7NHT

Akirin2 bound human proteasome

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000502	cellular_component	proteasome complex
A	0000932	cellular_component	P-body
A	0002376	biological_process	immune system process
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005839	cellular_component	proteasome core complex
A	0006281	biological_process	DNA repair
A	0006511	biological_process	ubiquitin-dependent protein catabolic process
A	0006915	biological_process	apoptotic process
A	0006974	biological_process	DNA damage response
A	0006979	biological_process	response to oxidative stress
A	0007283	biological_process	spermatogenesis
A	0008021	cellular_component	synaptic vesicle
A	0009615	biological_process	response to virus
A	0010498	biological_process	proteasomal protein catabolic process
A	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
A	0019773	cellular_component	proteasome core complex, alpha-subunit complex
A	0030317	biological_process	flagellated sperm motility
A	0032729	biological_process	positive regulation of type II interferon production
A	0032743	biological_process	positive regulation of interleukin-2 production
A	0032760	biological_process	positive regulation of tumor necrosis factor production
A	0034341	biological_process	response to type II interferon
A	0034515	cellular_component	proteasome storage granule
A	0034774	cellular_component	secretory granule lumen
A	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
A	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
A	0045061	biological_process	thymic T cell selection
A	0045063	biological_process	T-helper 1 cell differentiation
A	0045590	biological_process	negative regulation of regulatory T cell differentiation
A	0051321	biological_process	meiotic cell cycle
A	0051603	biological_process	proteolysis involved in protein catabolic process
A	0061136	biological_process	regulation of proteasomal protein catabolic process
A	0070062	cellular_component	extracellular exosome
A	0071357	biological_process	cellular response to type I interferon
A	0072539	biological_process	T-helper 17 cell differentiation
A	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
A	1904813	cellular_component	ficolin-1-rich granule lumen
A	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
B	0000502	cellular_component	proteasome complex
B	0000932	cellular_component	P-body
B	0002376	biological_process	immune system process
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005839	cellular_component	proteasome core complex
B	0006281	biological_process	DNA repair
B	0006511	biological_process	ubiquitin-dependent protein catabolic process
B	0006915	biological_process	apoptotic process
B	0006974	biological_process	DNA damage response
B	0006979	biological_process	response to oxidative stress
B	0007283	biological_process	spermatogenesis
B	0008021	cellular_component	synaptic vesicle
B	0010498	biological_process	proteasomal protein catabolic process
B	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
B	0019773	cellular_component	proteasome core complex, alpha-subunit complex
B	0030317	biological_process	flagellated sperm motility
B	0032729	biological_process	positive regulation of type II interferon production
B	0032743	biological_process	positive regulation of interleukin-2 production
B	0032760	biological_process	positive regulation of tumor necrosis factor production
B	0034341	biological_process	response to type II interferon
B	0034515	cellular_component	proteasome storage granule
B	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
B	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
B	0045061	biological_process	thymic T cell selection
B	0045063	biological_process	T-helper 1 cell differentiation
B	0045590	biological_process	negative regulation of regulatory T cell differentiation
B	0051321	biological_process	meiotic cell cycle
B	0051603	biological_process	proteolysis involved in protein catabolic process
B	0061136	biological_process	regulation of proteasomal protein catabolic process
B	0070062	cellular_component	extracellular exosome
B	0071357	biological_process	cellular response to type I interferon
B	0072539	biological_process	T-helper 17 cell differentiation
B	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
B	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
C	0000502	cellular_component	proteasome complex
C	0002376	biological_process	immune system process
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005839	cellular_component	proteasome core complex
C	0006281	biological_process	DNA repair
C	0006511	biological_process	ubiquitin-dependent protein catabolic process
C	0006915	biological_process	apoptotic process
C	0006974	biological_process	DNA damage response
C	0006979	biological_process	response to oxidative stress
C	0008021	cellular_component	synaptic vesicle
