7OFP
Apo Structure of Mu2 Adaptin Subunit (Ap50) Of AP2 Clathrin Adaptor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006886 | biological_process | intracellular protein transport |
| A | 0016192 | biological_process | vesicle-mediated transport |
| A | 0030131 | cellular_component | clathrin adaptor complex |
| B | 0006886 | biological_process | intracellular protein transport |
| B | 0016192 | biological_process | vesicle-mediated transport |
| B | 0030131 | cellular_component | clathrin adaptor complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 501 |
| Chain | Residue |
| A | THR326 |
| A | TRP381 |
| B | SER314 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 502 |
| Chain | Residue |
| A | PRO385 |
| A | SER387 |
| A | HOH601 |
| B | SER314 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 503 |
| Chain | Residue |
| A | ILE283 |
| A | VAL191 |
| A | THR280 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 504 |
| Chain | Residue |
| A | PHE311 |
| A | LYS312 |
| A | PHE394 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 505 |
| Chain | Residue |
| A | LYS339 |
| A | ALA359 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 506 |
| Chain | Residue |
| A | LYS213 |
| A | LYS405 |
| A | PHE407 |
| A | HOH602 |
| A | HOH605 |
| A | HOH614 |
| A | HOH627 |
| B | LYS405 |
| B | HOH611 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue CIT A 507 |
| Chain | Residue |
| A | LYS345 |
| A | GLU348 |
| A | HOH607 |
| A | HOH622 |
| B | LYS339 |
| B | ARG357 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 501 |
| Chain | Residue |
| B | ILE284 |
| B | PHE311 |
| B | LYS312 |
| B | PHE394 |
| B | LYS400 |
| B | HOH613 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | binding site for residue GOL B 502 |
| Chain | Residue |
| B | ARG170 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 503 |
| Chain | Residue |
| A | ARG423 |
| B | ASN182 |
| B | LEU183 |
| B | SER193 |
| B | ALA194 |
| B | HIS195 |
| B | ILE430 |
| B | HOH616 |
| B | HOH620 |
Functional Information from PROSITE/UniProt
| site_id | PS00990 |
| Number of Residues | 21 |
| Details | CLAT_ADAPTOR_M_1 Clathrin adaptor complexes medium chain signature 1. IGWRre.GikYrrNeLFLDVLE |
| Chain | Residue | Details |
| A | ILE159-GLU179 |
| site_id | PS00991 |
| Number of Residues | 15 |
| Details | CLAT_ADAPTOR_M_2 Clathrin adaptor complexes medium chain signature 2. IsFIPPdGeFeLmrY |
| Chain | Residue | Details |
| A | ILE263-TYR277 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12086608","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"25061211","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2VGL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4UQI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
