Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue PGE A 401 |
| Chain | Residue |
| A | GLU13 |
| A | SER252 |
| A | EDO402 |
| B | TRP125 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 402 |
| Chain | Residue |
| A | HOH715 |
| A | TYR251 |
| A | SER252 |
| A | TRP253 |
| A | ARG379 |
| A | PGE401 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 403 |
| Chain | Residue |
| A | PHE127 |
| A | ASP129 |
| A | HOH743 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue PEG A 404 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 405 |
| Chain | Residue |
| A | TRP253 |
| A | SER310 |
| A | ASP345 |
| A | GLY346 |
| A | ARG379 |
| C | TRP253 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 406 |
| Chain | Residue |
| A | GLN370 |
| A | HOH531 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 407 |
| Chain | Residue |
| A | GLN266 |
| A | ARG279 |
| A | GLU280 |
| A | PHE281 |
| A | LYS282 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 408 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 401 |
| Chain | Residue |
| B | ASN121 |
| B | TRP122 |
| B | GLN123 |
| B | HOH516 |
| D | HIS348 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue PEG B 402 |
| Chain | Residue |
| B | ARG327 |
| B | LYS328 |
| B | GLU331 |
| B | ALA336 |
| B | HOH657 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue PEG B 403 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 404 |
| Chain | Residue |
| B | GLN370 |
| B | HOH523 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 405 |
| Chain | Residue |
| B | SER72 |
| B | ASN74 |
| B | HOH534 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue PEG B 406 |
| Chain | Residue |
| B | ARG285 |
| B | GLN286 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue ACT B 407 |
| Chain | Residue |
| B | LYS193 |
| B | HOH519 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 401 |
| Chain | Residue |
| C | GLY248 |
| C | HOH700 |
| D | ASN74 |
| D | THR79 |
| D | EDO402 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 402 |
| Chain | Residue |
| A | HIS348 |
| C | ASN121 |
| C | TRP122 |
| C | HOH562 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 403 |
| Chain | Residue |
| C | ALA227 |
| C | THR302 |
| C | ARG338 |
| C | HOH528 |
| site_id | AE1 |
| Number of Residues | 1 |
| Details | binding site for residue EDO C 404 |
| site_id | AE2 |
| Number of Residues | 2 |
| Details | binding site for residue PGE C 405 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 406 |
| Chain | Residue |
| A | VAL255 |
| C | ARG379 |
| C | HOH501 |
| C | HOH519 |
| C | HOH522 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 407 |
| Chain | Residue |
| A | TRP312 |
| C | ARG344 |
| C | ASP345 |
| C | GLU353 |
| C | ARG379 |
| C | HOH522 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 408 |
| Chain | Residue |
| C | GLN47 |
| C | ASP51 |
| C | GLN54 |
| C | LYS61 |
| C | HOH619 |
| site_id | AE6 |
| Number of Residues | 2 |
| Details | binding site for residue EDO C 409 |
| Chain | Residue |
| C | LEU366 |
| C | ARG367 |
| site_id | AE7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 401 |
| Chain | Residue |
| A | ASP374 |
| A | THR377 |
| D | ARG151 |
| D | ASP153 |
| D | HOH574 |
| D | HOH577 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 402 |
| Chain | Residue |
| C | EDO401 |
| D | SER72 |
| D | THR79 |
| D | HOH558 |
| site_id | AE9 |
| Number of Residues | 2 |
| Details | binding site for residue EDO D 403 |
| Chain | Residue |
| D | ARG379 |
| D | HOH747 |
| site_id | AF1 |
| Number of Residues | 2 |
| Details | binding site for residue EDO D 404 |
| Chain | Residue |
| D | PHE127 |
| D | HOH529 |
| site_id | AF2 |
| Number of Residues | 1 |
| Details | binding site for residue PEG D 405 |
| site_id | AF3 |
| Number of Residues | 4 |
| Details | binding site for residue PEG D 406 |
| Chain | Residue |
| D | GLN266 |
| D | GLY267 |
| D | ARG279 |
| D | SER263 |
| site_id | AF4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 407 |
| Chain | Residue |
| D | PRO165 |
| D | HIS166 |
| D | SER167 |
| D | ASN172 |
| site_id | AF5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 408 |
| Chain | Residue |
| D | LEU191 |
| D | GLU192 |
| D | ALA201 |
| site_id | AF6 |
| Number of Residues | 12 |
| Details | binding site for residue PEG D 409 |
| Chain | Residue |
| D | LYS61 |
| D | THR64 |
| D | ALA181 |
| D | TRP182 |
| D | SER185 |
| D | LYS186 |
| D | VAL218 |
| D | ALA219 |
| D | PHE222 |
| D | ASP223 |
| D | HOH548 |
| D | HOH589 |
| site_id | AF7 |
| Number of Residues | 1 |
| Details | binding site for residue EDO D 410 |