C	0010498	biological_process	proteasomal protein catabolic process
C	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
C	0019773	cellular_component	proteasome core complex, alpha-subunit complex
C	0030317	biological_process	flagellated sperm motility
C	0032729	biological_process	positive regulation of type II interferon production
C	0032743	biological_process	positive regulation of interleukin-2 production
C	0032760	biological_process	positive regulation of tumor necrosis factor production
C	0034341	biological_process	response to type II interferon
C	0034515	cellular_component	proteasome storage granule
C	0042802	molecular_function	identical protein binding
C	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
C	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
C	0045061	biological_process	thymic T cell selection
C	0045063	biological_process	T-helper 1 cell differentiation
C	0045590	biological_process	negative regulation of regulatory T cell differentiation
C	0051603	biological_process	proteolysis involved in protein catabolic process
C	0061136	biological_process	regulation of proteasomal protein catabolic process
C	0070062	cellular_component	extracellular exosome
C	0071357	biological_process	cellular response to type I interferon
C	0072539	biological_process	T-helper 17 cell differentiation
C	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
C	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
D	0000502	cellular_component	proteasome complex
D	0002376	biological_process	immune system process
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005839	cellular_component	proteasome core complex
D	0006281	biological_process	DNA repair
D	0006511	biological_process	ubiquitin-dependent protein catabolic process
D	0006915	biological_process	apoptotic process
D	0006974	biological_process	DNA damage response
D	0006979	biological_process	response to oxidative stress
D	0007283	biological_process	spermatogenesis
D	0008021	cellular_component	synaptic vesicle
D	0010498	biological_process	proteasomal protein catabolic process
D	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
D	0019773	cellular_component	proteasome core complex, alpha-subunit complex
D	0030317	biological_process	flagellated sperm motility
D	0032729	biological_process	positive regulation of type II interferon production
D	0032743	biological_process	positive regulation of interleukin-2 production
D	0032760	biological_process	positive regulation of tumor necrosis factor production
D	0034341	biological_process	response to type II interferon
D	0034515	cellular_component	proteasome storage granule
D	0034774	cellular_component	secretory granule lumen
D	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
D	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
D	0045061	biological_process	thymic T cell selection
D	0045063	biological_process	T-helper 1 cell differentiation
D	0045590	biological_process	negative regulation of regulatory T cell differentiation
D	0051321	biological_process	meiotic cell cycle
D	0051603	biological_process	proteolysis involved in protein catabolic process
D	0061136	biological_process	regulation of proteasomal protein catabolic process
D	0070062	cellular_component	extracellular exosome
D	0071357	biological_process	cellular response to type I interferon
D	0072539	biological_process	T-helper 17 cell differentiation
D	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
D	1904813	cellular_component	ficolin-1-rich granule lumen
D	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
E	0000502	cellular_component	proteasome complex
E	0001530	molecular_function	lipopolysaccharide binding
E	0002376	biological_process	immune system process
E	0002862	biological_process	negative regulation of inflammatory response to antigenic stimulus
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005839	cellular_component	proteasome core complex
E	0006281	biological_process	DNA repair
E	0006511	biological_process	ubiquitin-dependent protein catabolic process
E	0006915	biological_process	apoptotic process
E	0006974	biological_process	DNA damage response
E	0006979	biological_process	response to oxidative stress
E	0007283	biological_process	spermatogenesis
E	0008021	cellular_component	synaptic vesicle
E	0010498	biological_process	proteasomal protein catabolic process
E	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
E	0016604	cellular_component	nuclear body
E	0019773	cellular_component	proteasome core complex, alpha-subunit complex
E	0030317	biological_process	flagellated sperm motility
E	0032729	biological_process	positive regulation of type II interferon production
E	0032743	biological_process	positive regulation of interleukin-2 production
E	0032760	biological_process	positive regulation of tumor necrosis factor production
