Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7OKB

Crystal structure of Pseudomonas aeruginosa LpxA in complex with compound 45

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0006629	biological_process	lipid metabolic process
A	0008610	biological_process	lipid biosynthetic process
A	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
A	0009245	biological_process	lipid A biosynthetic process
A	0016020	cellular_component	membrane
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
B	0005737	cellular_component	cytoplasm
B	0006629	biological_process	lipid metabolic process
B	0008610	biological_process	lipid biosynthetic process
B	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
B	0009245	biological_process	lipid A biosynthetic process
B	0016020	cellular_component	membrane
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
C	0005737	cellular_component	cytoplasm
C	0006629	biological_process	lipid metabolic process
C	0008610	biological_process	lipid biosynthetic process
C	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
C	0009245	biological_process	lipid A biosynthetic process
C	0016020	cellular_component	membrane
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
D	0005737	cellular_component	cytoplasm
D	0006629	biological_process	lipid metabolic process
D	0008610	biological_process	lipid biosynthetic process
D	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
D	0009245	biological_process	lipid A biosynthetic process
D	0016020	cellular_component	membrane
D	0016740	molecular_function	transferase activity
D	0016746	molecular_function	acyltransferase activity
E	0005737	cellular_component	cytoplasm
E	0006629	biological_process	lipid metabolic process
E	0008610	biological_process	lipid biosynthetic process
E	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
E	0009245	biological_process	lipid A biosynthetic process
E	0016020	cellular_component	membrane
E	0016740	molecular_function	transferase activity
E	0016746	molecular_function	acyltransferase activity
F	0005737	cellular_component	cytoplasm
F	0006629	biological_process	lipid metabolic process
F	0008610	biological_process	lipid biosynthetic process
F	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
F	0009245	biological_process	lipid A biosynthetic process
F	0016020	cellular_component	membrane
F	0016740	molecular_function	transferase activity
F	0016746	molecular_function	acyltransferase activity
G	0005737	cellular_component	cytoplasm
G	0006629	biological_process	lipid metabolic process
G	0008610	biological_process	lipid biosynthetic process
G	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
G	0009245	biological_process	lipid A biosynthetic process
G	0016020	cellular_component	membrane
G	0016740	molecular_function	transferase activity
G	0016746	molecular_function	acyltransferase activity
H	0005737	cellular_component	cytoplasm
H	0006629	biological_process	lipid metabolic process
H	0008610	biological_process	lipid biosynthetic process
H	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
H	0009245	biological_process	lipid A biosynthetic process
H	0016020	cellular_component	membrane
H	0016740	molecular_function	transferase activity
H	0016746	molecular_function	acyltransferase activity
I	0005737	cellular_component	cytoplasm
I	0006629	biological_process	lipid metabolic process
I	0008610	biological_process	lipid biosynthetic process
I	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
I	0009245	biological_process	lipid A biosynthetic process
I	0016020	cellular_component	membrane
I	0016740	molecular_function	transferase activity
I	0016746	molecular_function	acyltransferase activity
J	0005737	cellular_component	cytoplasm
J	0006629	biological_process	lipid metabolic process
J	0008610	biological_process	lipid biosynthetic process
J	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
J	0009245	biological_process	lipid A biosynthetic process
J	0016020	cellular_component	membrane
J	0016740	molecular_function	transferase activity
J	0016746	molecular_function	acyltransferase activity
