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7NGK

Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound

Functional Information from GO Data
ChainGOidnamespacecontents
A0000976molecular_functiontranscription cis-regulatory region binding
A0003677molecular_functionDNA binding
A0003700molecular_functionDNA-binding transcription factor activity
A0005515molecular_functionprotein binding
A0005829cellular_componentcytosol
A0006355biological_processregulation of DNA-templated transcription
A0045892biological_processnegative regulation of DNA-templated transcription
A0046677biological_processresponse to antibiotic
Functional Information from PDB Data
site_idAC1
Number of Residues9
Detailsbinding site for residue UAE A 302
ChainResidue
AGLY106
AILE107
APHE110
AMET142
ATRP145
ATHR149
AASN176
AASN179
ATRP207

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues19
DetailsDNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00335
ChainResidueDetails
ASER46-PHE65

site_idSWS_FT_FI2
Number of Residues2
DetailsSITE: Inhibitor-binding
ChainResidueDetails
AASN176
AASN179

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PDB entries from 2024-11-06

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