E	0034341	biological_process	response to type II interferon
E	0034515	cellular_component	proteasome storage granule
E	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
E	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
E	0045061	biological_process	thymic T cell selection
E	0045063	biological_process	T-helper 1 cell differentiation
E	0045590	biological_process	negative regulation of regulatory T cell differentiation
E	0051321	biological_process	meiotic cell cycle
E	0051603	biological_process	proteolysis involved in protein catabolic process
E	0061136	biological_process	regulation of proteasomal protein catabolic process
E	0070062	cellular_component	extracellular exosome
E	0071357	biological_process	cellular response to type I interferon
E	0072539	biological_process	T-helper 17 cell differentiation
E	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
E	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
F	0000502	cellular_component	proteasome complex
F	0002376	biological_process	immune system process
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005839	cellular_component	proteasome core complex
F	0006281	biological_process	DNA repair
F	0006511	biological_process	ubiquitin-dependent protein catabolic process
F	0006915	biological_process	apoptotic process
F	0006974	biological_process	DNA damage response
F	0006979	biological_process	response to oxidative stress
F	0007283	biological_process	spermatogenesis
F	0008021	cellular_component	synaptic vesicle
F	0010498	biological_process	proteasomal protein catabolic process
F	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
F	0019773	cellular_component	proteasome core complex, alpha-subunit complex
F	0030317	biological_process	flagellated sperm motility
F	0031625	molecular_function	ubiquitin protein ligase binding
F	0032729	biological_process	positive regulation of type II interferon production
F	0032743	biological_process	positive regulation of interleukin-2 production
F	0032760	biological_process	positive regulation of tumor necrosis factor production
F	0034341	biological_process	response to type II interferon
F	0034515	cellular_component	proteasome storage granule
F	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
F	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
F	0045061	biological_process	thymic T cell selection
F	0045063	biological_process	T-helper 1 cell differentiation
F	0045590	biological_process	negative regulation of regulatory T cell differentiation
F	0051321	biological_process	meiotic cell cycle
F	0051603	biological_process	proteolysis involved in protein catabolic process
F	0061136	biological_process	regulation of proteasomal protein catabolic process
F	0070062	cellular_component	extracellular exosome
F	0071357	biological_process	cellular response to type I interferon
F	0072539	biological_process	T-helper 17 cell differentiation
F	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
F	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
G	0000502	cellular_component	proteasome complex
G	0000932	cellular_component	P-body
G	0002376	biological_process	immune system process
G	0003723	molecular_function	RNA binding
G	0004175	molecular_function	endopeptidase activity
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005839	cellular_component	proteasome core complex
G	0005840	cellular_component	ribosome
G	0006281	biological_process	DNA repair
G	0006511	biological_process	ubiquitin-dependent protein catabolic process
G	0006915	biological_process	apoptotic process
G	0006974	biological_process	DNA damage response
G	0006979	biological_process	response to oxidative stress
G	0007283	biological_process	spermatogenesis
G	0008021	cellular_component	synaptic vesicle
G	0010498	biological_process	proteasomal protein catabolic process
G	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
G	0016363	cellular_component	nuclear matrix
G	0019773	cellular_component	proteasome core complex, alpha-subunit complex
G	0030016	cellular_component	myofibril
G	0030017	cellular_component	sarcomere
G	0030317	biological_process	flagellated sperm motility
G	0032729	biological_process	positive regulation of type II interferon production
G	0032743	biological_process	positive regulation of interleukin-2 production
G	0032760	biological_process	positive regulation of tumor necrosis factor production
G	0034341	biological_process	response to type II interferon
G	0034515	cellular_component	proteasome storage granule
G	0035639	molecular_function	purine ribonucleoside triphosphate binding
G	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
G	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
G	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
G	0045061	biological_process	thymic T cell selection
G	0045063	biological_process	T-helper 1 cell differentiation