K	0005737	cellular_component	cytoplasm
K	0006629	biological_process	lipid metabolic process
K	0008610	biological_process	lipid biosynthetic process
K	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
K	0009245	biological_process	lipid A biosynthetic process
K	0016020	cellular_component	membrane
K	0016740	molecular_function	transferase activity
K	0016746	molecular_function	acyltransferase activity
L	0005737	cellular_component	cytoplasm
L	0006629	biological_process	lipid metabolic process
L	0008610	biological_process	lipid biosynthetic process
L	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
L	0009245	biological_process	lipid A biosynthetic process
L	0016020	cellular_component	membrane
L	0016740	molecular_function	transferase activity
L	0016746	molecular_function	acyltransferase activity
M	0005737	cellular_component	cytoplasm
M	0006629	biological_process	lipid metabolic process
M	0008610	biological_process	lipid biosynthetic process
M	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
M	0009245	biological_process	lipid A biosynthetic process
M	0016020	cellular_component	membrane
M	0016740	molecular_function	transferase activity
M	0016746	molecular_function	acyltransferase activity
N	0005737	cellular_component	cytoplasm
N	0006629	biological_process	lipid metabolic process
N	0008610	biological_process	lipid biosynthetic process
N	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
N	0009245	biological_process	lipid A biosynthetic process
N	0016020	cellular_component	membrane
N	0016740	molecular_function	transferase activity
N	0016746	molecular_function	acyltransferase activity
O	0005737	cellular_component	cytoplasm
O	0006629	biological_process	lipid metabolic process
O	0008610	biological_process	lipid biosynthetic process
O	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
O	0009245	biological_process	lipid A biosynthetic process
O	0016020	cellular_component	membrane
O	0016740	molecular_function	transferase activity
O	0016746	molecular_function	acyltransferase activity
P	0005737	cellular_component	cytoplasm
P	0006629	biological_process	lipid metabolic process
P	0008610	biological_process	lipid biosynthetic process
P	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
P	0009245	biological_process	lipid A biosynthetic process
P	0016020	cellular_component	membrane
P	0016740	molecular_function	transferase activity
P	0016746	molecular_function	acyltransferase activity
Q	0005737	cellular_component	cytoplasm
Q	0006629	biological_process	lipid metabolic process
Q	0008610	biological_process	lipid biosynthetic process
Q	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
Q	0009245	biological_process	lipid A biosynthetic process
Q	0016020	cellular_component	membrane
Q	0016740	molecular_function	transferase activity
Q	0016746	molecular_function	acyltransferase activity
R	0005737	cellular_component	cytoplasm
R	0006629	biological_process	lipid metabolic process
R	0008610	biological_process	lipid biosynthetic process
R	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
R	0009245	biological_process	lipid A biosynthetic process
R	0016020	cellular_component	membrane
R	0016740	molecular_function	transferase activity
R	0016746	molecular_function	acyltransferase activity
S	0005737	cellular_component	cytoplasm
S	0006629	biological_process	lipid metabolic process
S	0008610	biological_process	lipid biosynthetic process
S	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
S	0009245	biological_process	lipid A biosynthetic process
S	0016020	cellular_component	membrane
S	0016740	molecular_function	transferase activity
S	0016746	molecular_function	acyltransferase activity
T	0005737	cellular_component	cytoplasm
T	0006629	biological_process	lipid metabolic process
T	0008610	biological_process	lipid biosynthetic process
T	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
T	0009245	biological_process	lipid A biosynthetic process
T	0016020	cellular_component	membrane
T	0016740	molecular_function	transferase activity
T	0016746	molecular_function	acyltransferase activity
U	0005737	cellular_component	cytoplasm
