7ODE

E. coli 50S ribosome LiCl core particle

Functional Information from GO Data

Chain	GOid	namespace	contents
K	0000027	biological_process	ribosomal large subunit assembly
K	0002181	biological_process	cytoplasmic translation
K	0003723	molecular_function	RNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005515	molecular_function	protein binding
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0008270	molecular_function	zinc ion binding
K	0015934	cellular_component	large ribosomal subunit
K	0016740	molecular_function	transferase activity
K	0019843	molecular_function	rRNA binding
K	0022625	cellular_component	cytosolic large ribosomal subunit
K	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
K	1990082	cellular_component	DnaA-L2 complex
K	1990904	cellular_component	ribonucleoprotein complex
L	0000027	biological_process	ribosomal large subunit assembly
L	0002181	biological_process	cytoplasmic translation
L	0003723	molecular_function	RNA binding
L	0003735	molecular_function	structural constituent of ribosome
L	0005515	molecular_function	protein binding
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0019843	molecular_function	rRNA binding
L	0022625	cellular_component	cytosolic large ribosomal subunit
L	1990904	cellular_component	ribonucleoprotein complex
M	0001070	molecular_function	RNA-binding transcription regulator activity
M	0002181	biological_process	cytoplasmic translation
M	0003677	molecular_function	DNA binding
M	0003723	molecular_function	RNA binding
M	0003735	molecular_function	structural constituent of ribosome
M	0005515	molecular_function	protein binding
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0005840	cellular_component	ribosome
M	0006353	biological_process	DNA-templated transcription termination
M	0006412	biological_process	translation
M	0006417	biological_process	regulation of translation
M	0015934	cellular_component	large ribosomal subunit
M	0017148	biological_process	negative regulation of translation
M	0019843	molecular_function	rRNA binding
M	0022625	cellular_component	cytosolic large ribosomal subunit
M	0030371	molecular_function	translation repressor activity
M	0031555	biological_process	transcriptional attenuation
M	0042255	biological_process	ribosome assembly
M	0045892	biological_process	negative regulation of DNA-templated transcription
M	0046677	biological_process	response to antibiotic
M	0048027	molecular_function	mRNA 5'-UTR binding
M	0060698	molecular_function	endoribonuclease inhibitor activity
M	1990904	cellular_component	ribonucleoprotein complex
M	2000766	biological_process	negative regulation of cytoplasmic translation
R	0002181	biological_process	cytoplasmic translation
R	0003729	molecular_function	mRNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	0008270	molecular_function	zinc ion binding
R	0017148	biological_process	negative regulation of translation
R	0022625	cellular_component	cytosolic large ribosomal subunit
R	0048027	molecular_function	mRNA 5'-UTR binding
R	0070180	molecular_function	large ribosomal subunit rRNA binding
R	1990904	cellular_component	ribonucleoprotein complex
S	0002181	biological_process	cytoplasmic translation
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005515	molecular_function	protein binding
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0015934	cellular_component	large ribosomal subunit
S	0019843	molecular_function	rRNA binding
S	0022625	cellular_component	cytosolic large ribosomal subunit
S	0070180	molecular_function	large ribosomal subunit rRNA binding
S	1990904	cellular_component	ribonucleoprotein complex
V	0000027	biological_process	ribosomal large subunit assembly
V	0002181	biological_process	cytoplasmic translation
V	0003735	molecular_function	structural constituent of ribosome
V	0005515	molecular_function	protein binding
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0022625	cellular_component	cytosolic large ribosomal subunit
V	1990904	cellular_component	ribonucleoprotein complex
X	0000027	biological_process	ribosomal large subunit assembly
X	0002181	biological_process	cytoplasmic translation
X	0003723	molecular_function	RNA binding
X	0003735	molecular_function	structural constituent of ribosome
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	0019843	molecular_function	rRNA binding
X	0022625	cellular_component	cytosolic large ribosomal subunit
X	0070180	molecular_function	large ribosomal subunit rRNA binding
X	1990904	cellular_component	ribonucleoprotein complex
Y	0000027	biological_process	ribosomal large subunit assembly
Y	0000900	molecular_function	mRNA regulatory element binding translation repressor activity
Y	0002181	biological_process	cytoplasmic translation
Y	0003723	molecular_function	RNA binding
Y	0003729	molecular_function	mRNA binding
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005737	cellular_component	cytoplasm
Y	0005829	cellular_component	cytosol
Y	0005840	cellular_component	ribosome
Y	0006412	biological_process	translation
Y	0017148	biological_process	negative regulation of translation
Y	0019843	molecular_function	rRNA binding
Y	0022625	cellular_component	cytosolic large ribosomal subunit
Y	0070180	molecular_function	large ribosomal subunit rRNA binding
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0002181	biological_process	cytoplasmic translation
Z	0003723	molecular_function	RNA binding
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005737	cellular_component	cytoplasm
Z	0005829	cellular_component	cytosol
Z	0005840	cellular_component	ribosome
Z	0006412	biological_process	translation
Z	0019843	molecular_function	rRNA binding
Z	0022625	cellular_component	cytosolic large ribosomal subunit
Z	1990904	cellular_component	ribonucleoprotein complex
a	0002181	biological_process	cytoplasmic translation
a	0003723	molecular_function	RNA binding
a	0003735	molecular_function	structural constituent of ribosome
a	0005515	molecular_function	protein binding
a	0005737	cellular_component	cytoplasm
a	0005829	cellular_component	cytosol
a	0005840	cellular_component	ribosome
a	0006412	biological_process	translation
a	0015934	cellular_component	large ribosomal subunit
a	0019843	molecular_function	rRNA binding
a	0022625	cellular_component	cytosolic large ribosomal subunit
a	0042255	biological_process	ribosome assembly
a	0042256	biological_process	cytosolic ribosome assembly
a	0046677	biological_process	response to antibiotic
a	0070180	molecular_function	large ribosomal subunit rRNA binding
a	1902626	biological_process	assembly of large subunit precursor of preribosome
a	1990904	cellular_component	ribonucleoprotein complex
b	0000027	biological_process	ribosomal large subunit assembly
b	0002181	biological_process	cytoplasmic translation
b	0003723	molecular_function	RNA binding
b	0003735	molecular_function	structural constituent of ribosome
b	0005515	molecular_function	protein binding
b	0005737	cellular_component	cytoplasm
b	0005840	cellular_component	ribosome
b	0006412	biological_process	translation
b	0019843	molecular_function	rRNA binding
b	0022625	cellular_component	cytosolic large ribosomal subunit
b	1990904	cellular_component	ribonucleoprotein complex
c	0000027	biological_process	ribosomal large subunit assembly
c	0002181	biological_process	cytoplasmic translation
c	0003723	molecular_function	RNA binding
c	0003735	molecular_function	structural constituent of ribosome
c	0005515	molecular_function	protein binding
c	0005737	cellular_component	cytoplasm
c	0005829	cellular_component	cytosol
c	0005840	cellular_component	ribosome
c	0006412	biological_process	translation
c	0019843	molecular_function	rRNA binding
c	0022625	cellular_component	cytosolic large ribosomal subunit
c	0070180	molecular_function	large ribosomal subunit rRNA binding
c	1990904	cellular_component	ribonucleoprotein complex
g	0000027	biological_process	ribosomal large subunit assembly
g	0002181	biological_process	cytoplasmic translation
g	0003723	molecular_function	RNA binding
g	0003735	molecular_function	structural constituent of ribosome
g	0005737	cellular_component	cytoplasm
g	0005840	cellular_component	ribosome
g	0006412	biological_process	translation
g	0019843	molecular_function	rRNA binding
g	0022625	cellular_component	cytosolic large ribosomal subunit
g	1990904	cellular_component	ribonucleoprotein complex
i	0000027	biological_process	ribosomal large subunit assembly
i	0000302	biological_process	response to reactive oxygen species
i	0002181	biological_process	cytoplasmic translation
i	0003735	molecular_function	structural constituent of ribosome
i	0005515	molecular_function	protein binding
i	0005737	cellular_component	cytoplasm
i	0005829	cellular_component	cytosol
i	0005840	cellular_component	ribosome
i	0006412	biological_process	translation
i	0009314	biological_process	response to radiation
i	0015934	cellular_component	large ribosomal subunit
i	0022625	cellular_component	cytosolic large ribosomal subunit
i	1990904	cellular_component	ribonucleoprotein complex
k	0002181	biological_process	cytoplasmic translation
k	0003735	molecular_function	structural constituent of ribosome
k	0005515	molecular_function	protein binding
k	0005737	cellular_component	cytoplasm
k	0005840	cellular_component	ribosome
k	0006412	biological_process	translation
k	0022625	cellular_component	cytosolic large ribosomal subunit
k	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVVrtkkgvrrp.DGsvirFdgNacVL

