7OJY

Crystal structure of Pseudomonas aeruginosa LpxA in complex with compound 6

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0006629	biological_process	lipid metabolic process
A	0008610	biological_process	lipid biosynthetic process
A	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
A	0009245	biological_process	lipid A biosynthetic process
A	0016020	cellular_component	membrane
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
B	0005737	cellular_component	cytoplasm
B	0006629	biological_process	lipid metabolic process
B	0008610	biological_process	lipid biosynthetic process
B	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
B	0009245	biological_process	lipid A biosynthetic process
B	0016020	cellular_component	membrane
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
C	0005737	cellular_component	cytoplasm
C	0006629	biological_process	lipid metabolic process
C	0008610	biological_process	lipid biosynthetic process
C	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
C	0009245	biological_process	lipid A biosynthetic process
C	0016020	cellular_component	membrane
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue VGQ A 301

Chain	Residue
A	LEU112
A	VAL132
A	ASN133
A	SER150
A	GLY151
A	HOH523
B	HIS118
B	ALA138
B	GLN157

---

site_id	AC2
Number of Residues	2
Details	binding site for residue CL A 302

Chain	Residue
A	LYS54
C	HOH417

---

site_id	AC3
Number of Residues	2
Details	binding site for residue CL A 303

Chain	Residue
A	MET169
A	HOH465

---

site_id	AC4
Number of Residues	4
Details	binding site for residue CL A 304

Chain	Residue
A	ARG89
A	ALA115
A	HOH443
A	HOH561

---

site_id	AC5
Number of Residues	2
Details	binding site for residue CL A 305

Chain	Residue
A	ARG199
B	ARG199

---

site_id	AC6
Number of Residues	5
Details	binding site for residue CL A 306

Chain	Residue
A	PRO69
A	HIS95
A	GLY120
A	HIS121
A	HOH416

---

site_id	AC7
Number of Residues	1
Details	binding site for residue CL A 307

Chain	Residue
A	THR182

---

site_id	AC8
Number of Residues	9
Details	binding site for residue VGQ B 301

Chain	Residue
B	LEU112
B	VAL132
B	ASN133
B	SER150
B	GLY151
B	HOH495
C	HIS121
C	ALA138
C	GLN157

---

site_id	AC9
Number of Residues	4
Details	binding site for residue CL B 302

Chain	Residue
B	ARG89
B	ALA115
B	HOH409
B	HOH423

---

site_id	AD1
Number of Residues	5
Details	binding site for residue CL B 303

Chain	Residue
B	HIS95
B	GLY120
B	HIS121
B	HOH405
B	HOH560

---

site_id	AD2
Number of Residues	4
Details	binding site for residue CL B 304

Chain	Residue
B	ARG89
B	HOH525
C	GLU66
C	ASP67

---

site_id	AD3
Number of Residues	3
Details	binding site for residue CL B 305

Chain	Residue
B	GLY168
B	MET169
B	HOH425

---

site_id	AD4
Number of Residues	10
Details	binding site for residue VGQ C 301

Chain	Residue
A	HIS118
A	ALA138
A	GLN157
C	LEU112
C	VAL132
C	ASN133
C	SER150
C	GLY151
C	MET169
C	HOH499

---

site_id	AD5
Number of Residues	5
Details	binding site for residue CL C 302

Chain	Residue
C	PRO69
C	HIS95
C	HIS121
C	HOH418
C	HOH542

---

site_id	AD6
Number of Residues	4
Details	binding site for residue CL C 303

Chain	Residue
A	HOH449
C	GLY35
C	LYS54
C	HOH467

---

site_id	AD7
Number of Residues	3
Details	binding site for residue CL C 304

Chain	Residue
C	ARG89
C	ALA115
C	HOH447

---

site_id	AD8
Number of Residues	3
Details	binding site for residue CL C 305

Chain	Residue
C	GLY168
C	MET169
C	HOH453

---

Functional Information from PROSITE/UniProt

site_id	PS00101
Number of Residues	29
Details	HEXAPEP_TRANSFERASES Hexapeptide-repeat containing-transferases signature. IDprAiIdpsArLAadVqVGpwSiVgaeV

Chain	Residue	Details
A	ILE4-VAL32

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