7OKF

Crystal structure of human BCL6 BTB domain in complex with compound 8c

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	binding site for residue VH5 A 201

Chain	Residue
A	ASN21
A	TYR58
A	GLN113
A	GLU115
A	DMS207
A	HOH302
A	HOH305
A	HOH386
A	HOH390
A	ARG24
A	LEU25
A	ARG28
A	MET51
A	ALA52
A	CYS53
A	SER54
A	GLY55

---

site_id	AC2
Number of Residues	4
Details	binding site for residue EDO A 202

Chain	Residue
A	ASP63
A	GLN64
A	ARG98
A	GLU99

---

site_id	AC3
Number of Residues	2
Details	binding site for residue EDO A 203

Chain	Residue
A	GLU99
A	SER128

---

site_id	AC4
Number of Residues	2
Details	binding site for residue EDO A 204

Chain	Residue
A	GLN42
A	HOH316

---

site_id	AC5
Number of Residues	5
Details	binding site for residue EDO A 205

Chain	Residue
A	TYR58
A	SER59
A	THR62
A	HOH305
A	HOH347

---

site_id	AC6
Number of Residues	3
Details	binding site for residue EDO A 206

Chain	Residue
A	TYR111
A	HOH403
B	ALA5

---

site_id	AC7
Number of Residues	2
Details	binding site for residue DMS A 207

Chain	Residue
A	VH5201
A	HOH324

---

site_id	AC8
Number of Residues	3
Details	binding site for residue DMS A 209

Chain	Residue
A	SER27
A	HOH304
A	HOH351

---

site_id	AC9
Number of Residues	4
Details	binding site for residue CL A 210

Chain	Residue
A	MET114
A	HIS116
A	VAL117
A	HOH386

---

site_id	AD1
Number of Residues	1
Details	binding site for residue CL A 211

Chain	Residue
A	SER70

---

site_id	AD2
Number of Residues	4
Details	binding site for residue EDO B 101

Chain	Residue
A	ILE72
A	ASN73
A	HOH371
B	TRP1

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	67
Details	Domain: {"description":"BTB","evidences":[{"source":"PROSITE-ProRule","id":"PRU00037","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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