7OJP

Crystal structure of Pseudomonas aeruginosa LpxA in complex with compound 1

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0005737	cellular_component	cytoplasm
a	0005829	cellular_component	cytosol
a	0006629	biological_process	lipid metabolic process
a	0008610	biological_process	lipid biosynthetic process
a	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
a	0009103	biological_process	lipopolysaccharide biosynthetic process
a	0009245	biological_process	lipid A biosynthetic process
a	0016020	cellular_component	membrane
a	0016740	molecular_function	transferase activity
a	0016746	molecular_function	acyltransferase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006629	biological_process	lipid metabolic process
A	0008610	biological_process	lipid biosynthetic process
A	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
A	0009103	biological_process	lipopolysaccharide biosynthetic process
A	0009245	biological_process	lipid A biosynthetic process
A	0016020	cellular_component	membrane
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0006629	biological_process	lipid metabolic process
b	0008610	biological_process	lipid biosynthetic process
b	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
b	0009103	biological_process	lipopolysaccharide biosynthetic process
b	0009245	biological_process	lipid A biosynthetic process
b	0016020	cellular_component	membrane
b	0016740	molecular_function	transferase activity
b	0016746	molecular_function	acyltransferase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006629	biological_process	lipid metabolic process
B	0008610	biological_process	lipid biosynthetic process
B	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
B	0009103	biological_process	lipopolysaccharide biosynthetic process
B	0009245	biological_process	lipid A biosynthetic process
B	0016020	cellular_component	membrane
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
c	0005737	cellular_component	cytoplasm
c	0005829	cellular_component	cytosol
c	0006629	biological_process	lipid metabolic process
c	0008610	biological_process	lipid biosynthetic process
c	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
c	0009103	biological_process	lipopolysaccharide biosynthetic process
c	0009245	biological_process	lipid A biosynthetic process
c	0016020	cellular_component	membrane
c	0016740	molecular_function	transferase activity
c	0016746	molecular_function	acyltransferase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006629	biological_process	lipid metabolic process
C	0008610	biological_process	lipid biosynthetic process
C	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
C	0009103	biological_process	lipopolysaccharide biosynthetic process
C	0009245	biological_process	lipid A biosynthetic process
C	0016020	cellular_component	membrane
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
d	0005737	cellular_component	cytoplasm
d	0005829	cellular_component	cytosol
d	0006629	biological_process	lipid metabolic process
d	0008610	biological_process	lipid biosynthetic process
d	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
d	0009103	biological_process	lipopolysaccharide biosynthetic process
d	0009245	biological_process	lipid A biosynthetic process
d	0016020	cellular_component	membrane
d	0016740	molecular_function	transferase activity
d	0016746	molecular_function	acyltransferase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006629	biological_process	lipid metabolic process
D	0008610	biological_process	lipid biosynthetic process
D	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
D	0009103	biological_process	lipopolysaccharide biosynthetic process
D	0009245	biological_process	lipid A biosynthetic process
D	0016020	cellular_component	membrane
D	0016740	molecular_function	transferase activity
D	0016746	molecular_function	acyltransferase activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006629	biological_process	lipid metabolic process
E	0008610	biological_process	lipid biosynthetic process
E	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
E	0009103	biological_process	lipopolysaccharide biosynthetic process
E	0009245	biological_process	lipid A biosynthetic process
E	0016020	cellular_component	membrane
E	0016740	molecular_function	transferase activity
E	0016746	molecular_function	acyltransferase activity
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006629	biological_process	lipid metabolic process
F	0008610	biological_process	lipid biosynthetic process
F	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
F	0009103	biological_process	lipopolysaccharide biosynthetic process
F	0009245	biological_process	lipid A biosynthetic process
F	0016020	cellular_component	membrane
F	0016740	molecular_function	transferase activity
F	0016746	molecular_function	acyltransferase activity
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006629	biological_process	lipid metabolic process
G	0008610	biological_process	lipid biosynthetic process
