7NNG

Crystal structure of the SARS-CoV-2 helicase in complex with Z2327226104

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004386	molecular_function	helicase activity
A	0005524	molecular_function	ATP binding
A	0008270	molecular_function	zinc ion binding
B	0004386	molecular_function	helicase activity
B	0005524	molecular_function	ATP binding
B	0008270	molecular_function	zinc ion binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00986, ECO:0000269|PubMed:33232691, ECO:0007744|PDB:7CYQ

Chain	Residue	Details
B	CYS5
B	CYS55
B	CYS72
B	HIS75
A	CYS5
A	CYS8
A	CYS16
A	CYS19
A	CYS26
A	CYS29
A	HIS33
B	CYS8
A	HIS39
A	CYS50
A	CYS55
A	CYS72
A	HIS75
B	CYS16
B	CYS19
B	CYS26
B	CYS29
B	HIS33
B	HIS39
B	CYS50

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00990

Chain	Residue	Details
B	GLY282
A	GLY282

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site_id	SWS_FT_FI3
Number of Residues	2
Details	SITE: Cleavage; by 3CL-PRO => ECO:0000250|UniProtKB:P0C6V3

Chain	Residue	Details
B	GLN601
A	GLN601

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