7NP7
Structure of an intact ESX-5 inner membrane complex, Composite C1 model
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B1 | 0005524 | molecular_function | ATP binding |
| B1 | 0005886 | cellular_component | plasma membrane |
| B1 | 0009274 | cellular_component | peptidoglycan-based cell wall |
| B1 | 0016787 | molecular_function | hydrolase activity |
| B2 | 0005524 | molecular_function | ATP binding |
| B2 | 0005886 | cellular_component | plasma membrane |
| B2 | 0009274 | cellular_component | peptidoglycan-based cell wall |
| B2 | 0016787 | molecular_function | hydrolase activity |
| B3 | 0005524 | molecular_function | ATP binding |
| B3 | 0005886 | cellular_component | plasma membrane |
| B3 | 0009274 | cellular_component | peptidoglycan-based cell wall |
| B3 | 0016787 | molecular_function | hydrolase activity |
| B4 | 0005524 | molecular_function | ATP binding |
| B4 | 0005886 | cellular_component | plasma membrane |
| B4 | 0009274 | cellular_component | peptidoglycan-based cell wall |
| B4 | 0016787 | molecular_function | hydrolase activity |
| B5 | 0005524 | molecular_function | ATP binding |
| B5 | 0005886 | cellular_component | plasma membrane |
| B5 | 0009274 | cellular_component | peptidoglycan-based cell wall |
| B5 | 0016787 | molecular_function | hydrolase activity |
| B6 | 0005524 | molecular_function | ATP binding |
| B6 | 0005886 | cellular_component | plasma membrane |
| B6 | 0009274 | cellular_component | peptidoglycan-based cell wall |
| B6 | 0016787 | molecular_function | hydrolase activity |
| C1 | 0000166 | molecular_function | nucleotide binding |
| C1 | 0003677 | molecular_function | DNA binding |
| C1 | 0005524 | molecular_function | ATP binding |
| C1 | 0005886 | cellular_component | plasma membrane |
| C1 | 0009274 | cellular_component | peptidoglycan-based cell wall |
| C1 | 0016887 | molecular_function | ATP hydrolysis activity |
| C2 | 0000166 | molecular_function | nucleotide binding |
| C2 | 0003677 | molecular_function | DNA binding |
| C2 | 0005524 | molecular_function | ATP binding |
| C2 | 0005886 | cellular_component | plasma membrane |
| C2 | 0009274 | cellular_component | peptidoglycan-based cell wall |
| C2 | 0016887 | molecular_function | ATP hydrolysis activity |
| C3 | 0000166 | molecular_function | nucleotide binding |
| C3 | 0003677 | molecular_function | DNA binding |
| C3 | 0005524 | molecular_function | ATP binding |
| C3 | 0005886 | cellular_component | plasma membrane |
| C3 | 0009274 | cellular_component | peptidoglycan-based cell wall |
| C3 | 0016887 | molecular_function | ATP hydrolysis activity |
| C4 | 0000166 | molecular_function | nucleotide binding |
| C4 | 0003677 | molecular_function | DNA binding |
| C4 | 0005524 | molecular_function | ATP binding |
| C4 | 0005886 | cellular_component | plasma membrane |
| C4 | 0009274 | cellular_component | peptidoglycan-based cell wall |
| C4 | 0016887 | molecular_function | ATP hydrolysis activity |
| C5 | 0000166 | molecular_function | nucleotide binding |
| C5 | 0003677 | molecular_function | DNA binding |
| C5 | 0005524 | molecular_function | ATP binding |
| C5 | 0005886 | cellular_component | plasma membrane |