G	0045590	biological_process	negative regulation of regulatory T cell differentiation
G	0050727	biological_process	regulation of inflammatory response
G	0051059	molecular_function	NF-kappaB binding
G	0051321	biological_process	meiotic cell cycle
G	0051603	biological_process	proteolysis involved in protein catabolic process
G	0061136	biological_process	regulation of proteasomal protein catabolic process
G	0070062	cellular_component	extracellular exosome
G	0071357	biological_process	cellular response to type I interferon
G	0072539	biological_process	T-helper 17 cell differentiation
G	0097229	cellular_component	sperm end piece
G	0097542	cellular_component	ciliary tip
G	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
G	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
H	0000502	cellular_component	proteasome complex
H	0004175	molecular_function	endopeptidase activity
H	0004298	molecular_function	threonine-type endopeptidase activity
H	0005515	molecular_function	protein binding
H	0005576	cellular_component	extracellular region
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005839	cellular_component	proteasome core complex
H	0006281	biological_process	DNA repair
H	0006508	biological_process	proteolysis
H	0006915	biological_process	apoptotic process
H	0006974	biological_process	DNA damage response
H	0006979	biological_process	response to oxidative stress
H	0007283	biological_process	spermatogenesis
H	0008021	cellular_component	synaptic vesicle
H	0008233	molecular_function	peptidase activity
H	0010498	biological_process	proteasomal protein catabolic process
H	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
H	0016604	cellular_component	nuclear body
H	0016787	molecular_function	hydrolase activity
H	0019774	cellular_component	proteasome core complex, beta-subunit complex
H	0030317	biological_process	flagellated sperm motility
H	0034515	cellular_component	proteasome storage granule
H	0034774	cellular_component	secretory granule lumen
H	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
H	0051321	biological_process	meiotic cell cycle
H	0051603	biological_process	proteolysis involved in protein catabolic process
H	0061136	biological_process	regulation of proteasomal protein catabolic process
H	0071357	biological_process	cellular response to type I interferon
H	1904813	cellular_component	ficolin-1-rich granule lumen
H	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
I	0000502	cellular_component	proteasome complex
I	0002376	biological_process	immune system process
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005839	cellular_component	proteasome core complex
I	0006281	biological_process	DNA repair
I	0006915	biological_process	apoptotic process
I	0006974	biological_process	DNA damage response
I	0006979	biological_process	response to oxidative stress
I	0007283	biological_process	spermatogenesis
I	0008021	cellular_component	synaptic vesicle
I	0010498	biological_process	proteasomal protein catabolic process
I	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
I	0019774	cellular_component	proteasome core complex, beta-subunit complex
I	0030317	biological_process	flagellated sperm motility
I	0032729	biological_process	positive regulation of type II interferon production
I	0032743	biological_process	positive regulation of interleukin-2 production
I	0032760	biological_process	positive regulation of tumor necrosis factor production
I	0034341	biological_process	response to type II interferon
I	0034515	cellular_component	proteasome storage granule
I	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
I	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
I	0045061	biological_process	thymic T cell selection
I	0045063	biological_process	T-helper 1 cell differentiation
I	0045590	biological_process	negative regulation of regulatory T cell differentiation
I	0051321	biological_process	meiotic cell cycle
I	0051603	biological_process	proteolysis involved in protein catabolic process
I	0061136	biological_process	regulation of proteasomal protein catabolic process
I	0070062	cellular_component	extracellular exosome
I	0071357	biological_process	cellular response to type I interferon
I	0072539	biological_process	T-helper 17 cell differentiation
I	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
I	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
J	0000502	cellular_component	proteasome complex
J	0002376	biological_process	immune system process
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005839	cellular_component	proteasome core complex
J	0006281	biological_process	DNA repair
J	0006915	biological_process	apoptotic process
J	0006974	biological_process	DNA damage response
J	0006979	biological_process	response to oxidative stress
J	0007283	biological_process	spermatogenesis
J	0008021	cellular_component	synaptic vesicle
