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7NIE

putative glycerol kinase-like proteins anchored on an array of voltage dependent anion channels in the outer mitochondrial membrane of pig sperm mitochondria

Functional Information from GO Data
ChainGOidnamespacecontents
A0004370molecular_functionglycerol kinase activity
A0005739cellular_componentmitochondrion
A0005975biological_processcarbohydrate metabolic process
A0006071biological_processglycerol metabolic process
A0006641biological_processtriglyceride metabolic process
A0016301molecular_functionkinase activity
A0016310biological_processphosphorylation
A0016773molecular_functionphosphotransferase activity, alcohol group as acceptor
A0019563biological_processglycerol catabolic process
A0046167biological_processglycerol-3-phosphate biosynthetic process
B0004370molecular_functionglycerol kinase activity
B0005739cellular_componentmitochondrion
B0005975biological_processcarbohydrate metabolic process
B0006071biological_processglycerol metabolic process
B0006641biological_processtriglyceride metabolic process
B0016301molecular_functionkinase activity
B0016310biological_processphosphorylation
B0016773molecular_functionphosphotransferase activity, alcohol group as acceptor
B0019563biological_processglycerol catabolic process
B0046167biological_processglycerol-3-phosphate biosynthetic process
C0005524molecular_functionATP binding
C0005739cellular_componentmitochondrion
C0005741cellular_componentmitochondrial outer membrane
C0006811biological_processmonoatomic ion transport
C0006869biological_processlipid transport
C0008142molecular_functionoxysterol binding
C0008289molecular_functionlipid binding
C0008308molecular_functionvoltage-gated monoatomic anion channel activity
C0015288molecular_functionporin activity
C0015485molecular_functioncholesterol binding
C0016020cellular_componentmembrane
C0031210molecular_functionphosphatidylcholine binding
C0046930cellular_componentpore complex
C0055085biological_processtransmembrane transport
C0097001molecular_functionceramide binding
C0097225cellular_componentsperm midpiece
C0097345biological_processmitochondrial outer membrane permeabilization
C0098656biological_processmonoatomic anion transmembrane transport
D0005524molecular_functionATP binding
D0005739cellular_componentmitochondrion
D0005741cellular_componentmitochondrial outer membrane
D0006811biological_processmonoatomic ion transport
D0006869biological_processlipid transport
D0008142molecular_functionoxysterol binding
D0008289molecular_functionlipid binding
D0008308molecular_functionvoltage-gated monoatomic anion channel activity
D0015288molecular_functionporin activity
D0015485molecular_functioncholesterol binding
D0016020cellular_componentmembrane
D0031210molecular_functionphosphatidylcholine binding
D0046930cellular_componentpore complex
D0055085biological_processtransmembrane transport
D0097001molecular_functionceramide binding
D0097225cellular_componentsperm midpiece
D0097345biological_processmitochondrial outer membrane permeabilization
D0098656biological_processmonoatomic anion transmembrane transport
E0005524molecular_functionATP binding
E0005739cellular_componentmitochondrion
E0005741cellular_componentmitochondrial outer membrane
E0006811biological_processmonoatomic ion transport
E0006869biological_processlipid transport
E0008142molecular_functionoxysterol binding
E0008289molecular_functionlipid binding
E0008308molecular_functionvoltage-gated monoatomic anion channel activity
E0015288molecular_functionporin activity
E0015485molecular_functioncholesterol binding
E0016020cellular_componentmembrane
E0031210molecular_functionphosphatidylcholine binding
E0046930cellular_componentpore complex
E0055085biological_processtransmembrane transport
E0097001molecular_functionceramide binding
E0097225cellular_componentsperm midpiece
E0097345biological_processmitochondrial outer membrane permeabilization
E0098656biological_processmonoatomic anion transmembrane transport
F0005524molecular_functionATP binding
F0005739cellular_componentmitochondrion
F0005741cellular_componentmitochondrial outer membrane
F0006811biological_processmonoatomic ion transport
F0006869biological_processlipid transport
F0008142molecular_functionoxysterol binding
F0008289molecular_functionlipid binding
F0008308molecular_functionvoltage-gated monoatomic anion channel activity