U	0006629	biological_process	lipid metabolic process
U	0008610	biological_process	lipid biosynthetic process
U	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
U	0009245	biological_process	lipid A biosynthetic process
U	0016020	cellular_component	membrane
U	0016740	molecular_function	transferase activity
U	0016746	molecular_function	acyltransferase activity
V	0005737	cellular_component	cytoplasm
V	0006629	biological_process	lipid metabolic process
V	0008610	biological_process	lipid biosynthetic process
V	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
V	0009245	biological_process	lipid A biosynthetic process
V	0016020	cellular_component	membrane
V	0016740	molecular_function	transferase activity
V	0016746	molecular_function	acyltransferase activity
W	0005737	cellular_component	cytoplasm
W	0006629	biological_process	lipid metabolic process
W	0008610	biological_process	lipid biosynthetic process
W	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
W	0009245	biological_process	lipid A biosynthetic process
W	0016020	cellular_component	membrane
W	0016740	molecular_function	transferase activity
W	0016746	molecular_function	acyltransferase activity
X	0005737	cellular_component	cytoplasm
X	0006629	biological_process	lipid metabolic process
X	0008610	biological_process	lipid biosynthetic process
X	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
X	0009245	biological_process	lipid A biosynthetic process
X	0016020	cellular_component	membrane
X	0016740	molecular_function	transferase activity
X	0016746	molecular_function	acyltransferase activity
Y	0005737	cellular_component	cytoplasm
Y	0006629	biological_process	lipid metabolic process
Y	0008610	biological_process	lipid biosynthetic process
Y	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
Y	0009245	biological_process	lipid A biosynthetic process
Y	0016020	cellular_component	membrane
Y	0016740	molecular_function	transferase activity
Y	0016746	molecular_function	acyltransferase activity
Z	0005737	cellular_component	cytoplasm
Z	0006629	biological_process	lipid metabolic process
Z	0008610	biological_process	lipid biosynthetic process
Z	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
Z	0009245	biological_process	lipid A biosynthetic process
Z	0016020	cellular_component	membrane
Z	0016740	molecular_function	transferase activity
Z	0016746	molecular_function	acyltransferase activity
a	0005737	cellular_component	cytoplasm
a	0006629	biological_process	lipid metabolic process
a	0008610	biological_process	lipid biosynthetic process
a	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
a	0009245	biological_process	lipid A biosynthetic process
a	0016020	cellular_component	membrane
a	0016740	molecular_function	transferase activity
a	0016746	molecular_function	acyltransferase activity
b	0005737	cellular_component	cytoplasm
b	0006629	biological_process	lipid metabolic process
b	0008610	biological_process	lipid biosynthetic process
b	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
b	0009245	biological_process	lipid A biosynthetic process
b	0016020	cellular_component	membrane
b	0016740	molecular_function	transferase activity
b	0016746	molecular_function	acyltransferase activity
c	0005737	cellular_component	cytoplasm
c	0006629	biological_process	lipid metabolic process
c	0008610	biological_process	lipid biosynthetic process
c	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
c	0009245	biological_process	lipid A biosynthetic process
c	0016020	cellular_component	membrane
c	0016740	molecular_function	transferase activity
c	0016746	molecular_function	acyltransferase activity
d	0005737	cellular_component	cytoplasm
d	0006629	biological_process	lipid metabolic process
d	0008610	biological_process	lipid biosynthetic process
d	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
d	0009245	biological_process	lipid A biosynthetic process
d	0016020	cellular_component	membrane
d	0016740	molecular_function	transferase activity
d	0016746	molecular_function	acyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue CL A 301

