7NB6
Structure of the autoinducer-2 exporter TqsA from E. coli
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0009372 | biological_process | quorum sensing |
| A | 0015562 | molecular_function | efflux transmembrane transporter activity |
| A | 0016020 | cellular_component | membrane |
| A | 0055085 | biological_process | transmembrane transport |
| A | 1905887 | biological_process | autoinducer AI-2 transmembrane transport |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0009372 | biological_process | quorum sensing |
| B | 0015562 | molecular_function | efflux transmembrane transporter activity |
| B | 0016020 | cellular_component | membrane |
| B | 0055085 | biological_process | transmembrane transport |
| B | 1905887 | biological_process | autoinducer AI-2 transmembrane transport |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0009372 | biological_process | quorum sensing |
| C | 0015562 | molecular_function | efflux transmembrane transporter activity |
| C | 0016020 | cellular_component | membrane |
| C | 0055085 | biological_process | transmembrane transport |
| C | 1905887 | biological_process | autoinducer AI-2 transmembrane transport |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0009372 | biological_process | quorum sensing |
| D | 0015562 | molecular_function | efflux transmembrane transporter activity |
| D | 0016020 | cellular_component | membrane |
| D | 0055085 | biological_process | transmembrane transport |
| D | 1905887 | biological_process | autoinducer AI-2 transmembrane transport |
| E | 0005886 | cellular_component | plasma membrane |
| E | 0009372 | biological_process | quorum sensing |
| E | 0015562 | molecular_function | efflux transmembrane transporter activity |
| E | 0016020 | cellular_component | membrane |
| E | 0055085 | biological_process | transmembrane transport |
| E | 1905887 | biological_process | autoinducer AI-2 transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 255 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305 |
| Chain | Residue | Details |
| A | MET1-PRO4 | |
| C | GLN52-ARG61 | |
| C | LYS171-TYR196 | |
| C | LEU243-GLY257 | |
| D | MET1-PRO4 | |
| D | GLN52-ARG61 | |
| D | LYS171-TYR196 | |
| D | LEU243-GLY257 | |
| E | MET1-PRO4 | |
| E | GLN52-ARG61 | |
| E | LYS171-TYR196 | |
| A | GLN52-ARG61 | |
| E | LEU243-GLY257 | |
| A | LYS171-TYR196 | |
| A | LEU243-GLY257 | |
| B | MET1-PRO4 | |
| B | GLN52-ARG61 | |
| B | LYS171-TYR196 | |
| B | LEU243-GLY257 | |
| C | MET1-PRO4 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 800 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE5-CYS25 | |
| B | ALA31-VAL51 | |
| B | VAL62-TYR82 | |
| B | SER150-GLY170 | |
| B | LEU197-ALA217 | |
| B | PHE222-VAL242 | |
| B | PHE258-ILE278 | |
| B | LEU293-LEU313 | |
| C | ILE5-CYS25 | |
| C | ALA31-VAL51 | |
| C | VAL62-TYR82 | |
| A | ALA31-VAL51 | |
| C | SER150-GLY170 | |
| C | LEU197-ALA217 | |
| C | PHE222-VAL242 | |
| C | PHE258-ILE278 | |
| C | LEU293-LEU313 | |
| D | ILE5-CYS25 | |
| D | ALA31-VAL51 | |
| D | VAL62-TYR82 | |
| D | SER150-GLY170 | |
| D | LEU197-ALA217 | |
| A | VAL62-TYR82 | |
| D | PHE222-VAL242 | |
| D | PHE258-ILE278 | |
| D | LEU293-LEU313 | |
| E | ILE5-CYS25 | |
| E | ALA31-VAL51 | |
| E | VAL62-TYR82 | |
| E | SER150-GLY170 | |
| E | LEU197-ALA217 | |
| E | PHE222-VAL242 | |
| E | PHE258-ILE278 | |
| A | SER150-GLY170 | |
| E | LEU293-LEU313 | |
| A | LEU197-ALA217 | |
| A | PHE222-VAL242 | |
| A | PHE258-ILE278 | |
| A | LEU293-LEU313 | |
| B | ILE5-CYS25 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 430 |
| Details | TOPO_DOM: Periplasmic => ECO:0000305 |
| Chain | Residue | Details |
| A | GLY26-ALA30 | |
| C | LEU83-SER149 | |
| C | LEU218-ARG221 | |
| C | LEU279-THR292 | |
| D | GLY26-ALA30 | |
| D | LEU83-SER149 | |
| D | LEU218-ARG221 | |
| D | LEU279-THR292 | |
| E | GLY26-ALA30 | |
| E | LEU83-SER149 | |
| E | LEU218-ARG221 | |
| A | LEU83-SER149 | |
| E | LEU279-THR292 | |
| A | LEU218-ARG221 | |
| A | LEU279-THR292 | |
| B | GLY26-ALA30 | |
| B | LEU83-SER149 | |
| B | LEU218-ARG221 | |
| B | LEU279-THR292 | |
| C | GLY26-ALA30 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 150 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:15919996 |
| Chain | Residue | Details |
| A | SER314-GLU344 | |
| B | SER314-GLU344 | |
| C | SER314-GLU344 | |
| D | SER314-GLU344 | |
| E | SER314-GLU344 |