F0015288molecular_functionporin activity
F0015485molecular_functioncholesterol binding
F0016020cellular_componentmembrane
F0031210molecular_functionphosphatidylcholine binding
F0046930cellular_componentpore complex
F0055085biological_processtransmembrane transport
F0097001molecular_functionceramide binding
F0097225cellular_componentsperm midpiece
F0097345biological_processmitochondrial outer membrane permeabilization
F0098656biological_processmonoatomic anion transmembrane transport
G0005524molecular_functionATP binding
G0005739cellular_componentmitochondrion
G0005741cellular_componentmitochondrial outer membrane
G0006811biological_processmonoatomic ion transport
G0006869biological_processlipid transport
G0008142molecular_functionoxysterol binding
G0008289molecular_functionlipid binding
G0008308molecular_functionvoltage-gated monoatomic anion channel activity
G0015288molecular_functionporin activity
G0015485molecular_functioncholesterol binding
G0016020cellular_componentmembrane
G0031210molecular_functionphosphatidylcholine binding
G0046930cellular_componentpore complex
G0055085biological_processtransmembrane transport
G0097001molecular_functionceramide binding
G0097225cellular_componentsperm midpiece
G0097345biological_processmitochondrial outer membrane permeabilization
G0098656biological_processmonoatomic anion transmembrane transport
H0005524molecular_functionATP binding
H0005739cellular_componentmitochondrion
H0005741cellular_componentmitochondrial outer membrane
H0006811biological_processmonoatomic ion transport
H0006869biological_processlipid transport
H0008142molecular_functionoxysterol binding
H0008289molecular_functionlipid binding
H0008308molecular_functionvoltage-gated monoatomic anion channel activity
H0015288molecular_functionporin activity
H0015485molecular_functioncholesterol binding
H0016020cellular_componentmembrane
H0031210molecular_functionphosphatidylcholine binding
H0046930cellular_componentpore complex
H0055085biological_processtransmembrane transport
H0097001molecular_functionceramide binding
H0097225cellular_componentsperm midpiece
H0097345biological_processmitochondrial outer membrane permeabilization
H0098656biological_processmonoatomic anion transmembrane transport
I0005524molecular_functionATP binding
I0005739cellular_componentmitochondrion
I0005741cellular_componentmitochondrial outer membrane
I0006811biological_processmonoatomic ion transport
I0006869biological_processlipid transport
I0008142molecular_functionoxysterol binding
I0008289molecular_functionlipid binding
I0008308molecular_functionvoltage-gated monoatomic anion channel activity
I0015288molecular_functionporin activity
I0015485molecular_functioncholesterol binding
I0016020cellular_componentmembrane
I0031210molecular_functionphosphatidylcholine binding
I0046930cellular_componentpore complex
I0055085biological_processtransmembrane transport
I0097001molecular_functionceramide binding
I0097225cellular_componentsperm midpiece
I0097345biological_processmitochondrial outer membrane permeabilization
I0098656biological_processmonoatomic anion transmembrane transport
J0005524molecular_functionATP binding
J0005739cellular_componentmitochondrion
J0005741cellular_componentmitochondrial outer membrane
J0006811biological_processmonoatomic ion transport
J0006869biological_processlipid transport
J0008142molecular_functionoxysterol binding
J0008289molecular_functionlipid binding
J0008308molecular_functionvoltage-gated monoatomic anion channel activity
J0015288molecular_functionporin activity
J0015485molecular_functioncholesterol binding
J0016020cellular_componentmembrane
J0031210molecular_functionphosphatidylcholine binding
J0046930cellular_componentpore complex
J0055085biological_processtransmembrane transport
J0097001molecular_functionceramide binding
J0097225cellular_componentsperm midpiece
J0097345biological_processmitochondrial outer membrane permeabilization
J0098656biological_processmonoatomic anion transmembrane transport
K0005524molecular_functionATP binding
K0005739cellular_componentmitochondrion
K0005741cellular_componentmitochondrial outer membrane
K0006811biological_processmonoatomic ion transport
K0006869biological_processlipid transport
K0008142molecular_functionoxysterol binding
K0008289molecular_functionlipid binding
K0008308molecular_functionvoltage-gated monoatomic anion channel activity
K0015288molecular_functionporin activity
