7NW1

Crystal structure of UFC1 in complex with UBA5

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0005515	molecular_function	protein binding
AAA	0005737	cellular_component	cytoplasm
AAA	0007420	biological_process	brain development
AAA	0032649	biological_process	regulation of type II interferon production
AAA	0034976	biological_process	response to endoplasmic reticulum stress
AAA	0061657	molecular_function	UFM1 conjugating enzyme activity
AAA	0061709	biological_process	reticulophagy
AAA	0070062	cellular_component	extracellular exosome
AAA	0071568	molecular_function	UFM1 transferase activity
AAA	0071569	biological_process	protein ufmylation
AAA	1990592	biological_process	protein K69-linked ufmylation
BBB	0005515	molecular_function	protein binding
BBB	0005737	cellular_component	cytoplasm
BBB	0007420	biological_process	brain development
BBB	0032649	biological_process	regulation of type II interferon production
BBB	0034976	biological_process	response to endoplasmic reticulum stress
BBB	0061657	molecular_function	UFM1 conjugating enzyme activity
BBB	0061709	biological_process	reticulophagy
BBB	0070062	cellular_component	extracellular exosome
BBB	0071568	molecular_function	UFM1 transferase activity
BBB	0071569	biological_process	protein ufmylation
BBB	1990592	biological_process	protein K69-linked ufmylation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Glycyl thioester intermediate","evidences":[{"source":"PubMed","id":"15071506","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29868776","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34588452","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in UFM1)","evidences":[{"source":"PubMed","id":"35926457","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q8VE47","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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