Chain	Residue
A	HIS209
A	ARG213

site_id	AC2
Number of Residues	1
Details	binding site for residue CL A 302

Chain	Residue
A	HIS142

site_id	AC3
Number of Residues	2
Details	binding site for residue CL A 303

Chain	Residue
A	LYS216
A	ARG220

site_id	AC4
Number of Residues	1
Details	binding site for residue CL A 305

Chain	Residue
A	HIS128

site_id	AC5
Number of Residues	5
Details	binding site for residue SO4 A 307

Chain	Residue
A	VFZ310
B	HIS156
A	GLY168
A	MET169
A	PHE184

site_id	AC6
Number of Residues	5
Details	binding site for residue SO4 A 308

Chain	Residue
A	TRP25
B	TRP25
C	ARG7
C	TRP25
D	SO4303

site_id	AC7
Number of Residues	3
Details	binding site for residue SO4 A 309

Chain	Residue
A	THR182
A	ASN194
A	GLU196

site_id	AC8
Number of Residues	9
Details	binding site for residue VFZ A 310

Chain	Residue
A	VAL132
A	ASN133
A	SER150
A	GLY151
A	PHE166
A	MET169
A	SO4307
B	ALA138
B	GLN157

site_id	AC9
Number of Residues	2
Details	binding site for residue CL B 301

Chain	Residue
B	HIS209
B	ARG213

site_id	AD1
Number of Residues	2
Details	binding site for residue CL B 302

Chain	Residue
B	SER192
B	ARG212

site_id	AD2
Number of Residues	5
Details	binding site for residue SO4 B 303

Chain	Residue
B	GLY168
B	MET169
B	PHE184
B	VFZ305
C	HIS156

site_id	AD3
Number of Residues	4
Details	binding site for residue SO4 B 304

Chain	Residue
B	PHE166
B	THR182
B	ASN194
B	GLU196

site_id	AD4
Number of Residues	10
Details	binding site for residue VFZ B 305

Chain	Residue
B	VAL132
B	ASN133
B	SER150
B	GLY151
B	MET169
B	SO4303
C	LEU71
C	HIS118
C	ALA138
C	GLN157

site_id	AD5
Number of Residues	2
Details	binding site for residue CL C 301

Chain	Residue
C	HIS209
C	ARG213

site_id	AD6
Number of Residues	2
Details	binding site for residue CL C 302

Chain	Residue
C	LYS216
C	ARG220

site_id	AD7
Number of Residues	1
Details	binding site for residue CL C 303

Chain	Residue
C	ARG212

site_id	AD8
Number of Residues	5
Details	binding site for residue SO4 C 304

Chain	Residue
A	HIS156
C	GLY168
C	MET169
C	PHE184
C	VFZ306

site_id	AD9
Number of Residues	2
Details	binding site for residue SO4 C 305

Chain	Residue
C	THR182
C	ASN194

site_id	AE1
Number of Residues	10
Details	binding site for residue VFZ C 306

Chain	Residue
A	LEU71
A	ALA138
A	HIS156
C	MET114
C	VAL132
C	ASN133
C	SER150
C	GLY151
C	MET169
C	SO4304

site_id	AE2
Number of Residues	2
Details	binding site for residue CL D 301

Chain	Residue
D	HIS209
D	ARG213

site_id	AE3
Number of Residues	5
Details	binding site for residue SO4 D 302

Chain	Residue
D	GLY168
D	MET169
D	PHE184
D	VFZ305
E	HIS156

site_id	AE4
Number of Residues	6
Details	binding site for residue SO4 D 303

Chain	Residue
A	SO4308
D	ARG7
D	TRP25
E	TRP25
F	ARG7
F	TRP25

site_id	AE5
Number of Residues	3
Details	binding site for residue SO4 D 304

Chain	Residue
D	THR182
D	ASN194
D	GLU196

site_id	AE6
Number of Residues	9
Details	binding site for residue VFZ D 305

Chain	Residue
D	VAL132
D	ASN133
D	SER150
D	GLY151
D	PHE166
D	MET169
D	SO4302
E	HIS118
E	ALA138

