7NPA

Crystal structure of the Coenzyme F420-dependent sulfite reductase from Methanothermococcus thermolithotrophicus at 1.55-A resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0016491	molecular_function	oxidoreductase activity
A	0020037	molecular_function	heme binding
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A	0052592	molecular_function	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor
B	0000166	molecular_function	nucleotide binding
B	0016491	molecular_function	oxidoreductase activity
B	0020037	molecular_function	heme binding
B	0046872	molecular_function	metal ion binding
B	0051536	molecular_function	iron-sulfur cluster binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
B	0052592	molecular_function	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor
C	0000166	molecular_function	nucleotide binding
C	0016491	molecular_function	oxidoreductase activity
C	0020037	molecular_function	heme binding
C	0046872	molecular_function	metal ion binding
C	0051536	molecular_function	iron-sulfur cluster binding
C	0051539	molecular_function	4 iron, 4 sulfur cluster binding
C	0052592	molecular_function	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor
D	0000166	molecular_function	nucleotide binding
D	0016491	molecular_function	oxidoreductase activity
D	0020037	molecular_function	heme binding
D	0046872	molecular_function	metal ion binding
D	0051536	molecular_function	iron-sulfur cluster binding
D	0051539	molecular_function	4 iron, 4 sulfur cluster binding
D	0052592	molecular_function	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor
E	0000166	molecular_function	nucleotide binding
E	0016491	molecular_function	oxidoreductase activity
E	0020037	molecular_function	heme binding
E	0046872	molecular_function	metal ion binding
E	0051536	molecular_function	iron-sulfur cluster binding
E	0051539	molecular_function	4 iron, 4 sulfur cluster binding
E	0052592	molecular_function	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor
F	0000166	molecular_function	nucleotide binding
F	0016491	molecular_function	oxidoreductase activity
F	0020037	molecular_function	heme binding
F	0046872	molecular_function	metal ion binding
F	0051536	molecular_function	iron-sulfur cluster binding
F	0051539	molecular_function	4 iron, 4 sulfur cluster binding
F	0052592	molecular_function	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor
G	0000166	molecular_function	nucleotide binding
G	0016491	molecular_function	oxidoreductase activity
G	0020037	molecular_function	heme binding
G	0046872	molecular_function	metal ion binding
G	0051536	molecular_function	iron-sulfur cluster binding
G	0051539	molecular_function	4 iron, 4 sulfur cluster binding
G	0052592	molecular_function	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor
H	0000166	molecular_function	nucleotide binding
H	0016491	molecular_function	oxidoreductase activity
H	0020037	molecular_function	heme binding
H	0046872	molecular_function	metal ion binding
H	0051536	molecular_function	iron-sulfur cluster binding
H	0051539	molecular_function	4 iron, 4 sulfur cluster binding
H	0052592	molecular_function	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor
I	0000166	molecular_function	nucleotide binding
I	0016491	molecular_function	oxidoreductase activity
I	0020037	molecular_function	heme binding
I	0046872	molecular_function	metal ion binding
I	0051536	molecular_function	iron-sulfur cluster binding
I	0051539	molecular_function	4 iron, 4 sulfur cluster binding
I	0052592	molecular_function	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor
J	0000166	molecular_function	nucleotide binding
J	0016491	molecular_function	oxidoreductase activity
J	0020037	molecular_function	heme binding
J	0046872	molecular_function	metal ion binding
J	0051536	molecular_function	iron-sulfur cluster binding
J	0051539	molecular_function	4 iron, 4 sulfur cluster binding
J	0052592	molecular_function	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor
K	0000166	molecular_function	nucleotide binding
K	0016491	molecular_function	oxidoreductase activity
K	0020037	molecular_function	heme binding
K	0046872	molecular_function	metal ion binding
K	0051536	molecular_function	iron-sulfur cluster binding
K	0051539	molecular_function	4 iron, 4 sulfur cluster binding
K	0052592	molecular_function	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor
L	0000166	molecular_function	nucleotide binding
L	0016491	molecular_function	oxidoreductase activity
L	0020037	molecular_function	heme binding
L	0046872	molecular_function	metal ion binding
L	0051536	molecular_function	iron-sulfur cluster binding
L	0051539	molecular_function	4 iron, 4 sulfur cluster binding
L	0052592	molecular_function	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor
M	0000166	molecular_function	nucleotide binding
M	0016491	molecular_function	oxidoreductase activity
M	0020037	molecular_function	heme binding
M	0046872	molecular_function	metal ion binding
M	0051536	molecular_function	iron-sulfur cluster binding
M	0051539	molecular_function	4 iron, 4 sulfur cluster binding
M	0052592	molecular_function	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor
N	0000166	molecular_function	nucleotide binding
N	0016491	molecular_function	oxidoreductase activity
N	0020037	molecular_function	heme binding
N	0046872	molecular_function	metal ion binding
N	0051536	molecular_function	iron-sulfur cluster binding
N	0051539	molecular_function	4 iron, 4 sulfur cluster binding
N	0052592	molecular_function	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor
O	0000166	molecular_function	nucleotide binding
O	0016491	molecular_function	oxidoreductase activity
O	0020037	molecular_function	heme binding
O	0046872	molecular_function	metal ion binding
O	0051536	molecular_function	iron-sulfur cluster binding
O	0051539	molecular_function	4 iron, 4 sulfur cluster binding
O	0052592	molecular_function	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor
P	0000166	molecular_function	nucleotide binding
P	0016491	molecular_function	oxidoreductase activity
P	0020037	molecular_function	heme binding
P	0046872	molecular_function	metal ion binding
P	0051536	molecular_function	iron-sulfur cluster binding
P	0051539	molecular_function	4 iron, 4 sulfur cluster binding
P	0052592	molecular_function	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor

Functional Information from PROSITE/UniProt

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CaKCGtCTvVCP

Chain	Residue	Details
A	CYS15-PRO26
A	CYS524-PRO535

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site_id	PS00365
Number of Residues	17
Details	NIR_SIR Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. SGCpnkCvrpqihDIGI

Chain	Residue	Details
A	SER466-ILE482

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