J	0010498	biological_process	proteasomal protein catabolic process
J	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
J	0016020	cellular_component	membrane
J	0019774	cellular_component	proteasome core complex, beta-subunit complex
J	0030317	biological_process	flagellated sperm motility
J	0032729	biological_process	positive regulation of type II interferon production
J	0032743	biological_process	positive regulation of interleukin-2 production
J	0032760	biological_process	positive regulation of tumor necrosis factor production
J	0034341	biological_process	response to type II interferon
J	0034515	cellular_component	proteasome storage granule
J	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
J	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
J	0045061	biological_process	thymic T cell selection
J	0045063	biological_process	T-helper 1 cell differentiation
J	0045590	biological_process	negative regulation of regulatory T cell differentiation
J	0051321	biological_process	meiotic cell cycle
J	0051603	biological_process	proteolysis involved in protein catabolic process
J	0061136	biological_process	regulation of proteasomal protein catabolic process
J	0070062	cellular_component	extracellular exosome
J	0071357	biological_process	cellular response to type I interferon
J	0072539	biological_process	T-helper 17 cell differentiation
J	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
J	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
K	0000502	cellular_component	proteasome complex
K	0004175	molecular_function	endopeptidase activity
K	0004298	molecular_function	threonine-type endopeptidase activity
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005839	cellular_component	proteasome core complex
K	0006281	biological_process	DNA repair
K	0006508	biological_process	proteolysis
K	0006915	biological_process	apoptotic process
K	0006974	biological_process	DNA damage response
K	0006979	biological_process	response to oxidative stress
K	0007283	biological_process	spermatogenesis
K	0008021	cellular_component	synaptic vesicle
K	0008233	molecular_function	peptidase activity
K	0010498	biological_process	proteasomal protein catabolic process
K	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
K	0016787	molecular_function	hydrolase activity
K	0019774	cellular_component	proteasome core complex, beta-subunit complex
K	0030317	biological_process	flagellated sperm motility
K	0034515	cellular_component	proteasome storage granule
K	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
K	0043248	biological_process	proteasome assembly
K	0051321	biological_process	meiotic cell cycle
K	0051603	biological_process	proteolysis involved in protein catabolic process
K	0061136	biological_process	regulation of proteasomal protein catabolic process
K	0070062	cellular_component	extracellular exosome
K	0071357	biological_process	cellular response to type I interferon
K	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
L	0000502	cellular_component	proteasome complex
L	0002376	biological_process	immune system process
L	0005515	molecular_function	protein binding
L	0005576	cellular_component	extracellular region
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0005839	cellular_component	proteasome core complex
L	0006281	biological_process	DNA repair
L	0006915	biological_process	apoptotic process
L	0006974	biological_process	DNA damage response
L	0006979	biological_process	response to oxidative stress
L	0007283	biological_process	spermatogenesis
L	0008021	cellular_component	synaptic vesicle
L	0010498	biological_process	proteasomal protein catabolic process
L	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
L	0019774	cellular_component	proteasome core complex, beta-subunit complex
L	0030317	biological_process	flagellated sperm motility
L	0032729	biological_process	positive regulation of type II interferon production
L	0032743	biological_process	positive regulation of interleukin-2 production
L	0032760	biological_process	positive regulation of tumor necrosis factor production
L	0034341	biological_process	response to type II interferon
L	0034515	cellular_component	proteasome storage granule
L	0034774	cellular_component	secretory granule lumen
L	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
L	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
L	0045061	biological_process	thymic T cell selection
L	0045063	biological_process	T-helper 1 cell differentiation
L	0045590	biological_process	negative regulation of regulatory T cell differentiation
L	0051321	biological_process	meiotic cell cycle
L	0051603	biological_process	proteolysis involved in protein catabolic process
L	0061136	biological_process	regulation of proteasomal protein catabolic process
L	0070062	cellular_component	extracellular exosome
L	0071357	biological_process	cellular response to type I interferon
