7OGM

A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation. PNPase-3'ETS(leuZ)-Hfq

Functional Information from GO Data

Chain	GOid	namespace	contents
D	0000049	molecular_function	tRNA binding
D	0003677	molecular_function	DNA binding
D	0003681	molecular_function	bent DNA binding
D	0003723	molecular_function	RNA binding
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006355	biological_process	regulation of DNA-templated transcription
D	0008033	biological_process	tRNA processing
D	0034337	biological_process	RNA folding
D	0040033	biological_process	sRNA-mediated post-transcriptional gene silencing
D	0043487	biological_process	regulation of RNA stability
D	0043590	cellular_component	bacterial nucleoid
D	0045974	biological_process	regulation of translation, ncRNA-mediated
D	0045975	biological_process	positive regulation of translation, ncRNA-mediated
D	0140691	molecular_function	RNA folding chaperone
E	0000049	molecular_function	tRNA binding
E	0003677	molecular_function	DNA binding
E	0003681	molecular_function	bent DNA binding
E	0003723	molecular_function	RNA binding
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006355	biological_process	regulation of DNA-templated transcription
E	0008033	biological_process	tRNA processing
E	0034337	biological_process	RNA folding
E	0040033	biological_process	sRNA-mediated post-transcriptional gene silencing
E	0043487	biological_process	regulation of RNA stability
E	0043590	cellular_component	bacterial nucleoid
E	0045974	biological_process	regulation of translation, ncRNA-mediated
E	0045975	biological_process	positive regulation of translation, ncRNA-mediated
E	0140691	molecular_function	RNA folding chaperone
F	0000049	molecular_function	tRNA binding
F	0003677	molecular_function	DNA binding
F	0003681	molecular_function	bent DNA binding
F	0003723	molecular_function	RNA binding
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006355	biological_process	regulation of DNA-templated transcription
F	0008033	biological_process	tRNA processing
F	0034337	biological_process	RNA folding
F	0040033	biological_process	sRNA-mediated post-transcriptional gene silencing
F	0043487	biological_process	regulation of RNA stability
F	0043590	cellular_component	bacterial nucleoid
F	0045974	biological_process	regulation of translation, ncRNA-mediated
F	0045975	biological_process	positive regulation of translation, ncRNA-mediated
F	0140691	molecular_function	RNA folding chaperone
I	0000049	molecular_function	tRNA binding
I	0003677	molecular_function	DNA binding
I	0003681	molecular_function	bent DNA binding
I	0003723	molecular_function	RNA binding
I	0005515	molecular_function	protein binding
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0006355	biological_process	regulation of DNA-templated transcription
I	0008033	biological_process	tRNA processing
I	0034337	biological_process	RNA folding
I	0040033	biological_process	sRNA-mediated post-transcriptional gene silencing
I	0043487	biological_process	regulation of RNA stability
I	0043590	cellular_component	bacterial nucleoid
I	0045974	biological_process	regulation of translation, ncRNA-mediated
I	0045975	biological_process	positive regulation of translation, ncRNA-mediated
I	0140691	molecular_function	RNA folding chaperone
J	0000049	molecular_function	tRNA binding
J	0003677	molecular_function	DNA binding
J	0003681	molecular_function	bent DNA binding
J	0003723	molecular_function	RNA binding
J	0005515	molecular_function	protein binding
J	0005524	molecular_function	ATP binding
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006355	biological_process	regulation of DNA-templated transcription
J	0008033	biological_process	tRNA processing
J	0034337	biological_process	RNA folding
J	0040033	biological_process	sRNA-mediated post-transcriptional gene silencing
J	0043487	biological_process	regulation of RNA stability
J	0043590	cellular_component	bacterial nucleoid
J	0045974	biological_process	regulation of translation, ncRNA-mediated
J	0045975	biological_process	positive regulation of translation, ncRNA-mediated
J	0140691	molecular_function	RNA folding chaperone
K	0000049	molecular_function	tRNA binding
K	0003677	molecular_function	DNA binding
K	0003681	molecular_function	bent DNA binding
