7OJW

Crystal structure of Pseudomonas aeruginosa LpxA in complex with compound 93

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0008610	biological_process	lipid biosynthetic process
A	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
A	0009103	biological_process	lipopolysaccharide biosynthetic process
A	0009245	biological_process	lipid A biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
B	0005737	cellular_component	cytoplasm
B	0008610	biological_process	lipid biosynthetic process
B	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
B	0009103	biological_process	lipopolysaccharide biosynthetic process
B	0009245	biological_process	lipid A biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
C	0005737	cellular_component	cytoplasm
C	0008610	biological_process	lipid biosynthetic process
C	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
C	0009103	biological_process	lipopolysaccharide biosynthetic process
C	0009245	biological_process	lipid A biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue VFW A 301

Chain	Residue
A	LEU112
B	ALA138
B	VAL155
B	GLN157
A	ILE130
A	VAL132
A	ASN133
A	SER150
A	GLY151
A	HOH419
A	HOH482
B	ALA136

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site_id	AC2
Number of Residues	13
Details	binding site for residue VFW B 301

Chain	Residue
B	LEU112
B	ILE130
B	VAL132
B	ASN133
B	SER150
B	GLY151
B	HOH417
B	HOH450
B	HOH465
C	ALA136
C	ALA138
C	VAL155
C	GLN157

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site_id	AC3
Number of Residues	10
Details	binding site for residue VFW C 301

Chain	Residue
A	ALA136
A	ALA138
A	GLN157
C	LEU112
C	ILE130
C	VAL132
C	ASN133
C	SER150
C	GLY151
C	HOH415

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Functional Information from PROSITE/UniProt

site_id	PS00101
Number of Residues	29
Details	HEXAPEP_TRANSFERASES Hexapeptide-repeat containing-transferases signature. IDprAiIdpsArLAadVqVGpwSiVgaeV

Chain	Residue	Details
A	ILE4-VAL32

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