7NLW

Crystal structure of Mycobacterium tuberculosis ArgB in complex with 2-(5-methoxy-1H-indol-3-yl)acetonitrile

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003991	molecular_function	acetylglutamate kinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005886	cellular_component	plasma membrane
A	0006526	biological_process	arginine biosynthetic process
A	0009274	cellular_component	peptidoglycan-based cell wall
A	0016301	molecular_function	kinase activity
A	0042450	biological_process	arginine biosynthetic process via ornithine

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue UOK A 301

Chain	Residue
A	VAL125
A	VAL125
A	ILE127
A	ALA132
A	ARG173
A	ARG173

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site_id	AC2
Number of Residues	4
Details	binding site for residue SO4 A 302

Chain	Residue
A	LYS290
A	TRP22
A	LYS208
A	HIS267

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site_id	AC3
Number of Residues	6
Details	binding site for residue SO4 A 303

Chain	Residue
A	ARG78
A	ARG78
A	PHE86
A	PHE86
A	ARG91
A	ARG91

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00082

Chain	Residue	Details
A	GLY69
A	ARG91
A	ASN190

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site_id	SWS_FT_FI2
Number of Residues	2
Details	SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00082

Chain	Residue	Details
A	LYS34
A	LYS251

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