K0015485molecular_functioncholesterol binding
K0016020cellular_componentmembrane
K0031210molecular_functionphosphatidylcholine binding
K0046930cellular_componentpore complex
K0055085biological_processtransmembrane transport
K0097001molecular_functionceramide binding
K0097225cellular_componentsperm midpiece
K0097345biological_processmitochondrial outer membrane permeabilization
K0098656biological_processmonoatomic anion transmembrane transport
L0005524molecular_functionATP binding
L0005739cellular_componentmitochondrion
L0005741cellular_componentmitochondrial outer membrane
L0006811biological_processmonoatomic ion transport
L0006869biological_processlipid transport
L0008142molecular_functionoxysterol binding
L0008289molecular_functionlipid binding
L0008308molecular_functionvoltage-gated monoatomic anion channel activity
L0015288molecular_functionporin activity
L0015485molecular_functioncholesterol binding
L0016020cellular_componentmembrane
L0031210molecular_functionphosphatidylcholine binding
L0046930cellular_componentpore complex
L0055085biological_processtransmembrane transport
L0097001molecular_functionceramide binding
L0097225cellular_componentsperm midpiece
L0097345biological_processmitochondrial outer membrane permeabilization
L0098656biological_processmonoatomic anion transmembrane transport
M0005524molecular_functionATP binding
M0005739cellular_componentmitochondrion
M0005741cellular_componentmitochondrial outer membrane
M0006811biological_processmonoatomic ion transport
M0006869biological_processlipid transport
M0008142molecular_functionoxysterol binding
M0008289molecular_functionlipid binding
M0008308molecular_functionvoltage-gated monoatomic anion channel activity
M0015288molecular_functionporin activity
M0015485molecular_functioncholesterol binding
M0016020cellular_componentmembrane
M0031210molecular_functionphosphatidylcholine binding
M0046930cellular_componentpore complex
M0055085biological_processtransmembrane transport
M0097001molecular_functionceramide binding
M0097225cellular_componentsperm midpiece
M0097345biological_processmitochondrial outer membrane permeabilization
M0098656biological_processmonoatomic anion transmembrane transport
N0005524molecular_functionATP binding
N0005739cellular_componentmitochondrion
N0005741cellular_componentmitochondrial outer membrane
N0006811biological_processmonoatomic ion transport
N0006869biological_processlipid transport
N0008142molecular_functionoxysterol binding
N0008289molecular_functionlipid binding
N0008308molecular_functionvoltage-gated monoatomic anion channel activity
N0015288molecular_functionporin activity
N0015485molecular_functioncholesterol binding
N0016020cellular_componentmembrane
N0031210molecular_functionphosphatidylcholine binding
N0046930cellular_componentpore complex
N0055085biological_processtransmembrane transport
N0097001molecular_functionceramide binding
N0097225cellular_componentsperm midpiece
N0097345biological_processmitochondrial outer membrane permeabilization
N0098656biological_processmonoatomic anion transmembrane transport
O0004370molecular_functionglycerol kinase activity
O0005739cellular_componentmitochondrion
O0005975biological_processcarbohydrate metabolic process
O0006071biological_processglycerol metabolic process
O0006641biological_processtriglyceride metabolic process
O0016301molecular_functionkinase activity
O0016310biological_processphosphorylation
O0016773molecular_functionphosphotransferase activity, alcohol group as acceptor
O0019563biological_processglycerol catabolic process
O0046167biological_processglycerol-3-phosphate biosynthetic process
P0004370molecular_functionglycerol kinase activity
P0005739cellular_componentmitochondrion
P0005975biological_processcarbohydrate metabolic process
P0006071biological_processglycerol metabolic process
P0006641biological_processtriglyceride metabolic process
P0016301molecular_functionkinase activity
P0016310biological_processphosphorylation
P0016773molecular_functionphosphotransferase activity, alcohol group as acceptor
P0019563biological_processglycerol catabolic process
P0046167biological_processglycerol-3-phosphate biosynthetic process
Functional Information from PROSITE/UniProt
site_idPS00445
Number of Residues21
DetailsFGGY_KINASES_2 FGGY family of carbohydrate kinases signature 2. GiICGLtqftnkc.HIAFAALE
ChainResidueDetails
AGLY351-GLU371