site_id	AE7
Number of Residues	2
Details	binding site for residue CL E 301

Chain	Residue
E	ARG213
E	HIS209

site_id	AE8
Number of Residues	1
Details	binding site for residue CL E 302

Chain	Residue
E	HIS128

site_id	AE9
Number of Residues	5
Details	binding site for residue SO4 E 303

Chain	Residue
E	GLY168
E	MET169
E	PHE184
E	VFZ305
F	HIS156

site_id	AF1
Number of Residues	5
Details	binding site for residue SO4 E 304

Chain	Residue
E	PHE166
E	THR182
E	ASN194
E	GLU196
E	HOH403

site_id	AF2
Number of Residues	11
Details	binding site for residue VFZ E 305

Chain	Residue
E	VAL132
E	ASN133
E	SER150
E	GLY151
E	PHE166
E	MET169
E	SO4303
F	LEU71
F	ALA136
F	ALA138
F	GLN157

site_id	AF3
Number of Residues	5
Details	binding site for residue SO4 F 301

Chain	Residue
D	HIS156
F	GLY168
F	MET169
F	PHE184
F	VFZ303

site_id	AF4
Number of Residues	2
Details	binding site for residue SO4 F 302

Chain	Residue
F	PHE166
F	ASN194

site_id	AF5
Number of Residues	10
Details	binding site for residue VFZ F 303

Chain	Residue
D	LEU71
D	ALA138
D	GLN157
F	MET114
F	VAL132
F	ASN133
F	SER150
F	GLY151
F	MET169
F	SO4301

site_id	AF6
Number of Residues	2
Details	binding site for residue CL G 301

Chain	Residue
G	HIS209
G	ARG213

site_id	AF7
Number of Residues	5
Details	binding site for residue SO4 G 302

Chain	Residue
G	TRP25
H	ARG7
H	TRP25
I	ARG7
I	TRP25

site_id	AF8
Number of Residues	5
Details	binding site for residue SO4 G 303

Chain	Residue
G	GLY168
G	MET169
G	PHE184
G	VFZ304
H	HIS156

site_id	AF9
Number of Residues	10
Details	binding site for residue VFZ G 304

Chain	Residue
G	VAL132
G	ASN133
G	SER150
G	GLY151
G	SO4303
H	ASP70
H	LEU71
H	HIS118
H	ALA138
H	HIS156

site_id	AG1
Number of Residues	6
Details	binding site for residue SO4 H 301

Chain	Residue
H	SER150
H	GLY168
H	MET169
H	PHE184
H	VFZ303
I	HIS156

site_id	AG2
Number of Residues	4
Details	binding site for residue SO4 H 302

Chain	Residue
H	PHE166
H	THR182
H	ASN194
H	GLU196

site_id	AG3
Number of Residues	8
Details	binding site for residue VFZ H 303

Chain	Residue
H	VAL132
H	ASN133
H	SER150
H	GLY151
H	MET169
H	SO4301
I	ALA138
I	HIS156

site_id	AG4
Number of Residues	2
Details	binding site for residue CL I 301

Chain	Residue
I	HIS209
I	ARG213

site_id	AG5
Number of Residues	5
Details	binding site for residue SO4 I 302

Chain	Residue
G	HIS156
I	GLY168
I	MET169
I	PHE184
I	VFZ304

site_id	AG6
Number of Residues	3
Details	binding site for residue SO4 I 303

Chain	Residue
I	PHE166
I	THR182
I	ASN194

site_id	AG7
Number of Residues	10
Details	binding site for residue VFZ I 304

Chain	Residue
G	LEU71
G	ALA138
G	HIS156
I	MET114
I	VAL132
I	ASN133
I	SER150
I	GLY151
I	MET169
I	SO4302

site_id	AG8
Number of Residues	2
Details	binding site for residue CL M 301

Chain	Residue
M	LYS216
M	ARG220

site_id	AG9
Number of Residues	2
Details	binding site for residue CL M 302

Chain	Residue
M	HIS209
M	ARG213

site_id	AH1
Number of Residues	5
Details	binding site for residue SO4 M 303

Chain	Residue
M	GLY168
M	MET169
M	PHE184
M	VFZ304
N	HIS156

site_id	AH2
Number of Residues	11
Details	binding site for residue VFZ M 304

Chain	Residue
M	VAL132
M	ASN133
M	SER150
M	GLY151
M	MET169
M	SO4303
N	ASP70
N	LEU71
N	HIS118
N	ALA138
N	HIS156

site_id	AH3
Number of Residues	2
Details	binding site for residue CL N 301

Chain	Residue
N	LYS216
N	ARG220

site_id	AH4
Number of Residues	5
Details	binding site for residue SO4 N 302

Chain	Residue
N	GLY168
N	MET169
N	PHE184
N	VFZ305
O	HIS156

site_id	AH5
Number of Residues	2
Details	binding site for residue SO4 N 303

Chain	Residue
N	THR182
N	ASN194

site_id	AH6
Number of Residues	5
Details	binding site for residue SO4 N 304

Chain	Residue
M	ARG7
M	TRP25
N	ARG7
N	TRP25
O	TRP25

site_id	AH7
Number of Residues	9
Details	binding site for residue VFZ N 305

Chain	Residue
N	MET114
N	VAL132
N	ASN133
N	SER150
N	GLY151
N	MET169
N	SO4302
O	ALA138
O	GLN157

