7NT4

X-ray structure of SCoV2-PLpro in complex with small molecule inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006508	biological_process	proteolysis
A	0008234	molecular_function	cysteine-type peptidase activity
B	0006508	biological_process	proteolysis
B	0008234	molecular_function	cysteine-type peptidase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	74
Details	ZN_FING: C4-type => ECO:0000255|PROSITE-ProRule:PRU00444

Chain	Residue	Details
A	CYS190-CYS227
B	CYS190-CYS227

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: For PL-PRO activity => ECO:0000255|PROSITE-ProRule:PRU00444, ECO:0000269|PubMed:32726803

Chain	Residue	Details
A	CYS112
B	CYS112

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site_id	SWS_FT_FI3
Number of Residues	4
Details	ACT_SITE: For PL-PRO activity => ECO:0000255|PROSITE-ProRule:PRU00444

Chain	Residue	Details
A	HIS273
A	ASP287
B	HIS273
B	ASP287

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site_id	SWS_FT_FI4
Number of Residues	8
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00444

Chain	Residue	Details
A	CYS190
A	CYS193
A	CYS225
A	CYS227
B	CYS190
B	CYS193
B	CYS225
B	CYS227

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