7NT0

Drosophila PGRP-LB Y78F mutant in complex with tracheal cytotoxin (TCT)

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0002814	biological_process	negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria
AAA	0005515	molecular_function	protein binding
AAA	0005576	cellular_component	extracellular region
AAA	0008270	molecular_function	zinc ion binding
AAA	0008745	molecular_function	N-acetylmuramoyl-L-alanine amidase activity
AAA	0009253	biological_process	peptidoglycan catabolic process
AAA	0016787	molecular_function	hydrolase activity
AAA	0042834	molecular_function	peptidoglycan binding
AAA	0045087	biological_process	innate immune response
AAA	0046872	molecular_function	metal ion binding
AAA	0050830	biological_process	defense response to Gram-positive bacterium
AAA	0061060	biological_process	negative regulation of peptidoglycan recognition protein signaling pathway
BBB	0002814	biological_process	negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria
BBB	0005515	molecular_function	protein binding
BBB	0005576	cellular_component	extracellular region
BBB	0008270	molecular_function	zinc ion binding
BBB	0008745	molecular_function	N-acetylmuramoyl-L-alanine amidase activity
BBB	0009253	biological_process	peptidoglycan catabolic process
BBB	0016787	molecular_function	hydrolase activity
BBB	0042834	molecular_function	peptidoglycan binding
BBB	0045087	biological_process	innate immune response
BBB	0046872	molecular_function	metal ion binding
BBB	0050830	biological_process	defense response to Gram-positive bacterium
BBB	0061060	biological_process	negative regulation of peptidoglycan recognition protein signaling pathway

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:12845326, ECO:0007744|PDB:1OHT

Chain	Residue	Details
BBB	ILE169
BBB	HIS177
AAA	HIS177
BBB	SER59
AAA	SER59
AAA	ILE169

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site_id	SWS_FT_FI2
Number of Residues	2
Details	SITE: Essential for zinc hydrate coordination => ECO:0000303|PubMed:12845326

Chain	Residue	Details
BBB	ASN95
AAA	ASN95

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site_id	SWS_FT_FI3
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
BBB	HIS196
AAA	HIS196

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