site_id	AH8
Number of Residues	2
Details	binding site for residue CL O 301

Chain	Residue
O	HIS209
O	ARG213

site_id	AH9
Number of Residues	5
Details	binding site for residue SO4 O 302

Chain	Residue
M	HIS156
O	GLY168
O	MET169
O	PHE184
O	VFZ303

site_id	AI1
Number of Residues	10
Details	binding site for residue VFZ O 303

Chain	Residue
M	LEU71
M	HIS118
M	ALA138
M	HIS156
O	MET114
O	VAL132
O	ASN133
O	SER150
O	GLY151
O	SO4302

site_id	AI2
Number of Residues	6
Details	binding site for residue SO4 J 301

Chain	Residue
J	SER150
J	GLY168
J	MET169
J	PHE184
J	VFZ303
K	HIS156

site_id	AI3
Number of Residues	5
Details	binding site for residue SO4 J 302

Chain	Residue
J	ARG7
J	TRP25
K	ARG7
K	TRP25
L	TRP25

site_id	AI4
Number of Residues	10
Details	binding site for residue VFZ J 303

Chain	Residue
J	VAL132
J	ASN133
J	SER150
J	GLY151
J	MET169
J	SO4301
K	HIS118
K	ALA138
K	HIS156
K	GLN157

site_id	AI5
Number of Residues	4
Details	binding site for residue SO4 K 301

Chain	Residue
K	GLY168
K	MET169
K	PHE184
K	VFZ303

site_id	AI6
Number of Residues	2
Details	binding site for residue SO4 K 302

Chain	Residue
K	PHE166
K	ASN194

site_id	AI7
Number of Residues	12
Details	binding site for residue VFZ K 303

Chain	Residue
K	VAL132
K	ASN133
K	SER150
K	GLY151
K	PHE166
K	MET169
K	SO4301
L	ASP70
L	LEU71
L	HIS118
L	ALA138
L	HIS156

site_id	AI8
Number of Residues	2
Details	binding site for residue CL L 301

Chain	Residue
L	HIS209
L	ARG213

site_id	AI9
Number of Residues	5
Details	binding site for residue SO4 L 302

Chain	Residue
J	HIS156
L	GLY168
L	MET169
L	PHE184
L	VFZ303

site_id	AJ1
Number of Residues	10
Details	binding site for residue VFZ L 303

Chain	Residue
J	LEU71
J	ALA138
J	HIS156
L	MET114
L	VAL132
L	ASN133
L	SER150
L	GLY151
L	MET169
L	SO4302

site_id	AJ2
Number of Residues	5
Details	binding site for residue SO4 P 301

Chain	Residue
P	GLY168
P	MET169
P	PHE184
P	VFZ304
Q	HIS156

site_id	AJ3
Number of Residues	2
Details	binding site for residue SO4 P 302

Chain	Residue
P	HIS209
P	ARG213

site_id	AJ4
Number of Residues	3
Details	binding site for residue SO4 P 303

Chain	Residue
P	ASN194
P	GLU196
P	HOH402

site_id	AJ5
Number of Residues	10
Details	binding site for residue VFZ P 304

Chain	Residue
P	VAL132
P	ASN133
P	SER150
P	GLY151
P	MET169
P	SO4301
Q	ASP70
Q	LEU71
Q	HIS118
Q	ALA138

site_id	AJ6
Number of Residues	2
Details	binding site for residue CL Q 301

Chain	Residue
Q	HIS209
Q	ARG213

site_id	AJ7
Number of Residues	4
Details	binding site for residue SO4 Q 302

Chain	Residue
Q	GLY168
Q	MET169
Q	VFZ303
R	HIS156

site_id	AJ8
Number of Residues	8
Details	binding site for residue VFZ Q 303

Chain	Residue
Q	VAL132
Q	ASN133
Q	SER150
Q	GLY151
Q	MET169
Q	SO4302
R	ALA138
R	HIS156