L	0072539	biological_process	T-helper 17 cell differentiation
L	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
L	1904813	cellular_component	ficolin-1-rich granule lumen
L	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
M	0000502	cellular_component	proteasome complex
M	0001530	molecular_function	lipopolysaccharide binding
M	0002376	biological_process	immune system process
M	0002862	biological_process	negative regulation of inflammatory response to antigenic stimulus
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0005839	cellular_component	proteasome core complex
M	0006281	biological_process	DNA repair
M	0006915	biological_process	apoptotic process
M	0006974	biological_process	DNA damage response
M	0006979	biological_process	response to oxidative stress
M	0007283	biological_process	spermatogenesis
M	0008021	cellular_component	synaptic vesicle
M	0010498	biological_process	proteasomal protein catabolic process
M	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
M	0019774	cellular_component	proteasome core complex, beta-subunit complex
M	0030317	biological_process	flagellated sperm motility
M	0032729	biological_process	positive regulation of type II interferon production
M	0032743	biological_process	positive regulation of interleukin-2 production
M	0032760	biological_process	positive regulation of tumor necrosis factor production
M	0034341	biological_process	response to type II interferon
M	0034515	cellular_component	proteasome storage granule
M	0036064	cellular_component	ciliary basal body
M	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
M	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
M	0045061	biological_process	thymic T cell selection
M	0045063	biological_process	T-helper 1 cell differentiation
M	0045590	biological_process	negative regulation of regulatory T cell differentiation
M	0051321	biological_process	meiotic cell cycle
M	0051603	biological_process	proteolysis involved in protein catabolic process
M	0061136	biological_process	regulation of proteasomal protein catabolic process
M	0070062	cellular_component	extracellular exosome
M	0071357	biological_process	cellular response to type I interferon
M	0072539	biological_process	T-helper 17 cell differentiation
M	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
M	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
N	0000502	cellular_component	proteasome complex
N	0004175	molecular_function	endopeptidase activity
N	0004298	molecular_function	threonine-type endopeptidase activity
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0005839	cellular_component	proteasome core complex
N	0006281	biological_process	DNA repair
N	0006508	biological_process	proteolysis
N	0006915	biological_process	apoptotic process
N	0006974	biological_process	DNA damage response
N	0006979	biological_process	response to oxidative stress
N	0007283	biological_process	spermatogenesis
N	0008021	cellular_component	synaptic vesicle
N	0008233	molecular_function	peptidase activity
N	0010498	biological_process	proteasomal protein catabolic process
N	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
N	0016787	molecular_function	hydrolase activity
N	0019774	cellular_component	proteasome core complex, beta-subunit complex
N	0030317	biological_process	flagellated sperm motility
N	0034515	cellular_component	proteasome storage granule
N	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
N	0045296	molecular_function	cadherin binding
N	0051321	biological_process	meiotic cell cycle
N	0051603	biological_process	proteolysis involved in protein catabolic process
N	0061136	biological_process	regulation of proteasomal protein catabolic process
N	0070062	cellular_component	extracellular exosome
N	0071357	biological_process	cellular response to type I interferon
N	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
c	0000785	cellular_component	chromatin
c	0002250	biological_process	adaptive immune response
c	0002376	biological_process	immune system process
c	0002821	biological_process	positive regulation of adaptive immune response
c	0003712	molecular_function	transcription coregulator activity
c	0005515	molecular_function	protein binding
c	0005634	cellular_component	nucleus
c	0005654	cellular_component	nucleoplasm
c	0005737	cellular_component	cytoplasm
c	0006351	biological_process	DNA-templated transcription
c	0006606	biological_process	protein import into nucleus
c	0009792	biological_process	embryo development ending in birth or egg hatching
c	0015031	biological_process	protein transport
c	0016020	cellular_component	membrane
c	0017053	cellular_component	transcription repressor complex
c	0019899	molecular_function	enzyme binding
c	0021987	biological_process	cerebral cortex development
c	0030674	molecular_function	protein-macromolecule adaptor activity
