7NX5
Crystal structure of the Epstein-Barr Virus protein ZEBRA (BZLF1, Zta) bound to a methylated DNA duplex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| E | 0003700 | molecular_function | DNA-binding transcription factor activity |
| E | 0006355 | biological_process | regulation of DNA-templated transcription |
| F | 0003700 | molecular_function | DNA-binding transcription factor activity |
| F | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PROSITE/UniProt
| site_id | PS00036 |
| Number of Residues | 15 |
| Details | BZIP_BASIC Basic-leucine zipper (bZIP) domain signature. Kry.KNRvASRKsRAK |
| Chain | Residue | Details |
| A | LYS178-LYS192 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | SITE: Recognition of methylation, required for disruption of latency => ECO:0000269|PubMed:34893887 |
| Chain | Residue | Details |
| A | SER186 | |
| B | SER186 | |
| E | SER186 | |
| F | SER186 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | SITE: Recognition of methylation => ECO:0000269|PubMed:34893887 |
| Chain | Residue | Details |
| A | ARG190 | |
| B | ARG190 | |
| E | ARG190 | |
| F | ARG190 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine; by host => ECO:0000269|PubMed:16321978 |
| Chain | Residue | Details |
| A | SER186 | |
| B | SER186 | |
| E | SER186 | |
| F | SER186 |
