7OKE

Crystal structure of human BCL6 BTB domain in complex with compound 2

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue VHQ A 201

Chain	Residue
A	ASN21
A	GLN113
A	MET114
A	GLU115
A	CL208
A	ARG24
A	LEU25
A	MET51
A	ALA52
A	CYS53
A	SER54
A	GLY55
A	TYR58

---

site_id	AC2
Number of Residues	4
Details	binding site for residue EDO A 202

Chain	Residue
A	ASP63
A	GLN64
A	ARG98
A	GLU99

---

site_id	AC3
Number of Residues	4
Details	binding site for residue EDO A 203

Chain	Residue
A	TYR111
A	HOH369
A	HOH407
B	ALA5

---

site_id	AC4
Number of Residues	2
Details	binding site for residue EDO A 204

Chain	Residue
A	GLU81
A	HOH326

---

site_id	AC5
Number of Residues	5
Details	binding site for residue EDO A 205

Chain	Residue
A	ARG26
A	PHE43
A	ARG44
A	LEU87
A	HOH312

---

site_id	AC6
Number of Residues	3
Details	binding site for residue EDO A 206

Chain	Residue
A	LEU69
A	SER70
A	VAL71

---

site_id	AC7
Number of Residues	8
Details	binding site for residue EDO A 207

Chain	Residue
A	ASP6
A	SER7
A	CYS8
A	SER59
A	ILE60
A	HOH315
A	HOH316
A	HOH317

---

site_id	AC8
Number of Residues	4
Details	binding site for residue CL A 208

Chain	Residue
A	MET114
A	HIS116
A	VHQ201
A	HOH361

---

site_id	AC9
Number of Residues	4
Details	binding site for residue DMS A 209

Chain	Residue
A	VAL35
A	GLN42
A	VAL71
A	HOH339

---

site_id	AD1
Number of Residues	4
Details	binding site for residue DMS A 210

Chain	Residue
A	LEU65
A	GLU99
A	ILE102
A	MET103

---

site_id	AD2
Number of Residues	5
Details	binding site for residue EDO B 101

Chain	Residue
A	ILE72
A	ASN73
A	PHE124
B	TRP1
B	HOH201

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	67
Details	Domain: {"description":"BTB","evidences":[{"source":"PROSITE-ProRule","id":"PRU00037","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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