7NYH

Respiratory complex I from Escherichia coli - focused refinement of membrane arm

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003954	molecular_function	NADH dehydrogenase activity
A	0005886	cellular_component	plasma membrane
A	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
A	0016020	cellular_component	membrane
A	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
A	0022904	biological_process	respiratory electron transport chain
A	0030964	cellular_component	NADH dehydrogenase complex
A	0045271	cellular_component	respiratory chain complex I
A	0048038	molecular_function	quinone binding
A	0050136	molecular_function	NADH dehydrogenase (quinone) (non-electrogenic) activity
A	1902600	biological_process	proton transmembrane transport
H	0003954	molecular_function	NADH dehydrogenase activity
H	0005886	cellular_component	plasma membrane
H	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
H	0009060	biological_process	aerobic respiration
H	0016020	cellular_component	membrane
H	0016655	molecular_function	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
H	0022904	biological_process	respiratory electron transport chain
H	0030964	cellular_component	NADH dehydrogenase complex
H	0045271	cellular_component	respiratory chain complex I
H	0048038	molecular_function	quinone binding
H	1902600	biological_process	proton transmembrane transport
J	0003954	molecular_function	NADH dehydrogenase activity
J	0005886	cellular_component	plasma membrane
J	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
J	0016020	cellular_component	membrane
J	0022904	biological_process	respiratory electron transport chain
J	0030964	cellular_component	NADH dehydrogenase complex
J	0045271	cellular_component	respiratory chain complex I
J	0048038	molecular_function	quinone binding
J	1902600	biological_process	proton transmembrane transport
K	0003954	molecular_function	NADH dehydrogenase activity
K	0005515	molecular_function	protein binding
K	0005886	cellular_component	plasma membrane
K	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
K	0016020	cellular_component	membrane
K	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
K	0022904	biological_process	respiratory electron transport chain
K	0030964	cellular_component	NADH dehydrogenase complex
K	0042773	biological_process	ATP synthesis coupled electron transport
K	0045271	cellular_component	respiratory chain complex I
K	0048038	molecular_function	quinone binding
K	0050136	molecular_function	NADH dehydrogenase (quinone) (non-electrogenic) activity
K	1902600	biological_process	proton transmembrane transport
L	0003954	molecular_function	NADH dehydrogenase activity
L	0005886	cellular_component	plasma membrane
L	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
L	0015990	biological_process	electron transport coupled proton transport
L	0016020	cellular_component	membrane
L	0022904	biological_process	respiratory electron transport chain
L	0030964	cellular_component	NADH dehydrogenase complex
L	0042773	biological_process	ATP synthesis coupled electron transport
L	0045271	cellular_component	respiratory chain complex I
L	0048038	molecular_function	quinone binding
M	0003954	molecular_function	NADH dehydrogenase activity
M	0005886	cellular_component	plasma membrane
M	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
M	0009060	biological_process	aerobic respiration
M	0015990	biological_process	electron transport coupled proton transport
M	0016020	cellular_component	membrane
M	0022904	biological_process	respiratory electron transport chain
M	0030964	cellular_component	NADH dehydrogenase complex
M	0042773	biological_process	ATP synthesis coupled electron transport
M	0045271	cellular_component	respiratory chain complex I
M	0048038	molecular_function	quinone binding
M	0048039	molecular_function	ubiquinone binding
N	0003954	molecular_function	NADH dehydrogenase activity
N	0005886	cellular_component	plasma membrane
N	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
N	0009060	biological_process	aerobic respiration
N	0015990	biological_process	electron transport coupled proton transport
N	0016020	cellular_component	membrane
N	0022904	biological_process	respiratory electron transport chain
N	0030964	cellular_component	NADH dehydrogenase complex
N	0042773	biological_process	ATP synthesis coupled electron transport
N	0045271	cellular_component	respiratory chain complex I
N	0048038	molecular_function	quinone binding
N	0050136	molecular_function	NADH dehydrogenase (quinone) (non-electrogenic) activity

Functional Information from PROSITE/UniProt

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GSLQlVaDMIKMFfKE

Chain	Residue	Details
H	GLY56-GLU71

---

site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDQPEAEq.ELadG

Chain	Residue	Details
H	PRO211-GLY224

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	60
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"HAMAP-Rule","id":"MF_01394","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	764
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	336
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	362
Details	Topological domain: {"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	60
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"HAMAP-Rule","id":"MF_01456","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	282
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"HAMAP-Rule","id":"MF_00445","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---