G	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
G	0009103	biological_process	lipopolysaccharide biosynthetic process
G	0009245	biological_process	lipid A biosynthetic process
G	0016020	cellular_component	membrane
G	0016740	molecular_function	transferase activity
G	0016746	molecular_function	acyltransferase activity
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006629	biological_process	lipid metabolic process
H	0008610	biological_process	lipid biosynthetic process
H	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
H	0009103	biological_process	lipopolysaccharide biosynthetic process
H	0009245	biological_process	lipid A biosynthetic process
H	0016020	cellular_component	membrane
H	0016740	molecular_function	transferase activity
H	0016746	molecular_function	acyltransferase activity
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0006629	biological_process	lipid metabolic process
I	0008610	biological_process	lipid biosynthetic process
I	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
I	0009103	biological_process	lipopolysaccharide biosynthetic process
I	0009245	biological_process	lipid A biosynthetic process
I	0016020	cellular_component	membrane
I	0016740	molecular_function	transferase activity
I	0016746	molecular_function	acyltransferase activity
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006629	biological_process	lipid metabolic process
J	0008610	biological_process	lipid biosynthetic process
J	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
J	0009103	biological_process	lipopolysaccharide biosynthetic process
J	0009245	biological_process	lipid A biosynthetic process
J	0016020	cellular_component	membrane
J	0016740	molecular_function	transferase activity
J	0016746	molecular_function	acyltransferase activity
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0006629	biological_process	lipid metabolic process
K	0008610	biological_process	lipid biosynthetic process
K	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
K	0009103	biological_process	lipopolysaccharide biosynthetic process
K	0009245	biological_process	lipid A biosynthetic process
K	0016020	cellular_component	membrane
K	0016740	molecular_function	transferase activity
K	0016746	molecular_function	acyltransferase activity
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0006629	biological_process	lipid metabolic process
L	0008610	biological_process	lipid biosynthetic process
L	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
L	0009103	biological_process	lipopolysaccharide biosynthetic process
L	0009245	biological_process	lipid A biosynthetic process
L	0016020	cellular_component	membrane
L	0016740	molecular_function	transferase activity
L	0016746	molecular_function	acyltransferase activity
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0006629	biological_process	lipid metabolic process
M	0008610	biological_process	lipid biosynthetic process
M	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
M	0009103	biological_process	lipopolysaccharide biosynthetic process
M	0009245	biological_process	lipid A biosynthetic process
M	0016020	cellular_component	membrane
M	0016740	molecular_function	transferase activity
M	0016746	molecular_function	acyltransferase activity
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0006629	biological_process	lipid metabolic process
N	0008610	biological_process	lipid biosynthetic process
N	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
N	0009103	biological_process	lipopolysaccharide biosynthetic process
N	0009245	biological_process	lipid A biosynthetic process
N	0016020	cellular_component	membrane
N	0016740	molecular_function	transferase activity
N	0016746	molecular_function	acyltransferase activity
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0006629	biological_process	lipid metabolic process
O	0008610	biological_process	lipid biosynthetic process
O	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
O	0009103	biological_process	lipopolysaccharide biosynthetic process
O	0009245	biological_process	lipid A biosynthetic process
O	0016020	cellular_component	membrane
O	0016740	molecular_function	transferase activity
O	0016746	molecular_function	acyltransferase activity
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0006629	biological_process	lipid metabolic process
P	0008610	biological_process	lipid biosynthetic process
P	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
P	0009103	biological_process	lipopolysaccharide biosynthetic process
P	0009245	biological_process	lipid A biosynthetic process
P	0016020	cellular_component	membrane
P	0016740	molecular_function	transferase activity
P	0016746	molecular_function	acyltransferase activity
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0006629	biological_process	lipid metabolic process
Q	0008610	biological_process	lipid biosynthetic process
Q	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
