7OKK

Crystal structure of human BCL6 BTB domain in complex with compound 12e

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	binding site for residue VH8 A 201

Chain	Residue
A	ASN21
A	SER59
A	GLN113
A	MET114
A	GLU115
A	HOH303
A	HOH313
A	ARG24
A	LEU25
A	MET51
A	ALA52
A	CYS53
A	SER54
A	GLY55
A	TYR58

---

site_id	AC2
Number of Residues	5
Details	binding site for residue EDO A 202

Chain	Residue
A	ILE72
A	ASN73
A	HOH319
A	HOH350
B	TRP1

---

site_id	AC3
Number of Residues	4
Details	binding site for residue EDO A 203

Chain	Residue
A	GLU99
A	ILE125
A	HOH302
A	HOH308

---

site_id	AC4
Number of Residues	2
Details	binding site for residue EDO A 204

Chain	Residue
A	PHE43
A	GLU81

---

site_id	AC5
Number of Residues	4
Details	binding site for residue CL A 205

Chain	Residue
A	MET114
A	HIS116
A	HOH313
A	HOH335

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	67
Details	Domain: {"description":"BTB","evidences":[{"source":"PROSITE-ProRule","id":"PRU00037","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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