7O41

Hexameric composite model of the Inner Membrane Complex (IMC) with the Arches from the fully-assembled R388 type IV secretion system determined by cryo-EM.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
B	0000166	molecular_function	nucleotide binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
C	0005515	molecular_function	protein binding
C	0005886	cellular_component	plasma membrane
D	0005515	molecular_function	protein binding
D	0005886	cellular_component	plasma membrane
D	0016020	cellular_component	membrane
D	0030255	biological_process	protein secretion by the type IV secretion system
E	0005515	molecular_function	protein binding
E	0005886	cellular_component	plasma membrane
E	0016020	cellular_component	membrane
E	0030255	biological_process	protein secretion by the type IV secretion system
F	0005515	molecular_function	protein binding
F	0005886	cellular_component	plasma membrane
F	0016020	cellular_component	membrane
F	0030255	biological_process	protein secretion by the type IV secretion system

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	74
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"35732732","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	26
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"35732732","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7OIU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	44
Details	Transmembrane: {"evidences":[{"source":"PubMed","id":"35732732","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7OIU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	14
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	69
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"35732732","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---