Q	0009103	biological_process	lipopolysaccharide biosynthetic process
Q	0009245	biological_process	lipid A biosynthetic process
Q	0016020	cellular_component	membrane
Q	0016740	molecular_function	transferase activity
Q	0016746	molecular_function	acyltransferase activity
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0006629	biological_process	lipid metabolic process
R	0008610	biological_process	lipid biosynthetic process
R	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
R	0009103	biological_process	lipopolysaccharide biosynthetic process
R	0009245	biological_process	lipid A biosynthetic process
R	0016020	cellular_component	membrane
R	0016740	molecular_function	transferase activity
R	0016746	molecular_function	acyltransferase activity
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0006629	biological_process	lipid metabolic process
S	0008610	biological_process	lipid biosynthetic process
S	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
S	0009103	biological_process	lipopolysaccharide biosynthetic process
S	0009245	biological_process	lipid A biosynthetic process
S	0016020	cellular_component	membrane
S	0016740	molecular_function	transferase activity
S	0016746	molecular_function	acyltransferase activity
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0006629	biological_process	lipid metabolic process
T	0008610	biological_process	lipid biosynthetic process
T	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
T	0009103	biological_process	lipopolysaccharide biosynthetic process
T	0009245	biological_process	lipid A biosynthetic process
T	0016020	cellular_component	membrane
T	0016740	molecular_function	transferase activity
T	0016746	molecular_function	acyltransferase activity
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0006629	biological_process	lipid metabolic process
U	0008610	biological_process	lipid biosynthetic process
U	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
U	0009103	biological_process	lipopolysaccharide biosynthetic process
U	0009245	biological_process	lipid A biosynthetic process
U	0016020	cellular_component	membrane
U	0016740	molecular_function	transferase activity
U	0016746	molecular_function	acyltransferase activity
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0006629	biological_process	lipid metabolic process
V	0008610	biological_process	lipid biosynthetic process
V	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
V	0009103	biological_process	lipopolysaccharide biosynthetic process
V	0009245	biological_process	lipid A biosynthetic process
V	0016020	cellular_component	membrane
V	0016740	molecular_function	transferase activity
V	0016746	molecular_function	acyltransferase activity
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0006629	biological_process	lipid metabolic process
W	0008610	biological_process	lipid biosynthetic process
W	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
W	0009103	biological_process	lipopolysaccharide biosynthetic process
W	0009245	biological_process	lipid A biosynthetic process
W	0016020	cellular_component	membrane
W	0016740	molecular_function	transferase activity
W	0016746	molecular_function	acyltransferase activity
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0006629	biological_process	lipid metabolic process
X	0008610	biological_process	lipid biosynthetic process
X	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
X	0009103	biological_process	lipopolysaccharide biosynthetic process
X	0009245	biological_process	lipid A biosynthetic process
X	0016020	cellular_component	membrane
X	0016740	molecular_function	transferase activity
X	0016746	molecular_function	acyltransferase activity
Y	0005737	cellular_component	cytoplasm
Y	0005829	cellular_component	cytosol
Y	0006629	biological_process	lipid metabolic process
Y	0008610	biological_process	lipid biosynthetic process
Y	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
Y	0009103	biological_process	lipopolysaccharide biosynthetic process
Y	0009245	biological_process	lipid A biosynthetic process
Y	0016020	cellular_component	membrane
Y	0016740	molecular_function	transferase activity
Y	0016746	molecular_function	acyltransferase activity
Z	0005737	cellular_component	cytoplasm
Z	0005829	cellular_component	cytosol
Z	0006629	biological_process	lipid metabolic process
Z	0008610	biological_process	lipid biosynthetic process
Z	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
Z	0009103	biological_process	lipopolysaccharide biosynthetic process
Z	0009245	biological_process	lipid A biosynthetic process
Z	0016020	cellular_component	membrane
Z	0016740	molecular_function	transferase activity
Z	0016746	molecular_function	acyltransferase activity

Functional Information from PROSITE/UniProt

site_id	PS00101
Number of Residues	29
Details	HEXAPEP_TRANSFERASES Hexapeptide-repeat containing-transferases signature. IDprAiIdpsArLAadVqVGpwSiVgaeV

Chain	Residue	Details
A	ILE4-VAL32

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