site_idPS00558
Number of Residues23
DetailsEUKARYOTIC_PORIN Eukaryotic mitochondrial porin signature. YqlDPtAsisAKVNNssliGVgY
ChainResidueDetails
CTYR236-TYR258

site_idPS00933
Number of Residues13
DetailsFGGY_KINASES_1 FGGY family of carbohydrate kinases signature 1. YfSavKLRWLLDN
ChainResidueDetails
ATYR148-ASN160

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1968
DetailsTRANSMEM: Beta stranded => ECO:0000250|UniProtKB:P21796
ChainResidueDetails
CLEU37-SER46
CVAL50-SER58
CVAL65-TRP75
CLEU80-ASN87
CTHR91-ASP100
CLEU106-SER115
CSER122-ARG131
CVAL134-ASP141
CALA148-GLY156
CLEU161-ASP169
CLYS174-THR186
CPHE189-ASN196
CGLU200-VAL209
CLEU213-THR222
CARG229-LEU238
CALA242-ASN249
CLEU253-LEU262
CGLY265-VAL274
CHIS284-GLU293
DLEU37-SER46
DVAL50-SER58
DVAL65-TRP75
DLEU80-ASN87
DTHR91-ASP100
DLEU106-SER115
DSER122-ARG131
DVAL134-ASP141
DALA148-GLY156
DLEU161-ASP169
DLYS174-THR186
DPHE189-ASN196
DGLU200-VAL209
DLEU213-THR222
DARG229-LEU238
DALA242-ASN249
DLEU253-LEU262
DGLY265-VAL274
DHIS284-GLU293
ELEU37-SER46
EVAL50-SER58
EVAL65-TRP75
ELEU80-ASN87
ETHR91-ASP100
ELEU106-SER115
ESER122-ARG131
EVAL134-ASP141
EALA148-GLY156
ELEU161-ASP169
ELYS174-THR186
EPHE189-ASN196
EGLU200-VAL209
ELEU213-THR222
EARG229-LEU238
EALA242-ASN249
ELEU253-LEU262
EGLY265-VAL274
EHIS284-GLU293
FLEU37-SER46
FVAL50-SER58
FVAL65-TRP75
FLEU80-ASN87
FTHR91-ASP100
FLEU106-SER115
FSER122-ARG131
FVAL134-ASP141
FALA148-GLY156
FLEU161-ASP169
FLYS174-THR186
FPHE189-ASN196
FGLU200-VAL209
FLEU213-THR222
FARG229-LEU238
FALA242-ASN249
FLEU253-LEU262
FGLY265-VAL274
FHIS284-GLU293
GLEU37-SER46
GVAL50-SER58
GVAL65-TRP75
GLEU80-ASN87
GTHR91-ASP100
GLEU106-SER115
GSER122-ARG131
GVAL134-ASP141
GALA148-GLY156
GLEU161-ASP169
GLYS174-THR186
GPHE189-ASN196
GGLU200-VAL209
GLEU213-THR222
GARG229-LEU238
GALA242-ASN249
GLEU253-LEU262
GGLY265-VAL274
GHIS284-GLU293
HLEU37-SER46
HVAL50-SER58
HVAL65-TRP75
HLEU80-ASN87
HTHR91-ASP100
HLEU106-SER115
HSER122-ARG131
HVAL134-ASP141
HALA148-GLY156
HLEU161-ASP169
HLYS174-THR186
HPHE189-ASN196
HGLU200-VAL209
HLEU213-THR222
HARG229-LEU238
HALA242-ASN249
HLEU253-LEU262
HGLY265-VAL274
HHIS284-GLU293
ILEU37-SER46
IVAL50-SER58
IVAL65-TRP75
ILEU80-ASN87
ITHR91-ASP100