| C5 | 0009274 | cellular_component | peptidoglycan-based cell wall |
| C5 | 0016887 | molecular_function | ATP hydrolysis activity |
| C6 | 0000166 | molecular_function | nucleotide binding |
| C6 | 0003677 | molecular_function | DNA binding |
| C6 | 0005524 | molecular_function | ATP binding |
| C6 | 0005886 | cellular_component | plasma membrane |
| C6 | 0009274 | cellular_component | peptidoglycan-based cell wall |
| C6 | 0016887 | molecular_function | ATP hydrolysis activity |
| D1 | 0005886 | cellular_component | plasma membrane |
| D2 | 0005886 | cellular_component | plasma membrane |
| D3 | 0005886 | cellular_component | plasma membrane |
| D4 | 0005886 | cellular_component | plasma membrane |
| D5 | 0005886 | cellular_component | plasma membrane |
| D6 | 0005886 | cellular_component | plasma membrane |
| D7 | 0005886 | cellular_component | plasma membrane |
| D8 | 0005886 | cellular_component | plasma membrane |
| D9 | 0005886 | cellular_component | plasma membrane |
| DA | 0005886 | cellular_component | plasma membrane |
| DB | 0005886 | cellular_component | plasma membrane |
| DC | 0005886 | cellular_component | plasma membrane |
| P1 | 0004252 | molecular_function | serine-type endopeptidase activity |
| P1 | 0006508 | biological_process | proteolysis |
| P1 | 0008236 | molecular_function | serine-type peptidase activity |
| P2 | 0004252 | molecular_function | serine-type endopeptidase activity |
| P2 | 0006508 | biological_process | proteolysis |
| P2 | 0008236 | molecular_function | serine-type peptidase activity |
| P3 | 0004252 | molecular_function | serine-type endopeptidase activity |
| P3 | 0006508 | biological_process | proteolysis |
| P3 | 0008236 | molecular_function | serine-type peptidase activity |
Functional Information from PROSITE/UniProt
| site_id | PS00136 |
| Number of Residues | 11 |
| Details | SUBTILASE_ASP Serine proteases, subtilase family, aspartic acid active site. VAVIDTGVtp.H |
| Chain | Residue | Details |
| P3 | VAL105-HIS115 |
| site_id | PS00137 |
| Number of Residues | 11 |
| Details | SUBTILASE_HIS Serine proteases, subtilase family, histidine active site. HGTlVASmIAA |
| Chain | Residue | Details |
| P3 | HIS141-ALA151 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 60 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| P1 | VAL552-PHE572 | |
| D1 | LEU439-ALA459 | |
| DA | ILE137-VAL157 | |
| DA | LEU169-LEU189 | |
| DA | VAL200-PRO220 | |
| DA | VAL224-LEU244 | |
| DA | ARG250-ALA270 | |
| DA | MET272-ALA292 | |
| DA | PHE359-CYS379 | |
| DA | HIS382-LEU402 | |
| DA | SER413-LEU433 | |
| DA | LEU439-ALA459 | |
| D1 | TYR480-ILE500 | |
| DA | TYR480-ILE500 | |
| DB | ILE137-VAL157 | |
| DB | LEU169-LEU189 | |
| DB | VAL200-PRO220 | |
| DB | VAL224-LEU244 | |
| DB | ARG250-ALA270 | |
| DB | MET272-ALA292 | |
| DB | PHE359-CYS379 | |
| DB | HIS382-LEU402 | |
| DB | SER413-LEU433 | |
| D2 | ILE137-VAL157 | |
| DB | LEU439-ALA459 | |
| DB | TYR480-ILE500 | |
| DC | ILE137-VAL157 | |
| DC | LEU169-LEU189 | |
| DC | VAL200-PRO220 | |
| DC | VAL224-LEU244 | |
| DC | ARG250-ALA270 | |
| DC | MET272-ALA292 | |
| DC | PHE359-CYS379 | |
| DC | HIS382-LEU402 | |
| D2 | LEU169-LEU189 | |
