7NED
Thiourocanate hydratase from Paenibacillus sp. Soil724D2 in complex with cofactor NAD+ and urocanate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006547 | biological_process | histidine metabolic process |
| A | 0006548 | biological_process | histidine catabolic process |
| A | 0016153 | molecular_function | urocanate hydratase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019556 | biological_process | histidine catabolic process to glutamate and formamide |
| A | 0019557 | biological_process | histidine catabolic process to glutamate and formate |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue URO A 701 |
| Chain | Residue |
| A | TYR42 |
| A | HOH931 |
| A | LEU122 |
| A | THR123 |
| A | TYR129 |
| A | MET168 |
| A | ARG352 |
| A | ASP433 |
| A | NAD702 |
| A | HOH822 |
| site_id | AC2 |
| Number of Residues | 28 |
| Details | binding site for residue NAD A 702 |
| Chain | Residue |
| A | TYR42 |
| A | ALA43 |
| A | ALA44 |
| A | GLY166 |
| A | GLY167 |
| A | MET168 |
| A | GLY169 |
| A | GLU187 |
| A | VAL188 |
| A | ARG192 |
| A | GLY232 |
| A | ASN233 |
| A | ALA234 |
| A | GLN254 |
| A | THR255 |
| A | SER256 |
| A | HIS258 |
| A | TYR264 |
| A | VAL265 |
| A | GLY314 |
| A | ASN315 |
| A | ILE445 |
| A | TYR485 |
| A | URO701 |
| A | HOH807 |
| A | HOH822 |
| A | HOH829 |
| A | HOH1013 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 703 |
| Chain | Residue |
| A | ARG3 |
| A | GLY33 |
| A | GLU34 |
| A | ASN35 |
| A | GLN36 |
| A | LYS37 |
