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7NLO

Crystal structure of Mycobacterium tuberculosis ArgB in complex with L-arginine

Functional Information from GO Data
ChainGOidnamespacecontents
A0003991molecular_functionacetylglutamate kinase activity
A0005524molecular_functionATP binding
A0005737cellular_componentcytoplasm
A0005886cellular_componentplasma membrane
A0006526biological_processL-arginine biosynthetic process
A0009274cellular_componentpeptidoglycan-based cell wall
A0016301molecular_functionkinase activity
A0042450biological_processarginine biosynthetic process via ornithine
Functional Information from PDB Data
site_idAC1
Number of Residues13
Detailsbinding site for residue ARG A 301
ChainResidue
ATRP22
AGLY286
AGLY288
ATHR289
ALYS290
ALYS208
ASER230
AHIS267
AGLU280
ALEU281
ATHR283
AASP284
AALA285

site_idAC2
Number of Residues9
Detailsbinding site for residue NHE A 302
ChainResidue
AASP99
AARG102
AASN115
AASP185
AGLY186
AVAL188
AHOH404
AHOH437
AHOH474

site_idAC3
Number of Residues4
Detailsbinding site for residue EDO A 303
ChainResidue
ATHR74
AARG78
AARG91
AHOH456

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00082
ChainResidueDetails
AGLY69
AARG91
AASN190

site_idSWS_FT_FI2
Number of Residues2
DetailsSITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00082
ChainResidueDetails
ALYS34
ALYS251

227344

PDB entries from 2024-11-13

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