Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0042981 | biological_process | regulation of apoptotic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0042981 | biological_process | regulation of apoptotic process |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0042981 | biological_process | regulation of apoptotic process |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0042981 | biological_process | regulation of apoptotic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue U6N A 401 |
| Chain | Residue |
| A | HIS224 |
| A | GLY271 |
| D | HIS224 |
| D | ALA227 |
| D | U6N401 |
| A | ALA227 |
| A | PHE228 |
| A | MET231 |
| A | MET250 |
| A | ARG263 |
| A | THR266 |
| A | LEU267 |
| A | PHE270 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue U6N B 401 |
| Chain | Residue |
| B | ALA227 |
| B | PHE228 |
| B | MET231 |
| B | ARG263 |
| B | THR266 |
| B | LEU267 |
| B | PHE270 |
| B | GLY271 |
| B | HOH501 |
| C | HIS224 |
| C | ALA227 |
| C | U6N401 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue U6N C 401 |
| Chain | Residue |
| B | HIS224 |
| B | ALA227 |
| B | U6N401 |
| C | HIS224 |
| C | ALA227 |
| C | PHE228 |
| C | VAL253 |
| C | ARG263 |
| C | THR266 |
| C | LEU267 |
| C | PHE270 |
| C | GLY271 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for residue U6N D 401 |
| Chain | Residue |
| A | HIS224 |
| A | U6N401 |
| D | ALA227 |
| D | PHE228 |
| D | MET231 |
| D | VAL249 |
| D | ARG263 |
| D | THR266 |
| D | LEU267 |
| D | PHE270 |
| D | GLY271 |
Functional Information from PROSITE/UniProt
| site_id | PS01080 |
| Number of Residues | 20 |
| Details | BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. VFsDGvtNWGRIVTLIsFGA |
| Chain | Residue | Details |
| A | VAL253-ALA272 | |
| site_id | PS01258 |
| Number of Residues | 12 |
| Details | BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WLvkqRGWDgFV |
| Chain | Residue | Details |
| A | TRP305-VAL316 | |
| site_id | PS01259 |
| Number of Residues | 15 |
| Details | BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. AletLRrVGDGVQRN |
| Chain | Residue | Details |
| A | ALA209-ASN223 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 56 |
| Details | Motif: {"description":"BH3"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 80 |
| Details | Motif: {"description":"BH1"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 60 |
| Details | Motif: {"description":"BH2"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)"} |