c	0031144	biological_process	proteasome localization
c	0032755	biological_process	positive regulation of interleukin-6 production
c	0042742	biological_process	defense response to bacterium
c	0042802	molecular_function	identical protein binding
c	0045087	biological_process	innate immune response
c	0045089	biological_process	positive regulation of innate immune response
c	0045944	biological_process	positive regulation of transcription by RNA polymerase II
c	0050871	biological_process	positive regulation of B cell activation
c	0051147	biological_process	regulation of muscle cell differentiation
c	0071630	biological_process	nuclear protein quality control by the ubiquitin-proteasome system
d	0000785	cellular_component	chromatin
d	0002250	biological_process	adaptive immune response
d	0002376	biological_process	immune system process
d	0002821	biological_process	positive regulation of adaptive immune response
d	0003712	molecular_function	transcription coregulator activity
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0005654	cellular_component	nucleoplasm
d	0005737	cellular_component	cytoplasm
d	0006351	biological_process	DNA-templated transcription
d	0006606	biological_process	protein import into nucleus
d	0009792	biological_process	embryo development ending in birth or egg hatching
d	0015031	biological_process	protein transport
d	0016020	cellular_component	membrane
d	0017053	cellular_component	transcription repressor complex
d	0019899	molecular_function	enzyme binding
d	0021987	biological_process	cerebral cortex development
d	0030674	molecular_function	protein-macromolecule adaptor activity
d	0031144	biological_process	proteasome localization
d	0032755	biological_process	positive regulation of interleukin-6 production
d	0042742	biological_process	defense response to bacterium
d	0042802	molecular_function	identical protein binding
d	0045087	biological_process	innate immune response
d	0045089	biological_process	positive regulation of innate immune response
d	0045944	biological_process	positive regulation of transcription by RNA polymerase II
d	0050871	biological_process	positive regulation of B cell activation
d	0051147	biological_process	regulation of muscle cell differentiation
d	0071630	biological_process	nuclear protein quality control by the ubiquitin-proteasome system

Functional Information from PROSITE/UniProt

site_id	PS00388
Number of Residues	23
Details	PROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. YdlsaStFSPdGRvfQVEYAmkA

Chain	Residue	Details
F	TYR7-ALA29
D	TYR8-ALA30
B	TYR5-ALA27
C	TYR3-ALA25
A	TYR5-ALA27
G	PHE9-ALA31
E	TYR6-ALA28

---

site_id	PS00854
Number of Residues	48
Details	PROTEASOME_BETA_1 Proteasome beta-type subunits signature. AGVvYkdGIVLGADtrategmvvadkncs.KihfispniyccgaGtaAD

Chain	Residue	Details
H	ALA4-ASP51
B	LEU35-ASP82
M	LEU12-ASP59
N	MET4-ASP51
K	LEU4-ASP51
L	LEU13-ASP60
J	ILE5-ASP52
I	MET11-ASP58

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P49722","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	11
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	12
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P17220","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17323924","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine; by ABL1 and ABL2","evidences":[{"source":"PubMed","id":"16678104","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	5
Details	Glycosylation: {"description":"O-linked (GlcNAc) serine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"UniProtKB","id":"Q9Z2U1","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"16964243","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; alternate","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	1
Details	Glycosylation: {"description":"O-linked (GlcNAc) serine; alternate","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	3
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)"}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17323924","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q9QUM9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	3
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"25599644","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27493187","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUL-2008","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","von Kriegsheim A.F.","Kolch W."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18502982","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18565852","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19426847","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"O09061","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	6
Details	Motif: {"description":"SYVS motif","evidences":[{"source":"PubMed","id":"34711951","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---