site_id	AJ9
Number of Residues	5
Details	binding site for residue SO4 R 301

Chain	Residue
P	HIS156
R	GLY168
R	MET169
R	PHE184
R	VFZ304

site_id	AK1
Number of Residues	4
Details	binding site for residue SO4 R 302

Chain	Residue
P	TRP25
Q	TRP25
R	ARG7
R	TRP25

site_id	AK2
Number of Residues	4
Details	binding site for residue SO4 R 303

Chain	Residue
R	PHE166
R	THR182
R	ASN194
R	GLU196

site_id	AK3
Number of Residues	10
Details	binding site for residue VFZ R 304

Chain	Residue
P	HIS118
P	ALA138
P	HIS156
R	VAL132
R	ASN133
R	SER150
R	GLY151
R	PHE166
R	MET169
R	SO4301

site_id	AK4
Number of Residues	2
Details	binding site for residue CL S 301

Chain	Residue
S	LYS216
S	ARG220

site_id	AK5
Number of Residues	4
Details	binding site for residue SO4 S 302

Chain	Residue
S	GLY168
S	MET169
S	VFZ303
T	HIS156

site_id	AK6
Number of Residues	8
Details	binding site for residue VFZ S 303

Chain	Residue
S	VAL132
S	ASN133
S	SER150
S	GLY151
S	SO4302
T	HIS118
T	ALA138
T	HIS156

site_id	AK7
Number of Residues	2
Details	binding site for residue CL T 301

Chain	Residue
T	HIS209
T	ARG213

site_id	AK8
Number of Residues	5
Details	binding site for residue SO4 T 302

Chain	Residue
T	GLY168
T	MET169
T	PHE184
T	VFZ303
U	HIS156

site_id	AK9
Number of Residues	10
Details	binding site for residue VFZ T 303

Chain	Residue
T	VAL132
T	ASN133
T	SER150
T	GLY151
T	MET169
T	SO4302
U	LEU71
U	HIS118
U	ALA138
U	HIS156

site_id	AL1
Number of Residues	5
Details	binding site for residue SO4 U 301

Chain	Residue
S	HIS156
U	GLY168
U	MET169
U	PHE184
U	VFZ304

site_id	AL2
Number of Residues	6
Details	binding site for residue SO4 U 302

Chain	Residue
S	ARG7
S	TRP25
T	ARG7
T	TRP25
U	ARG7
U	TRP25

site_id	AL3
Number of Residues	2
Details	binding site for residue SO4 U 303

Chain	Residue
U	HIS209
U	ARG213

site_id	AL4
Number of Residues	10
Details	binding site for residue VFZ U 304

Chain	Residue
S	LEU71
S	HIS118
S	ALA138
U	MET114
U	VAL132
U	ASN133
U	SER150
U	GLY151
U	MET169
U	SO4301

site_id	AL5
Number of Residues	5
Details	binding site for residue SO4 V 301

Chain	Residue
V	GLY168
V	MET169
V	PHE184
V	VFZ303
W	HIS156

site_id	AL6
Number of Residues	5
Details	binding site for residue SO4 V 302

Chain	Residue
V	ARG7
V	TRP25
W	TRP25
X	ARG7
X	TRP25

site_id	AL7
Number of Residues	8
Details	binding site for residue VFZ V 303

Chain	Residue
V	MET114
V	VAL132
V	ASN133
V	SER150
V	GLY151
V	MET169
V	SO4301
W	ALA138

site_id	AL8
Number of Residues	5
Details	binding site for residue SO4 W 301

Chain	Residue
W	GLY168
W	MET169
W	PHE184
W	VFZ302
X	HIS156

site_id	AL9
Number of Residues	9
Details	binding site for residue VFZ W 302

Chain	Residue
W	VAL132
W	ASN133
W	SER150
W	GLY151
W	PHE166
W	MET169
W	SO4301
X	ALA138
X	HIS156