| DC | SER413-LEU433 | |
| DC | LEU439-ALA459 | |
| DC | TYR480-ILE500 | |
| D2 | VAL200-PRO220 | |
| D2 | VAL224-LEU244 | |
| D2 | ARG250-ALA270 | |
| D2 | MET272-ALA292 | |
| D2 | PHE359-CYS379 | |
| D2 | HIS382-LEU402 | |
| P2 | VAL552-PHE572 | |
| D2 | SER413-LEU433 | |
| D2 | LEU439-ALA459 | |
| D2 | TYR480-ILE500 | |
| D3 | ILE137-VAL157 | |
| D3 | LEU169-LEU189 | |
| D3 | VAL200-PRO220 | |
| D3 | VAL224-LEU244 | |
| D3 | ARG250-ALA270 | |
| D3 | MET272-ALA292 | |
| D3 | PHE359-CYS379 | |
| P3 | VAL552-PHE572 | |
| D3 | HIS382-LEU402 | |
| D3 | SER413-LEU433 | |
| D3 | LEU439-ALA459 | |
| D3 | TYR480-ILE500 | |
| D4 | ILE137-VAL157 | |
| D4 | LEU169-LEU189 | |
| D4 | VAL200-PRO220 | |
| D4 | VAL224-LEU244 | |
| D4 | ARG250-ALA270 | |
| D4 | MET272-ALA292 | |
| D1 | VAL224-LEU244 | |
| D4 | PHE359-CYS379 | |
| D4 | HIS382-LEU402 | |
| D4 | SER413-LEU433 | |
| D4 | LEU439-ALA459 | |
| D4 | TYR480-ILE500 | |
| D5 | ILE137-VAL157 | |
| D5 | LEU169-LEU189 | |
| D5 | VAL200-PRO220 | |
| D5 | VAL224-LEU244 | |
| D5 | ARG250-ALA270 | |
| D1 | ARG250-ALA270 | |
| D5 | MET272-ALA292 | |
| D5 | PHE359-CYS379 | |
| D5 | HIS382-LEU402 | |
| D5 | SER413-LEU433 | |
| D5 | LEU439-ALA459 | |
| D5 | TYR480-ILE500 | |
| D6 | ILE137-VAL157 | |
| D6 | LEU169-LEU189 | |
| D6 | VAL200-PRO220 | |
| D6 | VAL224-LEU244 | |
| D1 | MET272-ALA292 | |
| D6 | ARG250-ALA270 | |
| D6 | MET272-ALA292 | |
| D6 | PHE359-CYS379 | |
| D6 | HIS382-LEU402 | |
| D6 | SER413-LEU433 | |
| D6 | LEU439-ALA459 | |
| D6 | TYR480-ILE500 | |
| D7 | ILE137-VAL157 | |
| D7 | LEU169-LEU189 | |
| D7 | VAL200-PRO220 | |
| D1 | PHE359-CYS379 | |
| D7 | VAL224-LEU244 | |
| D7 | ARG250-ALA270 | |
| D7 | MET272-ALA292 | |
| D7 | PHE359-CYS379 | |
| D7 | HIS382-LEU402 | |
| D7 | SER413-LEU433 | |
| D7 | LEU439-ALA459 | |
| D7 | TYR480-ILE500 | |
| D8 | ILE137-VAL157 | |
| D8 | LEU169-LEU189 | |
| D1 | HIS382-LEU402 | |
| D8 | VAL200-PRO220 | |
| D8 | VAL224-LEU244 | |
| D8 | ARG250-ALA270 | |
| D8 | MET272-ALA292 | |
| D8 | PHE359-CYS379 | |
| D8 | HIS382-LEU402 | |
| D8 | SER413-LEU433 | |
| D8 | LEU439-ALA459 | |
| D8 | TYR480-ILE500 | |
| D9 | ILE137-VAL157 | |
| D1 | SER413-LEU433 | |
| D9 | LEU169-LEU189 | |
| D9 | VAL200-PRO220 | |
| D9 | VAL224-LEU244 | |
| D9 | ARG250-ALA270 | |
| D9 | MET272-ALA292 | |
| D9 | PHE359-CYS379 | |
| D9 | HIS382-LEU402 | |
| D9 | SER413-LEU433 | |
| D9 | LEU439-ALA459 | |
| D9 | TYR480-ILE500 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | ACT_SITE: Charge relay system => ECO:0000255|PROSITE-ProRule:PRU01240 |
| Chain | Residue | Details |
| P1 | ASP109 | |
| C4 | GLY499 | |
| C4 | GLY876 | |
| C4 | GLY1178 | |
| C5 | GLY499 | |
| C5 | GLY876 | |
| C5 | GLY1178 | |
| C6 | GLY499 | |
| C6 | GLY876 | |
| C6 | GLY1178 | |
| P1 | HIS141 | |
| P1 | SER466 | |
| P2 | ASP109 | |
| P2 | HIS141 | |
| P2 | SER466 | |
| P3 | ASP109 | |
| P3 | HIS141 | |
| P3 | SER466 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2574 |
| Details | TOPO_DOM: Periplasmic => ECO:0000305 |
| Chain | Residue | Details |
| B1 | SER77-LYS506 | |
| B2 | SER77-LYS506 | |
| B3 | SER77-LYS506 | |
| B4 | SER77-LYS506 | |
| B5 | SER77-LYS506 | |
| B6 | SER77-LYS506 |