Chain	Residue	Details
S	ALA60-LEU86

---

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVTLKegqnldfV

Chain	Residue	Details
b	LYS81-VAL96

---

site_id	PS00430
Number of Residues	66
Details	TONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. mireerllkvlraphvsekastameksntivlkvakdatkaeikaavqklfevevevv.........................................................NTLVVKGK

Chain	Residue	Details
b	MET1-LYS66

---

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. KriMpRAkGRadrilkrtSHITVvV

Chain	Residue	Details
a	LYS83-VAL107

---

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PtvRGTAmNPvD

Chain	Residue	Details
K	PRO218-ASP229

---

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FadvkkvDvtGtSkGKGfaGtvkR

Chain	Residue	Details
L	PHE101-ARG124

---

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. QSHLLKqVRRDVARV

Chain	Residue	Details
g	GLN39-VAL53

---

site_id	PS00783
Number of Residues	23
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. VKGMLPkgpl.GRamfrkLkVYaG

Chain	Residue	Details
R	VAL105-GLY127

---

site_id	PS00784
Number of Residues	20
Details	RIBOSOMAL_L34 Ribosomal protein L34 signature. KRTFQpsvlkRnrsh.GFraR

Chain	Residue	Details
k	LYS2-ARG21

---

site_id	PS00937
Number of Residues	17
Details	RIBOSOMAL_L20 Ribosomal protein L20 signature. KrqfRqLWIARINaaaR

Chain	Residue	Details
Y	LYS54-ARG70

---

site_id	PS01015
Number of Residues	16
Details	RIBOSOMAL_L19 Ribosomal protein L19 signature. VkRrGAVR.KAKLYYLR

Chain	Residue	Details
X	VAL86-ARG101

---

site_id	PS01108
Number of Residues	18
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeViVLtGkdKGkr.GkV

Chain	Residue	Details
c	ASP8-VAL25

---

site_id	PS01167
Number of Residues	23
Details	RIBOSOMAL_L17 Ribosomal protein L17 signature. IkTTlpKaKelrrvvEpLITlAK

Chain	Residue	Details
V	ILE34-LYS56

---

site_id	PS01169
Number of Residues	23
Details	RIBOSOMAL_L21 Ribosomal protein L21 signature. VkivKfrrRKhyrkqqGHRQwfT

Chain	Residue	Details
Z	VAL72-THR94

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	25
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	9
Details	Compositional bias: {"description":"Low complexity","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"PubMed","id":"21151122","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"34403461","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34504068","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7O19","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7O1A","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7O1C","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7OIZ","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7OJ0","evidenceCode":"ECO:0000312"}]}

Chain

Residue

Details

---