site_id	AM1
Number of Residues	2
Details	binding site for residue CL X 301

Chain	Residue
X	LYS216
X	ARG220

site_id	AM2
Number of Residues	2
Details	binding site for residue CL X 302

Chain	Residue
X	HIS209
X	ARG213

site_id	AM3
Number of Residues	4
Details	binding site for residue SO4 X 303

Chain	Residue
X	GLY168
X	MET169
X	PHE184
X	VFZ304

site_id	AM4
Number of Residues	9
Details	binding site for residue VFZ X 304

Chain	Residue
V	LEU71
V	HIS118
V	ALA138
V	HIS156
X	VAL132
X	ASN133
X	SER150
X	GLY151
X	SO4303

site_id	AM5
Number of Residues	5
Details	binding site for residue SO4 Y 301

Chain	Residue
Y	GLY168
Y	MET169
Y	PHE184
Y	VFZ303
Z	HIS156

site_id	AM6
Number of Residues	6
Details	binding site for residue SO4 Y 302

Chain	Residue
Y	ARG7
Y	TRP25
Z	ARG7
Z	TRP25
a	ARG7
a	TRP25

site_id	AM7
Number of Residues	9
Details	binding site for residue VFZ Y 303

Chain	Residue
Y	VAL132
Y	ASN133
Y	SER150
Y	GLY151
Y	MET169
Y	SO4301
Z	HIS118
Z	ALA138
Z	HIS156

site_id	AM8
Number of Residues	5
Details	binding site for residue SO4 Z 301

Chain	Residue
Z	GLY168
Z	MET169
Z	PHE184
Z	VFZ302
a	HIS156

site_id	AM9
Number of Residues	10
Details	binding site for residue VFZ Z 302

Chain	Residue
Z	MET114
Z	VAL132
Z	ASN133
Z	SER150
Z	GLY151
Z	MET169
Z	SO4301
a	ASP70
a	HIS118
a	ALA138

site_id	AN1
Number of Residues	5
Details	binding site for residue SO4 a 301

Chain	Residue
Y	HIS156
a	GLY168
a	MET169
a	PHE184
a	VFZ302

site_id	AN2
Number of Residues	9
Details	binding site for residue VFZ a 302

Chain	Residue
Y	LEU71
Y	ALA138
Y	HIS156
a	VAL132
a	ASN133
a	SER150
a	GLY151
a	MET169
a	SO4301

site_id	AN3
Number of Residues	5
Details	binding site for residue SO4 b 301

Chain	Residue
b	GLY168
b	MET169
b	PHE184
b	VFZ302
c	HIS156

site_id	AN4
Number of Residues	11
Details	binding site for residue VFZ b 302

Chain	Residue
b	MET114
b	VAL132
b	ASN133
b	SER150
b	GLY151
b	TYR152
b	PHE166
b	SO4301
c	ASP70
c	ALA138
c	HIS156

site_id	AN5
Number of Residues	4
Details	binding site for residue SO4 c 301

Chain	Residue
c	GLY168
c	MET169
c	PHE184
c	VFZ303

site_id	AN6
Number of Residues	6
Details	binding site for residue SO4 c 302

Chain	Residue
b	ARG7
b	TRP25
c	ARG7
c	TRP25
d	ARG7
d	TRP25

site_id	AN7
Number of Residues	11
Details	binding site for residue VFZ c 303

Chain	Residue
c	MET114
c	VAL132
c	ASN133
c	SER150
c	GLY151
c	PHE166
c	MET169
c	SO4301
d	LEU71
d	ALA138
d	HIS156

site_id	AN8
Number of Residues	5
Details	binding site for residue SO4 d 301

Chain	Residue
b	HIS156
d	GLY168
d	MET169
d	PHE184
d	VFZ302

site_id	AN9
Number of Residues	10
Details	binding site for residue VFZ d 302

Chain	Residue
b	LEU71
b	HIS118
b	ALA138
b	HIS156
d	VAL132
d	ASN133
d	SER150
d	GLY151
d	MET169
d	SO4301

Functional Information from PROSITE/UniProt

site_id	PS00101
Number of Residues	29
Details	HEXAPEP_TRANSFERASES Hexapeptide-repeat containing-transferases signature. IDprAiIdpsArLAadVqVGpwSiVgaeV

Chain	Residue	Details
A	ILE4-VAL32

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)