K	0003723	molecular_function	RNA binding
K	0005515	molecular_function	protein binding
K	0005524	molecular_function	ATP binding
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0006355	biological_process	regulation of DNA-templated transcription
K	0008033	biological_process	tRNA processing
K	0034337	biological_process	RNA folding
K	0040033	biological_process	sRNA-mediated post-transcriptional gene silencing
K	0043487	biological_process	regulation of RNA stability
K	0043590	cellular_component	bacterial nucleoid
K	0045974	biological_process	regulation of translation, ncRNA-mediated
K	0045975	biological_process	positive regulation of translation, ncRNA-mediated
K	0140691	molecular_function	RNA folding chaperone
L	0000175	molecular_function	3'-5'-RNA exonuclease activity
L	0000287	molecular_function	magnesium ion binding
L	0003676	molecular_function	nucleic acid binding
L	0003723	molecular_function	RNA binding
L	0004654	molecular_function	polyribonucleotide nucleotidyltransferase activity
L	0005515	molecular_function	protein binding
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0006396	biological_process	RNA processing
L	0006401	biological_process	RNA catabolic process
L	0006402	biological_process	mRNA catabolic process
L	0009408	biological_process	response to heat
L	0016020	cellular_component	membrane
L	0016740	molecular_function	transferase activity
L	0016779	molecular_function	nucleotidyltransferase activity
L	0035438	molecular_function	cyclic-di-GMP binding
L	0042802	molecular_function	identical protein binding
L	0046872	molecular_function	metal ion binding
N	0000175	molecular_function	3'-5'-RNA exonuclease activity
N	0000287	molecular_function	magnesium ion binding
N	0003676	molecular_function	nucleic acid binding
N	0003723	molecular_function	RNA binding
N	0004654	molecular_function	polyribonucleotide nucleotidyltransferase activity
N	0005515	molecular_function	protein binding
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0006396	biological_process	RNA processing
N	0006401	biological_process	RNA catabolic process
N	0006402	biological_process	mRNA catabolic process
N	0009408	biological_process	response to heat
N	0016020	cellular_component	membrane
N	0016740	molecular_function	transferase activity
N	0016779	molecular_function	nucleotidyltransferase activity
N	0035438	molecular_function	cyclic-di-GMP binding
N	0042802	molecular_function	identical protein binding
N	0046872	molecular_function	metal ion binding
O	0000175	molecular_function	3'-5'-RNA exonuclease activity
O	0000287	molecular_function	magnesium ion binding
O	0003676	molecular_function	nucleic acid binding
O	0003723	molecular_function	RNA binding
O	0004654	molecular_function	polyribonucleotide nucleotidyltransferase activity
O	0005515	molecular_function	protein binding
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0006396	biological_process	RNA processing
O	0006401	biological_process	RNA catabolic process
O	0006402	biological_process	mRNA catabolic process
O	0009408	biological_process	response to heat
O	0016020	cellular_component	membrane
O	0016740	molecular_function	transferase activity
O	0016779	molecular_function	nucleotidyltransferase activity
O	0035438	molecular_function	cyclic-di-GMP binding
O	0042802	molecular_function	identical protein binding
O	0046872	molecular_function	metal ion binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	354
Details	Domain: {"description":"Sm","evidences":[{"source":"PROSITE-ProRule","id":"PRU01346","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	177
Details	Domain: {"description":"KH","evidences":[{"source":"HAMAP-Rule","id":"MF_01595","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	136
Details	Domain: {"description":"S1 motif","evidences":[{"source":"HAMAP-Rule","id":"MF_01595","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	9
Details	Region: {"description":"FFRR loop; important for RNA binding","evidences":[{"source":"PubMed","id":"19327365","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	12
Details	Region: {"description":"Interaction with RNase E","evidences":[{"source":"PubMed","id":"19327365","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19327365","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---