7OE9
C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH rac-N5-((1R,5S)-3-oxabicyclo[3.1.0]hexan-6-yl)-N7,3-dimethyl-3-phenyl-2,3-dihydrobenzofuran-5,7-dicarboxamide
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue V9N A 501 |
| Chain | Residue |
| A | LYS351 |
| A | HOH644 |
| A | HOH688 |
| A | TRP370 |
| A | PRO371 |
| A | LEU383 |
| A | TYR428 |
| A | ASN429 |
| A | PRO430 |
| A | MET438 |
| A | HOH621 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | TYR426 |
| A | ARG440 |
| A | GLN443 |
| A | GLN443 |
| A | ASP444 |
| A | HOH601 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | LYS402 |
| A | ASP407 |
| A | MET438 |
| A | LYS441 |
| A | HOH602 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. AwpFykpvDasalglhDYHdiIkhpMdlstVkrkmenrd..Yrdaqefaadvrl.MfsNCykY |
| Chain | Residue | Details |
| A | ALA369-TYR428 | |
