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7NK6

1918 H1N1 Viral influenza polymerase heterotrimer with Nb8204

Functional Information from GO Data
ChainGOidnamespacecontents
A0003723molecular_functionRNA binding
A0004519molecular_functionendonuclease activity
A0006351biological_processDNA-templated transcription
A0030430cellular_componenthost cell cytoplasm
A0039523biological_processsymbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
A0039657biological_processsymbiont-mediated suppression of host gene expression
A0039694biological_processviral RNA genome replication
A0042025cellular_componenthost cell nucleus
A0046872molecular_functionmetal ion binding
A0075523biological_processviral translational frameshifting
A0075526biological_processcap snatching
B0000166molecular_functionnucleotide binding
B0001172biological_processRNA-templated transcription
B0003723molecular_functionRNA binding
B0003968molecular_functionRNA-dependent RNA polymerase activity
B0006351biological_processDNA-templated transcription
B0019083biological_processviral transcription
B0030430cellular_componenthost cell cytoplasm
B0034062molecular_function5'-3' RNA polymerase activity
B0039523biological_processsymbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
B0039657biological_processsymbiont-mediated suppression of host gene expression
B0039694biological_processviral RNA genome replication
B0042025cellular_componenthost cell nucleus
C0001172biological_processRNA-templated transcription
C0003723molecular_functionRNA binding
C0003968molecular_functionRNA-dependent RNA polymerase activity
C0006351biological_processDNA-templated transcription
C0006370biological_process7-methylguanosine mRNA capping
C0019049biological_processvirus-mediated perturbation of host defense response
C0019083biological_processviral transcription
C0019865molecular_functionimmunoglobulin binding
C0033650cellular_componenthost cell mitochondrion
C0039523biological_processsymbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
C0039545biological_processsymbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
C0039657biological_processsymbiont-mediated suppression of host gene expression
C0039694biological_processviral RNA genome replication
C0042025cellular_componenthost cell nucleus
C0044423cellular_componentvirion component
C0075526biological_processcap snatching
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsSITE: Mammalian adaptation => ECO:0000255|HAMAP-Rule:MF_04062
ChainResidueDetails
CLYS627
AGLU80
AASP108
AGLU119
AILE120

227561

PDB entries from 2024-11-20

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