7OQ8

Ternary complex of 14-3-3 sigma, Estrogen Receptor alfa phosphopeptide, and WQ178

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0001836	biological_process	release of cytochrome c from mitochondria
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006469	biological_process	negative regulation of protein kinase activity
C	0006611	biological_process	protein export from nucleus
C	0007165	biological_process	signal transduction
C	0008104	biological_process	intracellular protein localization
C	0008426	molecular_function	protein kinase C inhibitor activity
C	0008630	biological_process	intrinsic apoptotic signaling pathway in response to DNA damage
C	0010482	biological_process	regulation of epidermal cell division
C	0019901	molecular_function	protein kinase binding
C	0022407	biological_process	regulation of cell-cell adhesion
C	0030307	biological_process	positive regulation of cell growth
C	0032880	biological_process	regulation of protein localization
C	0042802	molecular_function	identical protein binding
C	0045296	molecular_function	cadherin binding
C	0045606	biological_process	positive regulation of epidermal cell differentiation
C	0045785	biological_process	positive regulation of cell adhesion
C	0045824	biological_process	negative regulation of innate immune response
C	0046827	biological_process	positive regulation of protein export from nucleus
C	0050815	molecular_function	phosphoserine residue binding
C	0051219	molecular_function	phosphoprotein binding
C	0061436	biological_process	establishment of skin barrier
C	0070062	cellular_component	extracellular exosome
C	0140311	molecular_function	protein sequestering activity
C	0141156	biological_process	cAMP/PKA signal transduction
C	1903077	biological_process	negative regulation of protein localization to plasma membrane
C	1903829	biological_process	positive regulation of protein localization

Functional Information from PROSITE/UniProt

site_id	PS00796
Number of Residues	11
Details	1433_1 14-3-3 proteins signature 1. RNLLSVAYKNV

Chain	Residue	Details
C	ARG41-VAL51

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site_id	PS00797
Number of Residues	20
Details	1433_2 14-3-3 proteins signature 2. YKDSTLIMQLLRDNLTLWTA

Chain	Residue	Details
C	TYR213-ALA232

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Site: {"description":"Interaction with phosphoserine on interacting protein"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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