Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004013 | molecular_function | adenosylhomocysteinase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006730 | biological_process | one-carbon metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0033353 | biological_process | S-adenosylmethionine cycle |
| A | 0071269 | biological_process | L-homocysteine biosynthetic process |
| C | 0004013 | molecular_function | adenosylhomocysteinase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006730 | biological_process | one-carbon metabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0033353 | biological_process | S-adenosylmethionine cycle |
| C | 0071269 | biological_process | L-homocysteine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue 1PE A 501 |
| Chain | Residue |
| A | ILE51 |
| A | ASN127 |
| A | SER149 |
| A | SER149 |
| A | ASP150 |
| A | ILE152 |
| A | ILE152 |
| A | LYS377 |
| A | LYS377 |
| site_id | AC2 |
| Number of Residues | 30 |
| Details | binding site for residue NAD A 502 |
| Chain | Residue |
| A | THR158 |
| A | THR159 |
| A | THR160 |
| A | ASN192 |
| A | THR196 |
| A | GLY221 |
| A | GLY223 |
| A | TRP224 |
| A | CYS225 |
| A | GLU244 |
| A | ILE245 |
| A | PRO249 |
| A | VAL276 |
| A | THR277 |
| A | GLY278 |
| A | ASN279 |
| A | SER300 |
| A | GLY301 |
| A | HIS302 |
| A | LEU345 |
| A | ASN347 |
| A | HIS354 |
| A | ADN503 |
| A | HOH613 |
| A | HOH654 |
| A | HOH676 |
| A | HOH703 |
| A | HOH722 |
| A | HOH743 |
| A | HOH769 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | binding site for residue ADN A 503 |
| Chain | Residue |
| A | HIS58 |
| A | THR60 |
| A | GLU62 |
| A | THR63 |
| A | ASP132 |
| A | GLU157 |
| A | THR158 |
| A | LYS187 |
| A | ASP191 |
| A | HIS302 |
| A | HIS354 |
| A | MET359 |
| A | PHE363 |
| A | NAD502 |
| A | HOH621 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 504 |
| Chain | Residue |
| A | ARG41 |
| A | HOH650 |
| A | HOH854 |
| site_id | AC5 |
| Number of Residues | 30 |
| Details | binding site for residue NAD C 501 |
| Chain | Residue |
| C | THR158 |
| C | THR159 |
| C | THR160 |
| C | ASN192 |
| C | THR196 |
| C | GLY221 |
| C | GLY223 |
| C | TRP224 |
| C | CYS225 |
| C | GLU244 |
| C | ILE245 |
| C | VAL276 |
| C | THR277 |
| C | GLY278 |
| C | ASN279 |
| C | VAL282 |
| C | SER300 |
| C | GLY301 |
| C | HIS302 |
| C | LEU345 |
| C | ASN347 |
| C | HIS354 |
| C | GLN414 |
| C | HOH611 |
| C | HOH623 |
| C | HOH663 |
| C | HOH671 |
| C | HOH678 |
| C | HOH690 |
| C | HOH697 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue CL C 502 |
Functional Information from PROSITE/UniProt
| site_id | PS00738 |
| Number of Residues | 15 |
| Details | ADOHCYASE_1 S-adenosyl-L-homocysteine hydrolase signature 1. ASNpLSTQDdVAACL |
| Chain | Residue | Details |
| A | ALA81-LEU95 | |
| site_id | PS00739 |
| Number of Residues | 17 |
| Details | ADOHCYASE_2 S-adenosyl-L-homocysteine hydrolase signature 2. GKtivVaGYGwCGKGv.A |
| Chain | Residue | Details |
| A | GLY214-ALA230 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 36 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00563","evidenceCode":"ECO:0000255"}]} |