ILEU106-SER115
ISER122-ARG131
IVAL134-ASP141
IALA148-GLY156
ILEU161-ASP169
ILYS174-THR186
IPHE189-ASN196
IGLU200-VAL209
ILEU213-THR222
IARG229-LEU238
IALA242-ASN249
ILEU253-LEU262
IGLY265-VAL274
IHIS284-GLU293
JLEU37-SER46
JVAL50-SER58
JVAL65-TRP75
JLEU80-ASN87
JTHR91-ASP100
JLEU106-SER115
JSER122-ARG131
JVAL134-ASP141
JALA148-GLY156
JLEU161-ASP169
JLYS174-THR186
JPHE189-ASN196
JGLU200-VAL209
JLEU213-THR222
JARG229-LEU238
JALA242-ASN249
JLEU253-LEU262
JGLY265-VAL274
JHIS284-GLU293
KLEU37-SER46
KVAL50-SER58
KVAL65-TRP75
KLEU80-ASN87
KTHR91-ASP100
KLEU106-SER115
KSER122-ARG131
KVAL134-ASP141
KALA148-GLY156
KLEU161-ASP169
KLYS174-THR186
KPHE189-ASN196
KGLU200-VAL209
KLEU213-THR222
KARG229-LEU238
KALA242-ASN249
KLEU253-LEU262
KGLY265-VAL274
KHIS284-GLU293
LLEU37-SER46
LVAL50-SER58
LVAL65-TRP75
LLEU80-ASN87
LTHR91-ASP100
LLEU106-SER115
LSER122-ARG131
LVAL134-ASP141
LALA148-GLY156
LLEU161-ASP169
LLYS174-THR186
LPHE189-ASN196
LGLU200-VAL209
LLEU213-THR222
LARG229-LEU238
LALA242-ASN249
LLEU253-LEU262
LGLY265-VAL274
LHIS284-GLU293
MLEU37-SER46
MVAL50-SER58
MVAL65-TRP75
MLEU80-ASN87
MTHR91-ASP100
MLEU106-SER115
MSER122-ARG131
MVAL134-ASP141
MALA148-GLY156
MLEU161-ASP169
MLYS174-THR186
MPHE189-ASN196
MGLU200-VAL209
MLEU213-THR222
MARG229-LEU238
MALA242-ASN249
MLEU253-LEU262
MGLY265-VAL274
MHIS284-GLU293
NLEU37-SER46
NVAL50-SER58
NVAL65-TRP75
NLEU80-ASN87
NTHR91-ASP100
NLEU106-SER115
NSER122-ARG131
NVAL134-ASP141
NALA148-GLY156
NLEU161-ASP169
NLYS174-THR186
NPHE189-ASN196
NGLU200-VAL209
NLEU213-THR222
NARG229-LEU238
NALA242-ASN249
NLEU253-LEU262
NGLY265-VAL274
NHIS284-GLU293

site_idSWS_FT_FI2
Number of Residues24
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:Q60932
ChainResidueDetails
CLYS23
CLYS31
DLYS23
DLYS31
ELYS23
ELYS31
FLYS23
FLYS31
GLYS23
GLYS31
HLYS23
HLYS31
ILYS23
ILYS31
JLYS23
JLYS31
KLYS23
KLYS31
LLYS23
LLYS31
MLYS23
MLYS31
NLYS23
NLYS31

site_idSWS_FT_FI3
Number of Residues24
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:P21796
ChainResidueDetails
HSER271
ILEU253
ISER271
JLEU253
JSER271
KLEU253
KSER271
LLEU253
LSER271
MLEU253
MSER271
NLEU253
NSER271
CLEU253
CSER271
DLEU253
DSER271
ELEU253
ESER271
FLEU253
FSER271
GLEU253
GSER271
HLEU253

