cellular_component	U2-type prespliceosome
v	0071011	cellular_component	precatalytic spliceosome
v	0071013	cellular_component	catalytic step 2 spliceosome
v	0097526	cellular_component	spliceosomal tri-snRNP complex
v	1903241	biological_process	U2-type prespliceosome assembly
v	1990904	cellular_component	ribonucleoprotein complex
w	0000243	cellular_component	commitment complex
w	0000245	biological_process	spliceosomal complex assembly
w	0000387	biological_process	spliceosomal snRNP assembly
w	0000395	biological_process	mRNA 5'-splice site recognition
w	0000398	biological_process	mRNA splicing, via spliceosome
w	0003723	molecular_function	RNA binding
w	0005515	molecular_function	protein binding
w	0005634	cellular_component	nucleus
w	0005681	cellular_component	spliceosomal complex
w	0005682	cellular_component	U5 snRNP
w	0005685	cellular_component	U1 snRNP
w	0005686	cellular_component	U2 snRNP
w	0005687	cellular_component	U4 snRNP
w	0005737	cellular_component	cytoplasm
w	0006397	biological_process	mRNA processing
w	0008380	biological_process	RNA splicing
w	0032991	cellular_component	protein-containing complex
w	0034715	cellular_component	pICln-Sm protein complex
w	0036261	biological_process	7-methylguanosine cap hypermethylation
w	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
w	0071001	cellular_component	U4/U6 snRNP
w	0071004	cellular_component	U2-type prespliceosome
w	0071011	cellular_component	precatalytic spliceosome
w	1903241	biological_process	U2-type prespliceosome assembly
w	1990904	cellular_component	ribonucleoprotein complex
w	1990935	molecular_function	splicing factor binding
x	0000243	cellular_component	commitment complex
x	0000245	biological_process	spliceosomal complex assembly
x	0000387	biological_process	spliceosomal snRNP assembly
x	0000395	biological_process	mRNA 5'-splice site recognition
x	0000398	biological_process	mRNA splicing, via spliceosome
x	0000974	cellular_component	Prp19 complex
x	0003723	molecular_function	RNA binding
x	0005515	molecular_function	protein binding
x	0005634	cellular_component	nucleus
x	0005681	cellular_component	spliceosomal complex
x	0005682	cellular_component	U5 snRNP
x	0005685	cellular_component	U1 snRNP
x	0005686	cellular_component	U2 snRNP
x	0005687	cellular_component	U4 snRNP
x	0005737	cellular_component	cytoplasm
x	0006397	biological_process	mRNA processing
x	0008266	molecular_function	poly(U) RNA binding
x	0008380	biological_process	RNA splicing
x	0034715	cellular_component	pICln-Sm protein complex
x	0036261	biological_process	7-methylguanosine cap hypermethylation
x	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
x	0071001	cellular_component	U4/U6 snRNP
x	0071013	cellular_component	catalytic step 2 spliceosome
x	0120114	cellular_component	Sm-like protein family complex
x	1903241	biological_process	U2-type prespliceosome assembly
x	1990904	cellular_component	ribonucleoprotein complex
x	1990935	molecular_function	splicing factor binding
y	0000243	cellular_component	commitment complex
y	0000245	biological_process	spliceosomal complex assembly
y	0000387	biological_process	spliceosomal snRNP assembly
y	0000395	biological_process	mRNA 5'-splice site recognition
y	0000398	biological_process	mRNA splicing, via spliceosome
y	0003674	molecular_function	molecular_function
y	0003723	molecular_function	RNA binding
y	0005515	molecular_function	protein binding
y	0005634	cellular_component	nucleus
y	0005681	cellular_component	spliceosomal complex
y	0005682	cellular_component	U5 snRNP
y	0005685	cellular_component	U1 snRNP
y	0005686	cellular_component	U2 snRNP
y	0005687	cellular_component	U4 snRNP
y	0005737	cellular_component	cytoplasm
y	0006397	biological_process	mRNA processing
y	0008150	biological_process	biological_process
y	0008380	biological_process	RNA splicing
y	0032991	cellular_component	protein-containing complex
y	0034719	cellular_component	SMN-Sm protein complex
y	0036261	biological_process	7-methylguanosine cap hypermethylation
y	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
y	0071001	cellular_component	U4/U6 snRNP
y	0071004	cellular_component	U2-type prespliceosome
y	0071011	cellular_component	precatalytic spliceosome
y	0071013	cellular_component	catalytic step 2 spliceosome
y	0097526	cellular_component	spliceosomal tri-snRNP complex
y	1903241	biological_process	U2-type prespliceosome assembly
y	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	23
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cpf..CsrwFktssvfesHlvgkiH

Chain	Residue	Details
T	CYS282-HIS304

---

site_id	PS00039
Number of Residues	9
Details	DEAD_ATP_HELICASE DEAD-box subfamily ATP-dependent helicases signature. VMDEADRlF

Chain	Residue	Details
p	VAL413-PHE421

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	38
Details	Repeat: {"description":"HEAT 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	37
Details	Repeat: {"description":"HEAT 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	37
Details	Repeat: {"description":"HEAT 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	37
Details	Repeat: {"description":"HEAT 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	37
Details	Repeat: {"description":"HEAT 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	37
Details	Repeat: {"description":"HEAT 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	37
Details	Repeat: {"description":"HEAT 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	37
Details	Repeat: {"description":"HEAT 8"}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	38
Details	Repeat: {"description":"HEAT 9"}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	30
Details	Zinc finger: {"description":"Matrin-type"}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	40
Details	Repeat: {"description":"SURP motif 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	30
Details	Zinc finger: {"description":"Matrin-type 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00130","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	31
Details	Zinc finger: {"description":"Matrin-type 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00130","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	9
Details	Compositional bias: {"description":"Acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	21
Details	Repeat: {"description":"LRR 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	20
Details	Repeat: {"description":"LRR 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	21
Details	Repeat: {"description":"LRR 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	38
Details	Domain: {"description":"LRRCT"}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	78
Details	Domain: {"description":"RRM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00176","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	72
Details	Domain: {"description":"Sm","evidences":[{"source":"PROSITE-ProRule","id":"PRU01346","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	180
Details	Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	3
Details	Motif: {"description":"DEAD box"}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---