7NFY

P1a-state of wild type human mitochondrial LONP1 protease with bound substrate protein and ATPgS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004176	molecular_function	ATP-dependent peptidase activity
A	0004252	molecular_function	serine-type endopeptidase activity
A	0005524	molecular_function	ATP binding
A	0006508	biological_process	proteolysis
A	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
A	0016887	molecular_function	ATP hydrolysis activity
A	0030163	biological_process	protein catabolic process
B	0004176	molecular_function	ATP-dependent peptidase activity
B	0004252	molecular_function	serine-type endopeptidase activity
B	0005524	molecular_function	ATP binding
B	0006508	biological_process	proteolysis
B	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
B	0016887	molecular_function	ATP hydrolysis activity
B	0030163	biological_process	protein catabolic process
C	0004176	molecular_function	ATP-dependent peptidase activity
C	0004252	molecular_function	serine-type endopeptidase activity
C	0005524	molecular_function	ATP binding
C	0006508	biological_process	proteolysis
C	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
C	0016887	molecular_function	ATP hydrolysis activity
C	0030163	biological_process	protein catabolic process
D	0004176	molecular_function	ATP-dependent peptidase activity
D	0004252	molecular_function	serine-type endopeptidase activity
D	0005524	molecular_function	ATP binding
D	0006508	biological_process	proteolysis
D	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
D	0016887	molecular_function	ATP hydrolysis activity
D	0030163	biological_process	protein catabolic process
E	0004176	molecular_function	ATP-dependent peptidase activity
E	0004252	molecular_function	serine-type endopeptidase activity
E	0005524	molecular_function	ATP binding
E	0006508	biological_process	proteolysis
E	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
E	0016887	molecular_function	ATP hydrolysis activity
E	0030163	biological_process	protein catabolic process
F	0004176	molecular_function	ATP-dependent peptidase activity
F	0004252	molecular_function	serine-type endopeptidase activity
F	0005524	molecular_function	ATP binding
F	0006508	biological_process	proteolysis
F	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
F	0016887	molecular_function	ATP hydrolysis activity
F	0030163	biological_process	protein catabolic process

Functional Information from PROSITE/UniProt

site_id	PS01046
Number of Residues	9
Details	LON_SER ATP-dependent serine proteases, lon family, serine active site. DGPSAGCTI

Chain	Residue	Details
A	ASP852-ILE860

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_03120

Chain	Residue	Details
A	SER855
E	LYS898
F	SER855
F	LYS898
A	LYS898
B	SER855
B	LYS898
C	SER855
C	LYS898
D	SER855
D	LYS898
E	SER855

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site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03120

Chain	Residue	Details
A	GLY523
B	GLY523
C	GLY523
D	GLY523
E	GLY523
F	GLY523

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