site_idSWS_FT_FI4
Number of Residues12
DetailsSITE: Involved in ceramide and phosphatidylcholine binding => ECO:0000250|UniProtKB:P45880
ChainResidueDetails
CLYS85
DLYS85
ELYS85
FLYS85
GLYS85
HLYS85
ILYS85
JLYS85
KLYS85
LLYS85
MLYS85
NLYS85

site_idSWS_FT_FI5
Number of Residues12
DetailsMOD_RES: N-acetylalanine => ECO:0000250|UniProtKB:P45880
ChainResidueDetails
CALA2
DALA2
EALA2
FALA2
GALA2
HALA2
IALA2
JALA2
KALA2
LALA2
MALA2
NALA2

site_idSWS_FT_FI6
Number of Residues12
DetailsMOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q60930
ChainResidueDetails
DLYS31
CLYS31
ELYS31
FLYS31
GLYS31
HLYS31
ILYS31
JLYS31
KLYS31
LLYS31
MLYS31
NLYS31

site_idSWS_FT_FI7
Number of Residues12
DetailsMOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:Q60932
ChainResidueDetails
DTYR78
CTYR78
ETYR78
FTYR78
GTYR78
HTYR78
ITYR78
JTYR78
KTYR78
LTYR78
MTYR78
NTYR78

site_idSWS_FT_FI8
Number of Residues12
DetailsMOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P21796
ChainResidueDetails
CTHR118
DTHR118
ETHR118
FTHR118
GTHR118
HTHR118
ITHR118
JTHR118
KTHR118
LTHR118
MTHR118
NTHR118

site_idSWS_FT_FI9
Number of Residues12
DetailsMOD_RES: N6-acetyllysine; alternate => ECO:0000250|UniProtKB:Q60930
ChainResidueDetails
CLYS120
DLYS120
ELYS120
FLYS120
GLYS120
HLYS120
ILYS120
JLYS120
KLYS120
LLYS120
MLYS120
NLYS120

site_idSWS_FT_FI10
Number of Residues12
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P21796
ChainResidueDetails
CSER251
DSER251
ESER251
FSER251
GSER251
HSER251
ISER251
JSER251
KSER251
LSER251
MSER251
NSER251

site_idSWS_FT_FI11
Number of Residues12
DetailsMOD_RES: N6-acetyllysine; alternate => ECO:0000250|UniProtKB:P21796
ChainResidueDetails
DLYS277
HLYS277
LLYS277
CLYS277
ELYS277
FLYS277
GLYS277
ILYS277
JLYS277
KLYS277
MLYS277
NLYS277

site_idSWS_FT_FI12
Number of Residues48
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000250|UniProtKB:P45880
ChainResidueDetails
HLYS120
ILYS31
ILYS120
ILYS277
JLYS31
JLYS120
JLYS277
KLYS31
KLYS120
KLYS277
LLYS31
LLYS120
LLYS277
MLYS31
MLYS120
MLYS277
NLYS31
NLYS120
NLYS277
CLYS31
CLYS120
CLYS277
DLYS31
DLYS120
DLYS277
ELYS31
ELYS120
ELYS277
FLYS31
FLYS120
FLYS277
GLYS31
GLYS120
GLYS277
HLYS31
HLYS277

site_idSWS_FT_FI13
Number of Residues24
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P45880
ChainResidueDetails
ILYS64
ILYS121
JLYS64
JLYS121
KLYS64
KLYS121
LLYS64
LLYS121
MLYS64
MLYS121
NLYS64
NLYS121
CLYS64
CLYS121
DLYS64
DLYS121
ELYS64
ELYS121
FLYS64
FLYS121
GLYS64
GLYS121
HLYS64
HLYS121

site_idSWS_FT_FI14
Number of Residues12
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P21796
ChainResidueDetails
CLYS172
DLYS172
ELYS172
FLYS172
GLYS172
HLYS172
ILYS172
JLYS172
KLYS172
LLYS172
MLYS172
NLYS172

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PDB entries from 2024-09-11

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